Mike Hoerger, PhD MSCR MBA Profile picture
Dec 23, 2022 15 tweets 11 min read Read on X
In an Invited Editorial in @JAMAOnc today, my colleagues & I call for health systems to develop “Comprehensive #Pandemic Support Programs” for their most vulnerable patients.

These are our Top 10 Tips!

THREAD 🧵
jamanetwork.com/journals/jamao… JAMA Oncology article, "Variability in COVID-19 Vaccine
Tip #1: Health systems should explain to all patients that #COVIDisAirborne and is best avoided through multi-layered mitigation. Swiss Cheese model of COVID mitigation
Tip #2: Health systems should prioritize getting the most vulnerable patients vaccinated & boosted.

Offer #vaccines on-site w/the SAFEST options.

Vulnerable patients want highly-ventilated or outdoor options & high-quality (e.g., N95) masks for safety. Make it happen. Vaccination given while clinician wears an N95 outdoors
Tip #3: Health systems should test whether vulnerable patients have a good #antibody response to #vaccines (cutoffs of 5,000 or 11,500 U/mL for anti-S antibodies) to inform risk.

Consider pre-exposure prophylactics, based on the patient & the variant(s) circulating. Figures from Lee et al., discussed in our editorial. Cut offFigures from Lee et al., discussed in our editorial. Cut off
Tip #4: Health systems should help patients to sample and correctly wear free high-quality #masks (N95, KN95, KF94, FFP3).

Community-based programs have proven successful. Health systems should step up to support their most vulnerable patients.

Tip #5: Health systems should help vulnerable patients to understand the benefits & limitations of COVID testing, when to time testing, precautions to take after exposures/symptoms, and how to access #RAT and #PCR testing.

Make getting #Paxlovid easier. Headline: Paxlovid is underused.   Especially in my part of
Tip #6: Health systems should help vulnerable patients understand indoor air quality (#IAQ).

#Ventilation & filtration remove viral-laden aerosols to reduce COVID risk.

Health systems should offer concrete help w/purchasing #HEPA filters for home.

cleanairstars.com/filters/ Clean Air Stars, website
Tip #7: Health systems should be leaders in explaining to vulnerable patients how to reduce in-home spread when someone tests positive for #COVID.

Too few health systems advise on reducing in-home transmission.

BUT we have the tools!
healthyheating.com/2021.COVID.Res… Example image of tactics for reducing in-home spread of COVI
Tip #8: Health systems should support vulnerable patients by developing #LongCOVID assessment & treatment programs.

Such programs exist: survivorcorps.com/pccc

They are both underutilized & overbooked. We need more programs & less medical #gaslighting about Long COVID.
Tip #9: Health systems should support vulnerable patients by keeping a list of local businesses offering remote & #COVIDsafe options.

Many of us are doing so on the #Discord app.

Vulnerable patients want health systems to use their credibility & resources to do this. Screen shot of a Discord list of local recommendations.   He
Tip #10: Health systems should support vulnerable patients in solving the problems they face living in a confrontational, too-often #ableist world.

We offer concrete tips, such as reminding ppl masking is a healthy choice, not a political one.

While our tips focus on how health systems can help patients, our rhetorical strategy was to create tension.

If health systems get vulnerable patients into well-fitting N95s, that should foster #CognitiveDissonance when clinicians poorly mask.

Foot-in-the-door technique. "Foot in the door technique." Please read our arti
People w/#cancer are more vulnerable to COVID & long COVID, even when (wisely) vaccinated, per our article & others.

Patients w/ #hematologic cancers, late-stage cancers, or on systemic therapy (e.g., chemo) are quite vulnerable.

Today, JAMA Oncology shows that patients w/#hemocologic #cancer are among the MOST vulnerable.

It is not "virtue signaling" to mask correctly to protect the most vulnerable individuals. Photo of a hematology conference.   Today, JAMA Oncology's l
Finally, in our Invited Editorial in JAMA Oncology today, we note that "vulnerability" to COVID too often remains uncertain.

#Vulnerability is also dynamic, as an initial infection can increase vulnerability. Universal precautions remain key.

jamanetwork.com/journals/jamao… Paragraph from the article. Link in Tweet.

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More from @michael_hoerger

Jul 2
🌍Want to track COVID transmission accurately worldwide?

This PMC thread walks you through leading dashboards with information more up to date than WHO & EU directories.

🧵 1/ World map, countries with high-quality up-to-date surveillance systems shown in blue.
The Pandemic Mitigation Collaborative (PMC) Dashboard provides weekly COVID updates for the U.S., using wastewater surveillance derived case estimation models and analytic forecasting.

We have added a list of international dashboards:
🧵 2/
pmc19.com/data/index.php…Australia: NSW Health Australia Department of Health, Western Australia Austria: Federal Government of Austria City of Vienna - Regional Coron-A Consortium Austria Czech Republic: State Health Institute Czech Republic Belgium: Belgian Institute for Health Canada: Government of Canada Andrew Young's Canada Visualization C19 Resources Canada * World Health Network (WHN) Canada **
Denmark: Statens Serum Institut Denmark Europe (multi-national): EU Wastewater Observatory Finland: National Institute for Health and Welfare Finland WHN Finland ** France: French Republic Data Airborne Risk Reduction Association (ARRA) France Zan Armstrong's France Visualization COVID Weather App France (Android, IOS, or Web) Thomas Delattre's France Visualization Germany: Infection Radar Germany Bay-VOC Bavaria Region Berlin Waterworks WHN Germany **
Hong Kong: Centre for Health Protection, Hong Kong Hungary: National Center for Public Health and Pharmacy of Hungary India: Pune Knowledge Cluster of India Gujarat Biotechnology Research Centre of India Ireland: Health Protection Surveillance Centre Ireland Japan: Japan Institute for Health Security Latvia: Institute of Food Safety, Animal Health and Environment Latvia Lithuania: National Public Health Centre of Luthuania Luxembourg: Microbs Luxembourg Netherlands: National Institute for Public Health and the Environment Netherlands WHN Netherlands ** New Zealand: New Zealand Institute for...
Slovenia: National Institute of Public Health Slovenia Spain: Government of Catalonia - Regional South Africa: National Institute for Communicable Diseases of South Africa South Korea: Korea Disease Control and Prevention Agency Sweden: Pathogens Sweden Switzerland: Swiss Confederation Federal Office of Public Health ETH Zurich Switzerland WISE Dashboard U.K.: Public Health Scotland Buckinghamshire Disability Service (BuDS) U.K.  *See the numbers 1-21 along the lower left. Click on 3-6 for national and regional data. ** Click on the dropdown menu. May need to try a different web browser.
Our international directory includes official government dashboards & those developed by citizen scientists.

We exclude countries that have stopped reporting in the past 2-12 months even if on EU or WHO lists. We also exclude low-quality data from opt-in testing programs.
🧵 3/
Read 43 tweets
Jun 24
PMC COVlD Dashboard, Jun 23, 2025 (U.S.)

🔥Biggest uptick since Jan
🔥1 in 167 actively infectious
🔥>2 million weekly infections
🔥700-1,200 resulting excess deaths from weekly infections

Track transmission closer to home w/our new state & international resources 👇

🧵1/6
PMC COVlD Dashboard, Jun 23, 2025 (U.S.)

🔹With >90% probability, we have entered the 11th COVlD wave.
🔹In a room of 50 people, there is already a 1 in 4 chance of an exposure.
🔹We expect nearly 15 million infections in the next month, and rising.

🧵2/6Current Levels for Jun 23, 2025	 % of the Population Infectious	 0.6% (1 in 167)	 New Daily Infections	 287000	 New Weekly Infections	 2009000	 Resulting Weekly Long COVID Cases	 100,000 to 402,000	 Resulting Weekly Excess Deaths	 700 to 1,200	 	 Monthly Forecast	 Average % of the Population Infectious	 1.0% (1 in 97)	 Average New Daily Infections	 493300	 New Infections During the Next Month	 14799000	 Resulting Monthly Long COVID Cases	 740,000 to 2,960,000	 Resulting Monthly Excess Deaths	 5,300 to 8,800	 	 Running Totals	 Infections Nationwide in 2025	 74869000	 Average Number of Infect...
PMC COVlD Dashboard, Jun 23, 2025 (U.S.)

We continue to expect transmission to break 500,000 daily infections in the U.S. around July 9th.

This is the same prediction as last week, as the forecast was dead on. Yet, there is considerably uncertainty around this timing.

🧵3/6Longitudinal transmission, past 12 months and 1-month forecast
Read 6 tweets
Jun 17
1) PMC COVlD Dashboard, June 16, 2025 (U.S.)

Current transmission (red line) closely tracks that of summer 2023 (yellow line).

We expect to break 500k daily infections between July 9 and the end of July. Our current forecast...Year over year graph of tranmission
2) PMC COVlD Dashboard, June 16, 2025 (U.S.)

Our current forecast is a bit more aggressive, predicting breaking 500k daily infections by July 9. The 2023 trend suggests end of July.

The 95% confidence interval shows large variation. Note that...Past 12 months of transmission (U.S.) and forecast
3) PMC COVlD Dashboard, June 16, 2025 (U.S.)

Note that CDC and Biobot both had retroactive corrections to last week's data, meaning the relative "lull" will last a little longer than the uncorrected data suggested. No big news on NB.1.8.1.

All good news, but...10 pandemic waves. Soon 11
Read 7 tweets
Jun 16
1) Here's a quick example of how the federal government is censoring the best scientific research. It's not just cuts to ongoing research.

It's new grant submissions too... "No forbidden words found"
2) In January, I re-submitted a promising Covid/cancer grant to a non-federal funder. Hundreds of pages. Hundreds of hours of work. The best proposal I've submitted as a scientist.

Out of curiosity, I used Sean Mullen's Scan Assist tool to see how many banned words it had...
3) The proposal had 1,750 banned words. No big deal -- they're non-federal.

BUT I had planned to submit a smaller version to NIH this month as a "back up." Impossible!

It's not a matter of using a thesaurus or the find/replace command. The grant is on *Covid*... 1,750 banned words found
Read 13 tweets
Jun 9
1) PMC COVlD Dashboard, June 9, 2025

CDC wastewater surveillance data show transmission rising. This is our forecast if transmission growth follows typical patterns.

The high & low estimates could be thought of as optimistic & pessimistic scenarios for NB.1.8.1.Forecast graph: Rising transmission the next month
2) PMC COVlD Dashboard, June 9, 2025

Notice that current transmission (red line, lower left) tracks closely with two years ago (yellow), slightly below the median (gray), and not far below last year (orange).

Consider each of these trajectories realistic scenarios.Image
3) PMC COVlD Dashboard, June 9, 2025

All indications are that we are headed into the start of an 11th national wave in the U.S.

We could percolate near the lull point another couple weeks (fingers crossed), but that scenario is becoming less likely.Graph of 10 C19 waves
Read 7 tweets
Jun 3
1/ PMC COVlD Dashboard, June 2, 2025 (U.S.)

National COVlD transmission recently fell to its lowest levels since the pre-Delta era.

It's go-time for many who have delayed medical appointments. The situation will likely get much worse in Jul/Aug.
2/ PMC COVlD Dashboard, June 2, 2025 (U.S.)

An estimated 1 in 211 are actively infectious. Most states are "low" or "very low" per CDC.

The situation remains serious even in a relative "lull." >1.5 million weekly estimated infections to result in 600-900 excess deaths.C19 heat map
year over year graph, tracking closely with the median and past 2 years
Current Levels for Jun 2, 2025	 % of the Population Infectious	 0.5% (1 in 211)	 New Daily Infections	 227000	 New Weekly Infections	 1589000	 Resulting Weekly Long COVID Cases	 79,000 to 318,000	 Resulting Weekly Excess Deaths	 600 to 900	 	 Monthly Forecast	 Average % of the Population Infectious	 0.7% (1 in 139)	 Average New Daily Infections	 344566.6667	 New Infections During the Next Month	 10337000	 Resulting Monthly Long COVID Cases	 517,000 to 2,067,000	 Resulting Monthly Excess Deaths	 3,700 to 6,200	 	 Running Totals	 Infections Nationwide in 2025	 70132000	 Average Number of Infe...
Graph of the whole pandemic, 11th wave forthcoming
3/ PMC COVlD Dashboard, June 2, 2025 (U.S.)

By the end of the month, we forecast an increase to 450k daily infections. If NB.1.8.1 takes off, closer to 600k. If overhyped, percolating only slightly higher.Past 12 months and forecast
Read 5 tweets

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