1/n This thread is not about Medicine, Science or Lung Disease. It’s about what you should ask when when you hear about another cycle of violence in #IsraelPalestine. Written in #Solidarity with the Jews & Arabs who today stand together against racism & hate #TrueHeroes
2/n When people speak about “country x’s right to defend itself” - what you should ask, does the leadership of country x have the right to provoke violence? and do the actions taken really constitute defense or serve another agenda? #KnowWhatToAsk#IsraelPalestine
3/n When they say but “look at the violence in the streets by the minority ” - what you should ask, is what has been done to the minority , how many have been dispossessed, killed without recourse, disenfranchised and for how long? #IsraelPalestine#EndTheOppression
4/n And when violence is periodic, ask what is the trigger, the provocation. And when they say “we have to oppress the other for our safety” you just ask - you have now oppressed them for seventy four years - are you really safer? #IsraelPalestine
5/n As you gather your thoughts, I suggest you ask yourself, who benefits from this continued, senseless, cruel situation? #IsraelPalestine#WhoBenefits
6/n Because in Israel/Palestine the answer who does not benefit is clear. The dead, the wounded, the injured, obviously do not benefit, nor do their families, friends, communities #IsraelPalestine#WhoBenefits
7/n If you think about this, even those incited, those who carry out the acts of hate, even the killings do not benefit. Think about it. Think about it again - they don’t benefit #IsraelPalestine
8/n For me this is personal. my parents were refugees. They lost their families & communities to genocide driven by racism, facilitated by indifference. They never expected hate & repression to be promoted in their name, by their people #NotInMyName#IsraelPalestine#NeverAgain
10/n Hearing the #StandWithIsreal misinformation, as a Jewish Israeli descendant to refugees & survivors I feel I have to take a public stand - criticizing the current Israeli regimes actions against Palestinian Arabs is #Not#Antisemitism - it is the #RightThingToDo
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1/n Usually we invite friends/colleagues to our SEDER, but no guests last & this year. Inspired by FB comment by @gregggonsalves I thought it’d be fun to share our dishes with #MedTwitter friends as if we’re together - see following thread #PCCMEats#HappyPassover2021
2/n Every item on the Seder Plate has a symbolic meaning in the ceremonial retelling of the Exodus story - except the Orange, a recent addition dedicated to #inclusion of those marginalized in traditional religions (women, LGBTQ) #NKsSederTweetorial#PCCMEats#HappyPassover2021
3/n The bitter & spicy taste of horseradish, fresh taste of greens & Sweet & earthy look of Harosset all symbolize aspects of the story - but biggest mystery is how well they fit together in a Matzah sandwich - or is it not? #NKsSederTweetorial#PCCMEats#HappyPassover2021
2/n As expected, type-1 IFN signature dominates all cell types (with a uniquely IFN-activated CD8 T cell cluster). The signature correlates strongly with initial viral load and in repeated samples with time #COVID19#Covid19CellAtlasmedrxiv.org/content/10.110…
3/n A skewed immunopralysis like anti-inflammatory signature is found in monocytes of #COVID19 progressive patients, connectome analysis suggested disrupted connectivity between LAG3 and MHC signalling medrxiv.org/content/10.110…
2/n Among epithelial cells, we identified cells DISTINCT from ANY epithelial cells previously described in human lungs. These aberrant basaloid cells are at the edge of myofibroblast foci & express fibrotic molecules & regulators #IPFCellAtlas#CureIPFadvances.sciencemag.org/content/6/28/e…
3/n Among enodthelial cells we discovered a previously undescribed population of COL15A1+ CD31+ cells. They are usually restricted to the airway but in IPF are found in the lung parenchyma - what are they doing there? #IPFCellAtlas#scRNAseq#CureIPFadvances.sciencemag.org/content/6/28/e…
1/n Dr. Mark Siegel is a superb critical care physician, ethicist & legendary Internal Medicine Residency Program Director whose weekly notes I read eagerly. This week’s note is titled “what I’d say to new interns” #MarksWisdom#TipsForNewDocs#MedEd facebook.com/1444114056/pos…
2/n Siegel starts saying #COVID19 took away joys of orientation: pizza, hot dogs, cold beer, gelato, unscripted conversations & new friendships. But don’t worry, show up, work hard, don't worry, you'll do great & then follows with 14 SPECIFIC TIPS: #MarksWisdom#TipsForNewDocs
3/n Tip #1: Take your own histories. Charts are rife with inaccurate, missing information. Key exposures, mounting symptoms, details patients held back- until you asked. To paraphrase Osler, patients will tell you the diagnosis, if you listen. #MarksWisdom#TipsForNewDocs#MedEd
1/n This is a thread about microRNA therapeutics in pulmonary fibrosis summarizing the MiRagen call today - we've been collaborating for >6 years now through an NIH-NHLBI funded CADET II grant to develop mir-29 as a therapy - the progress is amazing! #CureIPF#Mir29
3/n Rusty Montgomery @rmontonio of MiRagen: The Mir-29 mimic Remlarsen has hit fibrosis targets in a phase 1 trial of Keloid formation - a phase II trial is happening #AntiKeloid#CureScarring
Reopening thread to our patients 1/8 (relevant also friends, neighbors, family, peers, all) - many years ago, a veteran of many wars told me that the days of ceasefire were very dangerous. This was because precautions were lifted but risk was still there (see next) #COVID19
Reopening thread to our patients 2/8 - During ceasefires soldiers & civilians are often injured because they let down their guards, while local commanders are not aware of ceasefire or simply disregard it. Do not let your guards down - #COVID19 is not gone yet #KeepSafe
Reopening thread to our patients 3/8 - The decision to open up now is operational and involves risk. There is nothing magical about June 1 - #COVID19 does not read the calendar & is not involved in local politics. The Pandemic is not over yet. Maintain your precautions