Monkeypox virus clearly is endemic in #Nigeria.
Cases occur sporadically throughout the year and across the country except to the far northeast.

#Monkeypox cases continue to occur in Nigeria this year (2022): 110 suspected and 31 confirmed cases
1/
👇
ncdc.gov.ng/diseases/sitre…
The above report does not indicate which of the 2 clades of #MonkeypoxVirus are responsible for the cases.

The reported case fatality rate of 3.6% is higher than the usual 1% for the West African clade but lower than the up to 10% for the Central African clade.
2/

#Nigeria
The report does not indicate if the reported cases are due to person-to-person transmission or to contact with infected wild mammals.

#monkeys are not the reservoirs of the virus, despite the name that the virus has received.
3/
The main reservoirs of #MonkeypoxVirus are suspected to be rodents, including rope squirrels (Funisciurus spp, an arboreal rodent) and terrestrial rodents in the genera Cricetomys and Graphiurus.

4/
Halting the bushmeat trade and consumption of wild animals to halt #MonkeypoxVirus exposure will be culturally & economically difficult.

Monkeypox virus virus has been shown to be transmitted between people in #Africa, but not readily.
5/

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More from @guerreroespejo

Jun 12
Unprecedented case series advances promise of #phage therapy
👇
Phage Therapy of #Mycobacterium Infections: Compassionate-use of Phages in 20 Patients with Drug-Resistant Mycobacterial Disease
1/
academic.oup.com/cid/advance-ar…
@MariadelMarTom
Treatment of Non-tuberculous Mycobacterium could be challenging due to intrinsic antibiotic #resistance. Bacteriophage therapy represents a potentially novel approach.
2/
Phages were administered intravenously, by aerosolization, or both to 20 patients
Favorable clinical or microbiological responses were observed in 11 patients.
3/
Read 5 tweets
Jun 8
A 26-YO👩‍🦰, sexually active: 1-month of right knee and metacarpal arthralgia, tenosynovitis & pustules on her hand, developed an enlarging chest wall mass.

CT: an abscess on her chest wall, requiring drainage.
1/4

DOI: doi.org/10.1503/cmaj.2…
#IDTwitter #MedEd Image
Urine gonococcal nucleic acid amplification test: ➕ was positive,
16S rRNA with gene sequencing of wall fluid:➕for Neisseria gonorrhoeae.

DISSEMINATED GONOCOCCAL INFECTION

Ceftriaxone IV stopped after the abscess had resolved
2/4

#MedicalStudents #microbiology
Neisseria gonorrhoeae is transmitted mainly through unprotected vaginal, anal and oral intercourse
3/4

#MedTwitter #MedStudentTwitter
Read 4 tweets
Jun 7
Lactante 4 meses, dermatitis atópica, su hermana con laringitis aguda: erupción papulosa de evolución a costras en 1 día, predominando sobre placas de eccema preexistentes.

Se inician en el tronco, incluyen cabeza, área del pañal y vesículas en boca.
1/5

#pediatria #Pediatrics
PCR (para herpesvirus y enterovirus):➕para enterovirus Coxsackie A6

ECCEMA COXSAKIUM

El A6 produce también: erupción vesículo-bullosa erosiva, cuadro Gianotti-Crosti-like y rash purpúrico-petequial

✒️Martín A y col continuum.aeped.es/screens/play/5… @aepediatria #dermatology
2/5
@aepediatria El eccema coxsackium puede producir fiebre con pápulas, vesículas y costras confluyentes en región peribucal, cuello, tronco, antebrazos, pantorrillas y dorso de manos y pies.

Generalmente, una enfermedad autolimitada con buen pronóstico.
3/5

@ContinuumAEP #Pediatrics
Read 5 tweets
Jun 6
Multi-country #monkeypox #outbreak: situation update

780 laboratory confirmed cases of monkeypox have been reported to or identified by #WHO from 27 Member States across four WHO regions that are not endemic for monkeypox virus.
1/9

who.int/emergencies/di…
#Monkeypox outbreaks in endemic countries in the #African región, 2022.

1408 suspected and 44 confirmed cases including 66 deaths were reported from seven endemic countries
2/9
WHO #Risk assessment: MODERATE considering this is the first time that many #monkeypox cases and clusters are reported concurrently in non-endemic and endemic countries in widely disparate WHO geographical areas.
3/9
Read 9 tweets
Jun 6
La #OMS eleva a 780 los casos (0 muertes) de #ViruelaDelMono en 27 países (fuera de los endémicos donde se alcanzó 1.408 casos sospechosos y 66 muertes)
Más casos en:
1⃣207, Reino Unido
2⃣156, España
3⃣138, Portugal
4⃣58, Canadá
5⃣57, Alemana
1/3

rpp.pe/p/1409769
En lo que va de año, entre los países endémicos (1.408 casos sospechosos de #ViruelaDelMono y 66 muertes), la mayoría se detectó en la República Democrática del #Congo aunque también con más de una decena de contagios en Camerún, República Centroafricana y Nigeria.
2/3
Muchos pacientes de países no endémicos (no en Africa):
✔️erupciones cutáneas en zonas genitales y anales (sugiere el contacto sexual)
✔️detectados en consultas de salud sexual "involucran principalmente, pero no exclusivamente, a hombres que mantienen sexo con otros hombres"
3/3
Read 4 tweets
May 30
Niña de 5 años, araña entre las sábanas (1): fiebre de 2 días y placa eritematosa indurada en muslo con crecimiento centrífugo y una escara necrótica central (2)
¼

✏️M. Sendín-Martín y col. @HospitalUVRocio
DOI: 10.1016/j.anpedi.2020.12.005
#pediatria #Pediatrics
@HospitalUVRocio PICADURA DE LA ARAÑA RECLUSA PARDA

Las arañas del género Loxosceles o arañas reclusas o arañas violinistas debido a la morfología dorsal de su cefalotórax tienen una distribución mundial

La lesión se resolvió los días siguientes, sin dejar cicatriz.
2/4

#MedEd #dermatology
@HospitalUVRocio Las arañas reclusas parda causan lesiones necróticas a través de una enzima denominada esfingomielinasa D1. Los síntomas sistémicos incluyen fiebre o náuseas.

De forma infrecuente, signos graves como coagulación vascular diseminada o la rabdomiólisis
3/4
#IDtwitter #MedTwitter
Read 5 tweets

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