Here, co-ingestion of cluster dextrin with meat protein hydrolysate did not augment postprandial amino acid availability or myofibrillar FSR as compared to co-ingestion of glucose during recovery from a whole-body resistance exercise despite increased intramuscular signaling.
- Cluster dextrin is a branched carbohydrate produced from waxy maize starch by the cyclization of a branching enzyme.
It has been shown to increase the rate of gastric emptying compared to glucose and standard dextrin due to a lower osmotic pressure.
Thus, the rapid gastric emptying of cluster dextrin might alleviate the lower amino acid availability when co-ingested with protein as compared to glucose.
- Meat protein hydrolysate (0.6 g protein/FFM) mixed with either 75 g of glucose or cluster dextrin in 350 mL of cold tap water.
- Co-ingestion of cluster dextrin with meat protein hydrolysate did not enhance the total availability of protein-derived amino acids in the circulation compared with glucose.
- Interestingly, the activation of mTORC1 signaling was higher in cluster dextrin than glucose following whole-body resistance exercise.
- However, this enhanced activation of mTORC1 signaling did not increase postprandial myofibrillar protein fractional synthetic rate in cluster dextrin as compared to glucose.
Co-ingestion of cluster dextrin carbohydrate does not increase exogenous protein-derived amino acid release or myofibrillar protein synthesis following a whole-body resistance exercise in moderately trained younger males: a double-blinded randomized controlled crossover trial

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Feb 22
This systematic review and meta-analysis of RCTs comes to the conclusion that ~700 METs-min/week is the minimal dose to elicit clinically important changes in cognition in older adults.
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- 724 METs-min per week is slightly above the lower bound of WHO recommended level of physical activity (i.e. 600 METs-min per week, equivalent to 150 min/week of moderate intensity or 75 min/week of vigorous activity).
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Feb 22
This one suggests that conventional daily caffeine intake does not provide sufficient time for the elimination of caffeine and paraxanthine. Image
- Worse still, even though the salivary caffeine nearly reaches a clear state, the caffeine-associated brain responses seem to require a longer time to be fully restored.
"The concurrence of a reduced hippocampal GM intensity and an incomplete caffeine elimination, together with a GM recovery after being deprived of caffeine, underscore the importance of a sufficient cessation period...
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Feb 22
This Mendelian randomization analysis suggests that VAT mass is associated with a wide range of CVD outcomes including coronary heart disease, cardiac arrhythmia, vascular diseases, and stroke, with some circulating proteins being potential mediators of this association. Image
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Feb 22
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Feb 22
This study explored the effect of three different modes of resistance training on appetite hormones, cardiometabolic and anthropometric measures in males with obesity.
- 44 males with obesity were randomized to traditional resistance training (TRT, n = 11), circuit resistance training (CRT, n = 11), interval resistance training (IRT, n = 11) or control (C, n = 11) groups.
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This one suggests that individuals with high serum microRNA-122 levels may be less responsive during diet/physical activity-induced weight loss, as far as hepatic fat content loss is concerned.
- In the current study of participants with abdominal obesity or dyslipidemia from an 18-month randomized, controlled diet and physical activity intervention trial, it was observed that serum miR-122 levels were positively associated with hepatic fat percentage at baseline.
- A greater elevation in miR-122 from baseline to 18 months was associated with a smaller reduction in hepatic fat content during the 18-month intervention process.
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