Ignoring transient vision loss in right eye could have been risky for a 50-year old
1. 50-year old Mr Raj presented with symptoms of sudden onset loss of vision in right eye, which recovered in 30 minutes. It first occurred 30 days back and recurred a week back. #MedTwitter
2. As his #vision had completely recovered a month back, Raj ignored it and did not seek medical help. When it recurred for the second time, he decided to see an #ophthalmologist.
Eye check up was normal and he was referred to a #neurologist. #neurotwitter
3. On enquiry, he had complete loss of vision in right eye on both the occasions, which lasted for 30 and 20 minutes respectively. He had no headache or any other neurological symptoms.
He was taking medicines for high BP for two years.
The diagnosis was clear by now.
4. I asked for CAROTID DOPPLER test. Within two hours, Raj returned with the report. There was 80% stenosis in right carotid artery and 40% stenosis in left carotid artery.
The final diagnosis was transient monocular blindness (amaurosis fugax) due to carotid stenosis.
5. Raj was at very high risk of getting #stroke and he could have been left paralyzed, if the atherosclerotic plaque in carotid artery had ruptured and travelled to brain, thereby blocking blood supply of brain.
I referred him for urgent carotid revascularization procedure.
6. The procedure was uneventful.
Blood thinner medicines and statins were continued, in addition to his BP-lowering drugs.
7. Take home message
*Short-duration loss of vision in one eye is often due to blockage of blood supply. Blood supply to eye comes from a branch of carotid artery, which supplies blood to brain also.
*Detailed evaluation including carotid doppler should be done in such cases.
8. Carotid stenosis is present in patients with ocular ischemia in 10% of those with transient visual loss.
Those with carotid stenosis have a higher risk of stroke recurrence and should be considered for urgent surgical intervention. doi.org/10.1308/rcsann…
9. The most common cause of transient blindness in one eye is athero-thrombo-embolism from the origin of the internal carotid artery. Antiplatelet therapy is needed for all, and carotid endarterectomy is needed if carotid stenosis is >70%. doi.org/10.1080/106419…
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1. Dark chocolates are popular due to their potential health benefits (they are rich in anti-oxidants and are good for heart) and moreover, they are low in sugar content. >50% consider them as safer and healthier option (as compared to candies)
2. But there’s a dark side to this “healthier” #chocolate. Research has found that some dark chocolate bars contain cadmium and lead—two heavy metals linked to a host of health problems.
Consumer report scientists detected cadmium & lead in many dark chocolate samples tested.
3. Consistent, long-term exposure to even small amounts of heavy metals can lead to a variety of #Health problems. The danger is greatest for #pregnantwomen and young #Children because the metals can cause developmental problems, affect #brain development, and lead to lower IQ.
2. Possible physiological explanations underlying a direct role for MVPA in supporting cognition include *Acute increases in cerebral perfusion,
*Growth factor release such as brain-derived neurotrophic factor,
*Hippocampal neurogenesis.
3. Lastly, MVPA, when attained by structured exercise, involves some degree of self-motivation, planning and social interaction, which are all factors considered to be cognitively stimulating.
Canadian guidance on #alcohol consumption
(January 2023) 1. Young people should delay alcohol use for as long as possible.
2. Individuals should not start to use alcohol or increase their alcohol use for health benefits.
3. Any reduction in alcohol use is beneficial.
4. When pregnant or trying to get pregnant, no amount of alcohol is safe 5. When breastfeeding, not drinking is safest 6. Consuming no drinks is associated with better health & better sleep, 7. Three to six drinks/week raise the risk of developing breast, colon & other cancers
8. Seven or more drinks per week increase the risk of #heart disease or #stroke.
9. Each additional drink "radically increases" the risk of these health consequences.
10. Consuming one or two standard drinks weekly will likely not have alcohol-related consequences.
Low dose exercise regimen is quite effective in patients with knee #osteoarthritis (OA)
1. Patients with knee OA suffer from #knee pain, poor knee function and poor quality of life.
A recent study compared low dose versus high dose exercise regimens in people with knee OA.
2. High-dose #exercise therapy lasted for 70-90 minutes consisting of 11 exercises, whereas low dose exercise therapy (consisting of 5 exercises) lasted for 20-30 minutes.
Both were performed three times a week.
Patients were followed up at 3, 6 and 12 months.
3. Both groups improved over time, but there were no benefits of high-dose therapy in most comparisons.
However, small benefits with high-dose exercise were found for knee function in sports and recreation and for quality of life (QoL). doi.org/10.7326/M22-23…
"Burning the midnight oil" the night before exams results in poorer grades 1. It is common to see students studying late nights especially closer to #examinations. But does studying extra at the cost of missing #sleep result in better academic performance? #AcademicTwitter
2. A survey was conducted among student pharmacists to correlate sleep duration and course grades. About 300 students of pharmacy (first to third years) were included in the survey.
Reference: doi.org/10.5688/ajpe79…
3. More than half of student pharmacists obtained less than 7 hours of sleep at night during a typical school week (55%) and a large majority on the night prior to an examination (82%).
Time-restricted eating alone may not result in long-term weight loss
1. Time-restricted eating (TRE), a form of #IntermittentFasting (IF), has gained popularity for #weightloss.
However, weight loss was not seen in a recently published study with TRE. #obesity#MedTwitter
2. 547 participants (78% women, mean age 51 years, mean BMI 30.8) were followed up for 6 years.
*Mean interval from first to last meal was 11.5 hours and was not associated with weight change.
*The number of #meals per day was positively associated with weight change.
3. Total daily number of large (>1000 calories) and medium meals (500-1000 calories) was associated with increased weight over follow‐up time, while total number of small meals (<500 calories) was associated with decreasing weight.