I see people are still debating what is the level of protection from 2-dose vaccine against symptomatic #covid19.Enough studies now show at ~6 months post vaccination it is <50% efficacy and frequently close 0%,meaning without masks rate of infection is the same for vax/unvax 1/
https://twitter.com/Mike_aka_Logiqx/status/1436982536039772161
but protection against severe/death is still good at 6 months (~70% efficacy).
But due to the uncertain nature of the level of Ab titers and its waning speed, immune priming or failing, and underlying conditions, is it better to wear the masks pretty much constantly outside 2/
But due to the uncertain nature of the level of Ab titers and its waning speed, immune priming or failing, and underlying conditions, is it better to wear the masks pretty much constantly outside 2/
some may ask how long should we wear the mask or social distance?
with first-generation #COVID19 vaccines, based on their efficacy, how they work, how long, it will be unrealistic to expect we could go back to pre-2020 behavior, even with 100% vaccination rates.
3/
with first-generation #COVID19 vaccines, based on their efficacy, how they work, how long, it will be unrealistic to expect we could go back to pre-2020 behavior, even with 100% vaccination rates.
3/
if 3rd dose will be effective against symptomatic #COVID19 after 1 year, then there is a possibility to break the chain of viral transmission. However, as long as vaccination doesn't prevent forward transmission after infection, a chain of transmission cannot be stopped
4/
4/
chain of transmission by itself would not be a problem for the "healthy" vaccinated population except when it finds vulnerable people. vulnerable people, this category is very broad. they will be defenseless even with vaccination. the only defense is to stop viral circulation
5/
5/
and to stop viral circulation we need a vaccine that stops viral transmission. right now, first-generation vaccines cannot do that. so, going back to pre-2020 behavior is unrealistic. It will be madness b/c no country, even now, experienced a full blow of the #SARSCoV2
6/
6/
as no country, even now, ever went back fully to pre-2020 behavior for any significant amount of time without incurring the unbearable cost to their population. 7/
when vaccines work, they work but we don't know why they work, because when they work gov/science interest in studying it evaporates as it solves their problem. so they move on. when they don't work, then there is more interest to study it. we are in a limbo right now
8/
8/
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