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TheLiverDoc Profile picture
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13 May, 7 tweets, 4 min read
This is irresponsible.

More so, this is a sales advertisement that claims health benefits, but has very little scientific evidence to recommend

This is a business tweet

Benefits of eucalyptus oil in humans 4 inhalational purpose is not scientifically proven

Let us discuss

1/
Eucalyptus oil is an essential oil.
Why is it called essential?
It is just falsely named so, to impress on the user.
They are absolutely not essential


2/
There are no humans studies done on eucalyptus oils - as inhalational agents or in other forms to showcase its health benefits.

Very low quality cell, tissue, human data as antibacterial and opiniated reviews on eucalyptus oils exist in literature

ncbi.nlm.nih.gov/pmc/articles/P…

3/
But beware, eucalyptus oil is one of the most toxic substances known to man.

The only use is to spread some nice smell in the room. Do not use it for medicinal purposes especially in children

Because...



4/
...there have been reports of seizures associated with inhaling eucalyptus oil steaming

And one must be careful about this during #COVIDEmergency as it does nothing for lung health

5/
pubmed.ncbi.nlm.nih.gov/29588965/
For an excellent read on essential oils, please see this thread by @jtrebach

Where he mentions that eucalyptus oil use is associated with life threatening events

6/
Ideally the original tweeter should have mentioned:

"Eucalyptus oil for sale, for purpose of fragrance in your homes. Do not use it for medicinal purposes as there is no evidence that it improves lung health."

This would have been a more ethical and moral sales pitch.

7/7
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More from @drabbyphilips

TheLiverDoc Profile picture
13 May
India's terrible and nonsense craze about health benefits of cow urine

What are claims?
Kills germs
Protects heart and brain
Protects organs in general
Detoxifies body
Using in eye will improve eye sight
Older the urine, better benefits (?like honey)
Avoid plastic container

1/
Is cow urine good antibiotic, antifungal or antiviral?
This review on antimicrobial function of cow urine is rich in studies conducted on cells and tissue cultures.
ncbi.nlm.nih.gov/pmc/articles/P…
They have reviewed extensively on in-vitro studies between diff types of cow breeds...

2/
...when urine from every cow is same.

Gujarati Geer cow doesnt produce urine quality different from Karnataka Amrit Mahal cow

But yes, there were studies comparing different breeds as per review which is inherently foolishness

Antimicrobial discovery follows a method...

3/
Read 12 tweets
TheLiverDoc Profile picture
13 May
Great session moderated by @chiragbarjatyaa on whey protein supplementations.

To add on to this, there is definitely a lot of confusion regarding adverse effects of whey protein in general and patient population

Here is one such paper cdnsciencepub.com/doi/abs/10.113… in which...

1/
...authors mention that (abusive) use of whey (abusive - not defined) was associated with liver and kidney injury

They also mention - chronic use (not defined) and without professional guidance use of whey was associated with (some) liver and kidney side effects

Upfront...

2/
...this systematic review is scary.

It will confuse the reader and deter those who wish to use whey supplements

But, see this letter to the editor by another group of authors criticizing the original paper cdnsciencepub.com/doi/10.1139/ap…

One can notice that the paper was...

3/
Read 14 tweets
TheLiverDoc Profile picture
12 May
//When I had Covid, I used Siddha medicine and it worked//
Let us discuss

This is Placebo effect, a type of cognitive bias

"If we believe a treatment will work, it often will have a small physiological effect"

Even if treatment were absent, outcome would have been same
1/
Why did you have Placebo effect?
Becoz of another cognitive bias

Survivorship bias
"We tend to focus on thos things that survived a process and overlook ones that failed"

This happens when you see/read many testimonials on Siddha working in others who also suffer from biases
2/
These two biases create another bias.
Blind Spot bias

We dont think we have bias, but see it in others more than ourselves

So when science tells you that there is no evidence to demonstrate any benefit of Siddha in treatment of Covid, you consider scientists as biased
3/
Read 7 tweets
TheLiverDoc Profile picture
12 May
1
Im quoted in report on #2DG, drug by #DRDO, marketd by #DRreddys 4 #CovidIndia. Issues R well highlightd by @neutranino in @the_hindu 'Repurposed' use is questionable
This 'approval' doesnt bring ray of hope, but doubts on drug regulation in #india
A🧵
thehindu.com/news/national/…
2
#2deoxy2glucose is basically glucose molecule in wich 2-hydroxyl group replaced by hydrogen, so that it cannot undergo further glycolysis (which is the metabolic pathway that converts glucose to pyruvate and a hydrogen ion, during which, the free energy released in process...
3...is used to form high-energy molecules such as ATP or NADH that helps in various cell functions). So basically, by using 2DG, the normal glycolysis doesnt happen and cell functions get blocked. This is the reason it is used for cancers
Cancer cells depend heavily on glucose...
Read 11 tweets
TheLiverDoc Profile picture
11 May
Y #Ivermectin doesn't work
1 #ivermectin craze 4 #COVID19India started in South-America, spread like wildfire to USA/Europe. Heavily criticized in countries upholding #science, didnt find place in guidelines. BUT, nw it reached #India, into minds/hearts of doctors not due to...
2...the #science, but bcoz National institutions such as @aiims_newdelhi/ certain govts @goacm endorse it - without getting into the science of it. Nw, #ivermectin is slowly bcoming nationalist boy scout of #medicine in #India, wrngly endorsed by naïve students/senior professors.
3 Ivermectin is broad-spectrum antiparasitic approved by @US_FDA, proved to be safe at dose of ≤200 µg/kg. In a 60 kg man, the max conventional dose in 12 mg.
Caly et al (not Baba Ramdev) bit.ly/3vO9cuK identified in-vitro (cell study) anti-#SARSCoV2 ivermectin activity
Read 20 tweets
TheLiverDoc Profile picture
9 May
1
I challenge ur narrative tat alternative medicine works
It doesnt/#neem studies tat u keep quoting, are NOT peer-reviewed, NOT published/has been collecting dust in preprint server since Apr 2020
Tis makes ur argument invalid
But #science is kind, so lets discus
#MedTwitter
2
indiarxiv.org/pyqx4/ This is UR molecular docking study u uploaded to preprint. Y was this never published? Bcoz this is highly flawed from methods to results to conclusions. Molecular docking was blind - hence ligand optimization is not accurate...
#ayush
3
...and grid coordinates wer computer generated. Hw did u correct for tis? U cud hav used predicted binding sites 2 improve accuracy/efficiency
ncbi.nlm.nih.gov/pmc/articles/P…
Predicted binding sites 4 #SARSCoV2 is widely published/ use of grid-based docking wud be better...
Read 14 tweets

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