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Happy to announce our latest work where we combined and analysed over 280,000 genomes from the human gut microbiome: biorxiv.org/content/10.110…. A great collaboration between the teams of @robdfinn, @kyrpides, @nsegata, @PhilHugenholtz, Katie Pollard and @fstrozzi #microbiome
We generated a unified genome and protein catalogue comprising 4,644 microbial species and over 170 million non-redundant proteins, representing a comprehensive picture of the currently known diversity of the human gut microbiome 
Our analyses revealed a nice overlap between the recent large-scale datasets of MAGs from @nsegata (bit.ly/2krlJFk), our team (go.nature.com/2kw9OGq) and @kyrpides (go.nature.com/2mqEtp9), reinforcing the results from each of the original studies
This is important because over 70% of the species in our catalogue lack a cultured representative (even when considering recent culturing efforts), meaning we can only predict their genome based on the metagenomic data
Some of the species here included comprise thousands of genomes, which allowed us to explore general patterns of intra-species diversity in the gut microbiome
Alongside the paper, we are also making this resource available in a new "Genomes" section in @MGnifyDB (bit.ly/2mqx617), which includes a BIGSI-based search system to query the 4,644 species
You can also access these data in many different ways, for example via the MGnify API (bit.ly/2m5c73n), via ENA @enasequence (bit.ly/2mjoGbw) and our public FTP (bit.ly/2lWI2Dm)
