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Area-specific synapse structure in branched posterior nucleus axons reveals a new level of complexity in thalamocortical networks jneurosci.org/content/early/… - really nice, detailed work
...but I don't quite understand the claim of a "new subcellular level of complexity". There are many known examples a neuron making different types of synapses onto different target cells
Synaptic properties depends on both partners: Specification of synaptic connectivity by cell surface interactions nature.com/articles/nrn.2…
Making different synapse types onto different targets allows the same information to be communicated and transformed differently for different purposes
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Kevin Mitchell
@WiringTheBrain
'Eugenics is possible' is not the same as 'eugenics is good' @UnHerd unherd.com/2020/02/eugeni… - an interesting discussion of why we often talk past each other by @TomChivers. But...
@unherd @TomChivers One point not made is that the very idea of people having a "cold, rational, philosophical" discussion about an issue like eugenics is appalling to those for whom it is an existential issue
@unherd @TomChivers You can say as a scientist that we should be able to discuss any ideas freely, in that cold, detached way, but raising the issue of whether eugenics would "work" is like asking whether apartheid "worked"...
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Kevin Mitchell
@WiringTheBrain
Darwin had some very interesting ideas on free will:
This one seems to express the idea that the capacity for self-directedness is embodied in the physical configuration of the organism, by virtue of what its physical states mean
And that the meaning of any given state is given by the value assigned through interaction with its environment...
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Kevin Mitchell
@WiringTheBrain
Insufficient Evidence for “Autism-Specific” Genes osf.io/24gm3/ via @OSFramework
@OSFramework @ScottMyers20 @dhledbetter Oops! Forgot to tag @clesemartin! And many other co-authors not on Twitter... This paper argues against the idea of "autism-specific" genes...
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Andrew Pershing
@Sci_Officer
Here are my early thoughts on the @IPCC_CH #SROCC report.ipcc.ch/srocc/home/
The difference between RCP8.5 (high CO2, “business as usual”) and RCP2.6 (aggressive decarbonization) is striking. Under 2.6, we change for 30 years, then stabilize. Under 8.5, the changes keep coming and every year gets harder and harder.

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Thijs J. G. Ettema 🇳🇱🇸🇪🇪🇺
@Ettema_lab
Loki decloacked! biorxiv.org/content/early/… The amount of work described in manuscript represents a monumental effort, of which the importance cannot be understated! A thread.
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Surya Ganguli
@SuryaGanguli
1/ New in @sciencemagazine w/ @KarlDeisseroth lab: science.sciencemag.org/content/early/…: new opsin + multi-photon holography to image ~4000 cells in 3D volumes over 5 cortical layers while also stimulating ~50 neurons to directly drive visual percepts; data analysis and theory reveal…
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Kate Wassum 🧠👩🏼‍🔬
@KateWassum
***New paper out from our lab***

@MelissaMalvaez discovered a critical brain circuit that regulates reward learning & decision making

Here is what she found. Thread 👇

Free full text: rdcu.be/bvn4u

nature.com/articles/s4159…
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Alexis Verger
@Alexis_Verger
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'Yuki' Kamitani
@ykamit
New preprint from our lab:
Deep image reconstruction from human brain activity
biorxiv.org/content/early/…
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