Raj Rajnarayanan Profile picture
Oct 7 12 tweets 14 min read
Tracking #SARSCoV2 #Convergent #Lineages ( aka #VariantSoup) over time - Globally | #30DayTrends

BQ.1 (#Typhon)/BQ.1.1(#Cerberus) are currently at the top & BA.2.75.2* (#Chiron) is not far behind!

Tracker: public.tableau.com/app/profile/ra…

Updated 10/6/2022
Granular details - #VariantSoup with Convergent Mutations #30DayTrends

BQ.1/BQ.1.1 and BA.2.75.2 are heading the charts!

2/n
Tracked #Convergent #lineages are predicted to be immune evasive and bind to host ACE2 receptor better than Omicron.BA2

XBB is most immune evasive
Most BA.2.75* binds better to ACE2 receptors

Closely watched lineages - XBB, CA.1, BQ.1.1, BN.1, BR.3

3/n
#Singapore is a #XBB* hotspot (#30DayTrends)

4/n
#UnitedKingdom, #USA, #Denmark, #France, and #Belgium are BQ.1.1* hotspots (#30DayTrends)

5/n
#USA, #Singapore, #Denmark, #Austria, #Australia, #Canada are emerging BA.2.3.20* hotspots (#30DayTrends)

6/n
#Singapore is an emerging BM.1.1.1 (#Mimas) hotspot (#30DayTrends)

9/n
List of "unofficial" variant nicknames for easy social media communication

H/T @TRyanGregory

Why are we watching these lineages?



11/n
Live tracking of convergent lineages with the
@GenSpectrum #Collection54 by @CorneliusRoemer

cov-spectrum.org/collections/54

12/n

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More from @RajlabN

Oct 7
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (15-DAY TRENDS):

18.5% BA.5.2.1
15.4% BA.5.2
12.0% BA.4.6
10.3% BA.5.1
3.6% BF.10
3.2% BA.5.5
2.6% BA.5.2.9
2.6% BA.5.6
2.0% BA.5
2.0% BF.7

Tracker: tinyurl.com/mryj4uu7

#OmicronUpdates 10/06/22
1/n
Top circulating lineages (#15DayTrends)

80% BA.5*
12% BA.4.6*
2% BF.7*
1.5% BA.4*
1.3% BA.2.75*
1.1% BQ.1*
0.9% BQ.1.1*
0.3% BA.2.3.30*
0.1% XBB*

2/n
.@CDCgov updated variant proportions estimates on 9/30/2022



3/n
Read 14 tweets
Oct 6
#COVID19 #VariantDashboard - #India

Top Lineages (#30DayTrends):

BA.2.75.2 (16.1%)
BM.1.1 (10.6%)
BA.2.75.5 (9.9%)
BL.1 (8.2%)
BA.2.75.1 (6.5%)
XBB (5.3%) 👀
BM.4.1.1 (4.9%)
BA.5.2 (4.6%)
BY.1 (4.5%)
BL.2 (2.9%)
BA.5.2.1 (2.4%)

public.tableau.com/app/profile/ra…

Updated 10/05/22
Granular details - #VariantDashboard #India

Closely watching XBB recombinant lineage!
Curious case of #TamilNadu!

BA.2.75* sub-lineages are dominant in Tamil Nadu

(Previously BA.5* group of lineages were dominant)
Read 5 tweets
Oct 6
#CoronaVirusUpdates #Arkansas

First sequence of BN.1 (BA.2.75.5.1) a.k.a #Hydra is uploaded from #Arkanas

BN.1 is predicted to be both highly immune evasive and binds to host ACE2 better than circulating SARSCoV2 lineages
BN.1 (BA.2.75.5.1) stands out in the graph of immune escape vs ACE2 binding (relative to BA.2) of top circulating lineages in USA (#15dayTrends)!
AR has uploaded a BQ.1* sequence earlier in the week!

Will update #Arkansas #VariantDashboard asap

public.tableau.com/app/profile/ra…
Read 4 tweets
Oct 6
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (15-DAY TRENDS):

20.4% BA.5.2.1
13.4% BA.5.2
12.7% BA.4.6
9.9% BA.5.1
3.8% BF.10
3.5% BA.5.5
2.8% BA.5.6
2.7% BA.5.2.9
1.9% BF.7
1.9% BA.5

Tracker: tinyurl.com/mryj4uu7

#OmicronUpdates 10/05/22
1/n
Top circulating lineages (#15DayTrends)

79.6% BA.5*
12.72% BA.4.6*
1.94% BF.7*
1.59% BA.4*
1.22% BA.2.75*
1.16% BQ.1*
0.78% BQ.1.1*
0.32% BA.2.3.30*
0.12% XBB*

2/n
.@CDCgov updated variant proportions estimates on 9/30/2022



3/n
Read 14 tweets
Oct 5
Tracking #SARSCoV2 #Convergent #Lineages** over time - Globally | 10/5/2022

BQ.1 (#Typhon)/BQ.1.1(#Cerberus) is currently at the top & BA.2.75.2* (#Chiron) is not far behind!

public.tableau.com/app/profile/ra…

** aka #VariantSoup #Pentagon #ConvergentQuintet and others in social media Image
Granular details - "Convergent Quintet"

BQ.1/BQ.1.1 and BA.2.75.2 are heading the charts!

2/n Image
Tracked #Convergent #lineages are predicted to be immune evasive and bind to host ACE2 receptor better than Omicron.BA2

XBB is most immune evasive
Most BA.2.75* binds better to ACE2 receptors

Closely watched lineages - XBB, CA.1, BQ.1.1, BN.1, BR.3

3/n Image
Read 10 tweets
Oct 5
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (15-DAY TRENDS):

22.0% BA.5.2.1
13.6% BA.5.2
11.0% BA.4.6
9.9% BA.5.1
3.7% BF.10
3.5% BA.5.5
3.0% BA.5.6
2.4% BA.5.2.9
2.1% BF.7
2.0% BA.5

Tracker: tinyurl.com/mryj4uu7
#OmicronUpdates 10/04/22
1/n
Top circulating lineages (#15DayTrends)

81.6% BA.5*
11% BA.4.6*
2.1% BF.7*
1.2% BA.2.75*
1.5% BA.4*
1.2% BQ.1*
0.5% BQ.1.1*
0.3% BA.2.3.30*
0.04% XBB*

2/n
.@CDCgov updated variant proportions estimates on 9/30/2022



3/n
Read 14 tweets

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