Betting for the next best thing in digital #diabetes technology:

'#AID systems & algorithms are very effective.
Unfortunately, they are used by a minority of ppl who cld benefit from them.'
-Steven Russell

#EASD2022 #dedoc°voices #nothingaboutuswithoutus @dedocORG 1/n
Betting for the next best thing in digital #diabetes technology:

'In addition to the challenges of getting hybrid #AID systems, they still require setups. They still require the user to #carbcount for meals & initiate correction boluses.'
-Steven Russell

#EASD2022 #dedoc 2/n
Betting for the next best thing in digital #diabetes technology:

'The #IletBionicPancreas pivotal trial results will be published by end Sept.' -Steven Russell

✅ Only setup needed: @PwD's weight
✅ No #carbcounting
✅ Fully automated

#EASD2022 #dedoc°voices #BetaBionics 3/n
Betting for the next best thing in digital #diabetes technology:

'The 13 wks #IletBionicPancreas pivotal trial results will be published by end Sept.' -Steven Russell

✅ 26% minority population
⬆️ +16% #TIR
⬇️ -0.5% #A1c

#EASD2022 #dedoc°voices #diabetesadvocacy @dedocORG 4/n
Betting for the next best thing in digital #diabetes technology:

'Similar results with #ControlIQ studies whereas the #IletBionicPancreas doesn't require carb counting and insulin parameters.' -Steven Russell

It looks promising ✨

#EASD2022 #dedoc°voices #payitforward 5/n
Betting for the next best thing in digital #diabetes technology:

2 faster insulins #Fiasp & #Lyumjev have:
✅ 15-25min shortened time of peak
⬇️ postprandial #BG
⬇️ mean #BG
↔️ #TIR

#EASD2022 #dedoc°voices #nothingaboutuswithoutus #diabetesadvocacy
@EASDnews @dedocORG 6/n
Betting for the next best thing in digital #diabetes technology:

'With faster insulin, we can clamp the #BG within a very narrow range.' 👇
-Steven Russell

✅ Mean BG in #T1D group: 107mg
✅ Range: 96-128mg
#TIR: 98%
✅ No hypo

#EASD2022 #dedoc°voices @dedocORG 7/n
Betting for the next best thing in digital #diabetes technology:

'Glucagon could take us further.
2 hormones are missing in #T1D:
#insulin beta cells
#glucagon alpha cells are there but no longer respond to hypo.'
-Steven Russell

#EASD2022 #dedoc°voices @dedocORG 8/n
Betting for the next best thing in digital #diabetes technology:

'#glucagon is the most important defence against #hypo ➡️ automatic microdosing of glucagon may prevent severity of hypo as it is absorbed much faster than #insulin.' -Steven Russell

#EASD2022 #dedoc @dedocORG 9/n
Betting for the next best thing in digital #diabetes technology:

7-day #IletBionicPancreas study:
Insulin only ▶️ 72% #TIR
Bi-hormonal ▶️ 79% #TIR & less hypo

'We now have a stable #glucagon analog: Zegalogue (Dasiglucagon).'
-Steven Russell

#EASD2022 #dedoc° 10/n
Betting for the next best thing in digital #diabetes technology:

'In the future, we may have glucose-responsive #insulin that only acts when the glucose is high and is prevented from acting when low.' -Steven Russell

#EASD2022 #dedoc°voices #DOC @EASDnews @dedocORG 11/n
Betting for the next best thing in digital #diabetes technology:

'Possible adjunct therapies to #AID:
✅ Pramlintide
✅ GLP-1 agonists
✅ SGLT-2 inhibitors'
-Steven Russell

#EASD2022 #dedoc°voices
@EASDnews @dedocORG 12/n
Betting for the next best thing in digital #diabetes technology:

Ideal bihormonal #ClosedLoop system:
✅ Automated #glucagon
✅ Smart #insulin
✅ Adjunct drugs

The device has been submitted to the FDA - not yet to Europe 😭

#EASD2022 #dedoc°voices @dedocORG 13/n
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More from @1derfultype

Sep 23
Are we becoming robots? #AID systems for everyone with #T1D:

'#CGM is the Archimedean point of #diabetes technology. This is when the idea of closing the loop really emerged.'
-Moshe Phillip

#EASD2022 #dedoc°voices #nothingaboutuswithoutus @EASDnews @dedocORG 1/n
Are we becoming robots? #AID systems for everyone with #T1D:

'#CGM opened our eyes to the fact that the data we used to get was very different from the reality #PwD live.'
-Moshe Phillip

So true. Connecting the red dots' never been our reality.

#EASD2022 #dedoc° @dedocORG 2/n
Are we becoming robots? #AID systems for everyone with #T1D:

'I'd like to convince you they are efficient. Automated Insulin Delivery is safe and efficient.'
-Moshe Phillip

#EASD2022 #dedoc°voices #nothingaboutuswithoutus @EASDnews @dedocORG 2/n
Read 6 tweets
Sep 20
About to start watching the inspiring advocates of the #dedoc° symposium that was held earlier today at #EASD2022 🍿

Sad I couldn't watch it live. Couldn't wait to catch up here ▶️

#nothingaboutuswithoutus #diabetesadvocacy
@EASDnews @dedocORG 1/n
I already know many happy tears will be shed listening to their inspiring advocacy work 🥲

#EASD2022 #dedoc°voices #nothingaboutuswithoutus #diabetesadvocacy #languagematters
@EASDnews @dedocORG 2/n
Dedoc° symposium, What we wish you knew and why:
'It's the 1st ever #dedoc° symposium at #EASD2022'. This is what I had in mind 10y ago - a panel of advocates at the world largest #diabetes conference.'

-Bastian Hauck, @dedocORG founder

#nothingaboutuswithoutus
@EASDnews 3/n
Read 19 tweets
Apr 5
1/ #COVID-19 et #diabete : une contamination #SARScov2 peut-elle être un élément déclencheur ?

Très long (vraiment très long) #thread 🧵 ⤵️
2/ La plupart des personnes qui vivent avec une maladie chronique sont conscientes d’être plus à risque en cas de contamination #COVID. Celles qui vivent avec un #diabete #DT1 #DT2 ou autre, savent aussi qu’une infection, quelle qu'elle soit, peut provoquer une certaine
3/ résistance à l’insuline qui augmente la glycémie, accroit les besoins en #insuline, et peut parfois engendrer une complication potentiellement fatale, le coma acidocétosique. C’est particulièrement vrai en cas de contamination par le #COVID19.
Read 32 tweets
Oct 4, 2020
[#thread] Déception à la lecture de la newsletter du @CeeD_Diabete qui paraphrase l’ANSM sur les #BouclesFermées DIY. Avec +5 ans d’expérience utilisateurs les développeurs du #DIY ont ouvert la voie aux boucles commerciales 🚀

▶️ ceed-diabete.org/blog/alerte-su…

#DIYAPS #DT1
Les #BouclesFermées commerciales ne sont pas encore disponibles en France, et le seront à un public restreint. Elles le sont depuis 2 ans dans d’autres pays. Les #DT1 ne peuvent plus attendre et construisent leur propre boucle avec du matériel marqué CE.

#WeAreNotWaiting
Comparaison faite lors d’#EASD2020 ⤵️
moyenne du #TempsDansLaCible #TIR : 90% #DIY vs 70% pour les boucles commerciales.

Inspirons-nous du DIY. Faisons avancer les choses ENSEMBLE. Réduisons les complications, couteuses pour la société et en années de vie #DT1 🚀

#DIYAPS
Read 6 tweets
Sep 25, 2020
#ControlIQ Tandem T:slim #closedloop's aim at improving #TIR. To activate Control IQ, are required:
▶️ current weight
▶️ total daily #Insulin
▶️ carb ratio
▶️ ISF
▶️ correction factors
▶️ meal bolus still required

#dedoc° #dedocvoices #EASD2020 @EASDnews #NothingAboutUsWithoutUs Image
36 wk-trial #ControlIQ in teens and adults in 2019:
▶️ #TIR +11% from 61 to 71%
▶️ major #BG improvement at night 2 to 8am
▶️ average #A1c 7% (#PwD witth A1c >6.5% improved too)
▶️ less #hypos
- Dr Marc Breton, University of Virginia

#dedoc° #dedocvoices #EASD2020 @EASDnews Image
#ControlIQ in real life for 6086 users, average age 42yo, for 6 months:
▶️ #TIR 74.9% for 180 days
▶️ consistent improvement in #BG control
- Dr Marc Breton, University of Virginia

#dedoc° #dedocvoices #EASD2020 #EASD @EASDnews #NothingAboutUsWithoutUs Image
Read 5 tweets
Sep 25, 2020
The implication of the wider spread of #DIYAPS on out-of-pocket expenses for people with #T1D- Timothée Froment on the conomic burden associated with #diabetes technologies

#dedoc° #dedocvoices #EASD2020 #EASD @EASDnews #NothingAboutUsWithoutUs Image
The amount of out-of-pocket expenses for people with #T1D depends on the limited health coverage of #diabetes technologies & supplies in most countries
- Timothée Froment

#dedoc° #dedocvoices #EASD2020 #EASD @EASDnews #NothingAboutUsWithoutUs Image
Strong link between health coverage and out of pocket #diabetes expenses. The monthly average cost is:
▶️ $39 in Germany
▶️ $502 in the US
- Timothée Froment

#dedoc° #dedocvoices #EASD2020 #EASD @EASDnews #NothingAboutUsWithoutUs Image
Read 5 tweets

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