Is the field of Metabolic Psychiatry new and emerging? Actually no. There has been a long history of metabolism being known to play a role in mental illness. #metabolicpsychiatry #mentalillness (1/12)
@ChrisPalmerMD provides an excellent outline of what we knew and when in this talk on the @Metabolic_Mind YouTube Channel (2/12)
@ChrisPalmerMD @Metabolic_Mind Sir Henry Modsley said in 1879 that diabetes is a disease that runs in families with insanity. #metabolism #metabolicpsychiatry (3/12)
@ChrisPalmerMD @Metabolic_Mind In the 1930s-1950s, insulin coma therapy was the most widely used treatment for mood and psychotic disorders. #metabolism #metabolicpsychiatry #mood (4/12)
@ChrisPalmerMD @Metabolic_Mind Abnormalities in metabolic markers were first identified in patients with bipolar disorder and schizophrenia in the 1950s. #metabolicpsychiatry #bipolar #schizophrenia (5/12)
@ChrisPalmerMD @Metabolic_Mind Functional neuroimaging studies in the 1990s led to the mitochondrial hypothesis of bipolar disorder. #mitochondria #neurotwitter #bipolardisorder (6/12)
@ChrisPalmerMD @Metabolic_Mind Researchers have identified mitochondrial gene differences in patients with bipolar disorder compared to healthy controls. #metabolicpsychiatry #bipolar #genetics #mitochondria (7/12)
@ChrisPalmerMD @Metabolic_Mind There has been an explosion of research on the mitochondrial and metabolic hypothesis of bipolar disorder and schizophrenia. #mitochondria #bipolar #schizophrenia #metabolicpsychiatry (8/12)
@ChrisPalmerMD @Metabolic_Mind And as if all that wasn't evidence enough, we now have this beautiful study using Metformin for even more evidence that mental illness is a metabolic disorder. (9/12) psychiatrist.com/jcp/bipolar/tr…
@ChrisPalmerMD @Metabolic_Mind And another great study was done discussing the role of insulin signaling that lithium plays for people with bipolar disorder (10/12)
@ChrisPalmerMD @Metabolic_Mind You can find it here! @IainCampbellPhD was a coauthor. nature.com/articles/s4139… (11/12)
@ChrisPalmerMD @Metabolic_Mind @IainCampbellPhD I want you to know all the ways you can feel better! If you identify as a mental health advocate please retweet this thread! (11/12) #ketoformentalhealth #metabolicpsychiatry #brainhealthmatters

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More from @KetoCounselor

Jan 14
The Unique Regulation of Glucose and Ketosis in the Brain 🧵(1/4)
Regulatory controls are tighter in the brain than in the periphery. Glucose and glycogen regulation happens in the glia in the brain. #glia (2/4)
Ketosis can take 24-36 hours to achieve in the periphery, but the brain goes into ketosis every night. Glial glycogen stores are depleted within 6-8 hours. #ketones (3/4)
Read 4 tweets
Jan 14
A well-formulated ketogenic diet for brain health excludes grains. Let me tell you why. (1/7) #ketogenic
The effect of glutens aside, you want the full benefit of your nutrient-rich diet. You don't want to eat things that bind to the minerals you eat and make them inaccessible for your use. Like, you can do that, but what's the point? (2/7) #nutrition
Your brain needs minerals for optimal functioning. It's all about the mitochondria. And they need those minerals. Check out these key points from this important paper 👇(3/7)
sciencedirect.com/science/articl…
Read 7 tweets
Jan 13
Addressing dysfunctional brain metabolism and finding brain health comes not just from changing your fuel source but also from adequate micronutrient intake. Your brain relies on these to make energy and they play an important role in health brain metabolism. 🧵(1/8)
A role for supplements in optimizing health: the metabolic tune-up - sciencedirect.com/science/articl… (2/8)
With different environmental (chemicals, pathogens, viruses), emotional, and highly processed food stressors, we are using up a lot more micronutrients than we think. (3/8)
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Jan 13
Brain Fog comes before the criteria are met for Mild Cognitive Impairment (MCI). What are the symptoms of MCI? You might recognize them as what you are currently dealing with in your own recurrent or chronic brain fog symptoms. #brainfog #mci #mood 🧵(1/14)
You forget things more often.
You miss appointments or social events.
You lose your train of thought. Or you can't follow the plot of a book or movie. #brainfog #mci #mood (2/14)
You have trouble following a conversation.
You find it hard to make decisions, finish a task or follow instructions.
You start to have trouble finding your way around places you know well. (3/14) #brainfog #mci #mood
Read 14 tweets
Jan 12
The Bazuki Metabolic Neuroscience Initiative supported by @BaszuckiGroup means good things for mental illness and neurological disorders. This is a thread to learn more. 🧵 (1/7) #neuroscience #metabolism #metabolicpsychiatry
@BaszuckiGroup The initiative will have three arms: clinical, mechanistic, and computational, and will serve as a hub for coordinating funding and research in this area. (2/7) #brainhealthmatters #research #neuroscience
@BaszuckiGroup The initiative will also conduct its research in these three areas, including foundations, Frontiers, and Technology development. (3/7) #research
Read 7 tweets
Jan 11
Some of the brightest minds are researching in the field of metabolic psychiatry, developing multi-scale models based on principles of statistical physics. #metabolicpsychiatry (1/4)
Researchers investigate at the neuronal, glial, and mitochondrial level to understand brain function. and includes a neurovascular coupling function to link neural activity with blood flow. (2/4) #neuroscience #brainresearch
It's all about understanding how networks reorganize. They are using an optimization function to analyze fMRI data and understand the brain's activity on a large scale. (3/4) #fMRI #brainimaging #brainfunction #neuroscience
Read 4 tweets

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