Thread by @iXeno

Well, with @delbigtree planning to "fact check" @PeterHotez guest spot of @joerogan ojn this weeks @HighWireTalk, I thought I'd give him some help figuring out What’s Wrong With “Dr. Paul” and his “real world data”
Select talking points to follow:

1/ Dr. Paul Thomas has presented informal data from his clinical observations.
Dr. Graven was used to lend credibility and appearance of independence but has never commented on this publicly, nor provided actual statistics, just a "P=0.05." On the nose. But what stat was used?

2/ Dr. Paul and Del Bigtree agreed on @HighWireTalk that this “Quality Assurance Project” can’t be submitted for publication, but went on to accept the data. This interview on a QA project has now be disseminate as “shocking truth.”

3/Dr. Paul & Jennifer Margulis, Ph.D. (in English) co-wrote “The Vaccine-Friendly Plan (2016, Ballantine, subdivision of Penguin-Random House).
Currently VFP is the #1 title under Vaccines at @amazon but "America's Pediatrician" just wants to share data, not sell the book.

4/The “real world data” from Paul's “Integrated Pediatrics” clinic suggest his VFD is not only safe, but had an autism rate of 1/440 compared to the "CDC rate of 1/36." Also, only 1 case of autism in the 715 non-vaxxed patients based on parent choice born into his practice.

5/This QA project is being touted as the “vaccinated versus unvaccinated” comparison study that “Vax Safety" advocates say have never been done.
But; not randomly selected and not randomly assigned. This is completely uncontrolled "association study" without satistics. #Vaxxed

6/Since I first saw this @chfund news, blogger @JeffereyJaxen & more outlets have picked up on Del’s interview where “America's Pediatrician, Dr. Paul Thomas reveals a shocking autism discovery.” Somehow the Denmark study was flawed, but Dr. Paul has the answer, but no IRB.

7/7 The phrase "deep dive" was used on both web articles on Dr Paul's "practice data" - but in the interview with @Del he claims now that they "have the IRB", researchers can do a "deep dive" into the data. But I thought that's what Dr. Graven already did. No IRB? No data, right?

@delbigtree, here is a bonus 8th tidbit from @EpiRen an actual working epidemiologist who will talk you through the rather simple steps to calculate the Odds Ratio based on the raw data "Dr Gaven" provided in his "deep dive" of Paul's clinical data. SPOILER: It was not "P=0.05"

And a bit of clean up to my error in naming the wrong Children's Fund - It is obviously RFK Jr's @ChildrensHD who has been confusing the public by pushing bad studies. @chipfranklin & @NikkiMedoro - just tagging you in on this thread in case I don't show up to work tomorrow.

@Unrollme