Thread by @KrutikaKuppalli

Here is a link to the @MMWR with the data from the #Provincetown outbreak which led @CDCgov to change their recommendation on #Masks due to the #DeltaVariant

Here is a🧵highlighting the important points
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cdc.gov/mmwr/volumes/7…

-There were 469 cases of #COVID19 in Barnstable, MA in July 2021
- 346 (74%) cases in fully #vaccinated
- #Sequencing in 119/133 (89%) specimens confirmed #DeltaVariant
-274 (79%) with breakthrough infection were symptomatic
-4/5 hospitalized were fully #vaccinated

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-Ct value similar in fully vax'd (127) vs. those not (84) (22.7 vs 21.5)
-Most cases in males (85%); median age 40
-Time from vax completion -> infection 86 d (6-178 d)
- Vax as cause for breakthrough
#PfizerBiontech (159,46%)
#Moderna (131,38%)
#Janssen (56,16%)

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274 (79%) w/ breakthrough infection had si/sx
- Cough
- Headache
- Sore throat
- Muscle aches
- Fever

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What does this mean?
- Confirms the #DeltaVariant is bad
- People who have non-specific symptoms even if #vaccinated should be concerned about #COVID19
- Delta causes similar viral load in those vax'd vs those who are not

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Questions from these data
- Why was there such a propensity for men (85%) to have breakthrough
- Was severity of disease different the further out from #vaccine individuals were
- What were Ab titers in those with breakthrough
- Does being vax'd protect against #LongCovid

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