Thread by @vipintukur

#Covid becomes much more dreaded disease in company with other respiratory viruses!!

Clinical outcomes of co-infection with influenza viruses, respiratory syncytial virus, or adenoviruses in 212 466 adults with #SARS2 infection. 1/

Viral co-infection was detected in 583 (8·4%) patients: 227 patients had influenza viruses, 220 patients had RSV, and 136 patients had adenoviruses. 2/

Co-infection with influenaza viruses was associated with increased odds of receiving invasive mechanical ventilation compared with SARS2 monoinfection
SARS2 co-infections with influenza viruses & adenoviruses were each significantly associated with increased odds of death. 3/

Influenza virus co-infection significantly increased the odds of receiving invasive mechanical ventilation & the odds of in-hospital mortality.

-4x greater odds of needing a ventilator

-2x greater odds of dying. 4/

thelancet.com/journals/lance…