In an Invited Editorial in @JAMAOnc today, my colleagues & I call for health systems to develop “Comprehensive #Pandemic Support Programs” for their most vulnerable patients.
Vulnerable patients want highly-ventilated or outdoor options & high-quality (e.g., N95) masks for safety. Make it happen.
Tip #3: Health systems should test whether vulnerable patients have a good #antibody response to #vaccines (cutoffs of 5,000 or 11,500 U/mL for anti-S antibodies) to inform risk.
Consider pre-exposure prophylactics, based on the patient & the variant(s) circulating.
Tip #4: Health systems should help patients to sample and correctly wear free high-quality #masks (N95, KN95, KF94, FFP3).
Community-based programs have proven successful. Health systems should step up to support their most vulnerable patients.
Tip #5: Health systems should help vulnerable patients to understand the benefits & limitations of COVID testing, when to time testing, precautions to take after exposures/symptoms, and how to access #RAT and #PCR testing.
The NIH Clinical Center drops universal masking after 5 months of protecting patients, family, & staff.
Wastewater-derived estimates indicate 2.79 million Americans are getting Covid per week AND top actuaries suggest an American dies of Covid every 3 minutes.
🔹1 in 120 actively infectious
🔹1 in 3 chance of exposure in a room of 50
🔹2.8 million weekly infections
🔹>140,000 resulting LC cases from the week's infections
🔹>1,000 deaths resulting from the week's infections
2) Watch this video to understand how we use excess death data from one of the world's largest reinsurers to estimate how this week's infections will result in >1,000 deaths.
🔹800-1,400 deaths expected to result from this week's infections (new stat, see video next Tweet)
🔹100,000+ Long Covid conditions to result from this week's infections
🔹1 in 142 actively infectious today
🧵2 of 5
PMC Dashboard, March 31, 2025 (U.S.)
This video explains U.S. COVID excess death statistics, which we have incorporated into the dashboard.
🔥109,000-175,000 people in the U.S. are expected to die as a result of COVID in 2025, based on estimates derived from Swiss Re
🔥COVID deaths expected to be on par with lung cancer in the U.S. in 2025
🔥Death data added to the dashboard
2) Full video links to learn more about COVID #ExcessDeaths in the U.S.
🔹3 million new weekly infections in a persistent "lull" of substantial transmission
🔹1 in 107 (0.9%) of the population actively infectious
🔹1 in 3 regions in high/very high transmission (16 states and DC)
PMC Dashboard, Mar 24, 2025 (U.S.)
🧵2/5
We have had a steady state of about a half million infections the past several weeks. That's over 50 million estimated infections so far in 2025.
In a room of 40-50 people, there's a 1-in-3 chance of exposure if no testing/isolation.
PMC Dashboard, Mar 24, 2025 (U.S.)
🧵3/5
There's a good chance of steady transmission the next month. Often, we'd head into a low lull about now. BUT there are no universal precautions, immunity is waning from the fall & winter 2023-24, & viral evolution looks less 'lucky.'