Thread by @john_damianosMD

Thank you so much to @DrPraegers for having me to discuss the effects of plant-based diets on the #gut #microbiome! Here are my slides for all to see! 😃

🍅🥑🧅🍑🥦🍒🫑🍊🌶️🍎🍆🍊🫒🍓🥒🍉🥗🥝🦠

#medicine #medtwitter #diet #nutrition #GITwitter #GI #guthealth #health

Just as we do things for heart health and brain health, our #microbiome is an organ of its own (the size of a 🥭), so we need to take care of it!

The #microbiome affects almost all organ systems!

Long term dietary patterns are important contributors to the composition of the #microbiome

Dysbiosis contributes to the development and maintenance of many chronic diseases

The Western diet induces metabolic endotoxemia which stimulates the perpetuation of inflammation

The microbiota can activate pro- and anti-inflammatory metabolites via specific metabolites based on components of the #diet

Like in life, #diversity is good for the #microbiome!

Prebiotic fiber makes our friendly bugs happy and ultimately suppresses inflammation!

Two examples of downstream effects of SCFAs from fiber (gut-brain axis and immune system)

Specific plant foods support the good guys in specific ways. This is another reason why dietary diversity is good!

Associating bugs with health and disease states, and how diet manipulates this

High intake of animal protein adversely impacts the #microbiome and damages the gut epithelial barrier

High fat diet ▶️ systemic inflammation 🔥

TMAO and CVD

Switching to a vegan diet dramatically ⬇️ TMAO levels

Processed foods can promote inflammation, which is why we advise #IBD patients to minimize or avoid!

Here's my prescription for a #microbiome friendly #diet and some bonus ways to support our friendly bugs!

#GITwitter #GI #health #nutrition #guthealth

@YaleIMed @YNHH @YaleIM_Chiefs @YaleMed @YaleDigestive @Yale_LabMed @GeiselMed @DHMCVascular @dartmouth @dartmouthalumni

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