Raj Rajnarayanan Profile picture
Apr 19 18 tweets 20 min read Twitter logo Read on Twitter
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

69.3% XBB.1.5
6.8% XBB.1.16
4.8% XBB.1.9.1
1.4% XBB.1.5.15
1.4% XBB.1.5.1
1.2% XBB.2.3
1.1% XBB.1.9.2
1.0% XBB.1.5.17

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7 Updated: 04/18/23

1/n Image
Use "Airport Surveillance" (AS) pull-down menu to easily track variant proportions Nationally or by State with or without AS sequences

Top lineages (#15DayTrends w/o AS seqs):

XBB.1.5 (73.3%),
XBB.1.9.1 (4.8%),
XBB.1.16 (3.0%),
XBB.1.5.15 (1.7%),
XBB.1.5.1 (1.4%)

2/n Image
Sequence count by US States

#NewYork, #California, #Florida, #Arizona, #NorthCarolina and #NewJersey have submitted a big share of sequences with specimen collection dates on or after 04/03/2023

XBB.1.5 is still at the top spot; followed by XBB.1.9.1, XBB.1.16, XBB.1.5.15

3/n Image
Granular details -#VariantDashboard #USA #15DayTrends

XBB.1.5* (VOI -@WHO) is still ahead of the other lineages!

4/n Image
.@CDCgov updated variant proportions estimates on 04/14/2023 (updated every Friday)

XBB.1.16, XBB.1.9.2 and FD.2 make an entry!

Prudent to start tracking XBB.1.5.13 (parent of EK.1* and EK.2*) and XBB.2.3 as well


4/n
XBB.1.16 has the potential to outcompete all other circulating lineages.

Everyone is closely watching XBB.1.16 hotspots for clues

Tracker: public.tableau.com/app/profile/ra…

5/n
XBB.1.16 is one of the fittest variant in circulation right now.. and is picking up additional mutations... "its the one to watch"

H/T @ErinMPrater @WellatFortune
@FortuneMagazine

fortune.com/well/2023/03/3…

6/n
What to know about the XBB.1.16 COVID variant causing concern in India

H/T @ingridhein @medpagetoday

abcnews.go.com/Health/xbb116-…

7/n
Predicted Immune Escape and ACE2 binding of top lineages in USA (relative to BA.2)

Bivalent boosters (OG/Omicron.BA.5) will potentially protect the boosted from getting severe disease/ hospitalizations.

Get updated if you haven't already!
public.tableau.com/app/profile/ra…

8/n
.@US_FDA amended the emergency use authorizations (#EUAs) of the @moderna_tx and @pfizer -@BioNTech_Group #COVID19 #bivalent #mRNA #vaccines to simplify the vaccination schedule for most individuals.



9/n Image
#Hospital #Capacity - (by State/Division)

All hospitalizations not just COVID-19

public.tableau.com/app/profile/ra…

10/n
#COVID19 #Hospitalizations in the #UnitedStates

>60 yr old & immunocompromised Have a good look at @CDCgov info on #Boosters!

#Ventilate Indoor spaces

Sick? --> Wear a good quality #Mask!

Hospital Tracker (by States, by age group): public.tableau.com/app/profile/ra…
11/n
Circulating recombinant lineages - USA #15DayTrends

XBB.1.5* is still the top recombinant in circulation!

12/n ImageImageImage
Status of the latest #COVID19 Wave in #NewYork

Top circulating lineages in NY (#15DayTrends)

XBB.1.5 (66.4%)
XBB.1.16 (8.2%)
XBB.1.9.1 (4.9%)
XBB.1 (3.7%)
XBB.1.5.1 (2.9%)
XBB.1.5.15 (1.2%)
XBB.2.3 (1.2%)
XBB.1.9.2 (1.2%)

13/n ImageImage
Status of the latest #COVID19 Wave in #California

Top circulating lineages in CA (#15DayTrends)

XBB.1.5 (64%)
XBB.1.16 (12.9%)
XBB.1.9.1 (4.9%)
XBB.1.9.2 (2.2%)
EG.1 (1.3%)
XBB.1.5.15 (1.3%)

14/n ImageImage
Status of the latest #COVID19 Wave in #Texas

Top circulating lineages in TX (#15DayTrends)

XBB.1.5 (70.8%)
XBB.1.9.1 (7.7%)
XBB.1.5.1 (4.6%)
XBB.1.5.15 (3.1%)
XBB.1.5.17 (3/1%)
XBB.1.16 (1.5%)
EG.1 (1.5%)

15/n ImageImage
USA Airport surveillance update #15DayTrends

222 sequences from 6 US States (#California, #NewYork, #Washington, #NewJersey, #Georgia and #Virginia) from @CDCgov's Traveler-Based Genomic Surveillance Program.

*Includes pooled swabs & Many bad QC seqs

16/n ImageImage
As COVID Tracking Wanes, Are We Letting Our Guard Down Too Soon?

"Closing up shop too early could mean we are blindsided" “You have to maintain a base level of sequencing for new variants"

H/T @DohenyKathleen @WebMD
webmd.com/covid/news/202…

17/n Image

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More from @RajlabN

Apr 21
#SARSCoV2 #VariantProportions - #USA |04/21/23

New @CDCgov #Nowcast estimates:

Top circulating lineages:

XBB.1.5 (73.6%)⬇️
XBB.1.16 (9.6%) ⬆️
XBB.1.9.1 (7.9%)
XBB.1.9.2 (2.9%)
XBB.1.5.1 (2.2%)
FD.2 (1.6%)
XBB (1%)

covid.cdc.gov/covid-data-tra…

1/n Image
Over all trends are consistent with #15DayTrends (based on sequences uploaded in the public databases)

XBB.1.5 is still at the top; followed by XBB.1.16 & XBB.1.9.1

Expect XBB.2.3 to feature in the @CDCgov dashboard soon!



2/n
XBB.1.16* hotspots per CDC #Nowcast

>5% spread in almost all regions

Region 6 estimate reads 14.4% (looks more reasonable than the previous week's estimate of 21.3% spread which looked suspect; )

3/n Image
Read 4 tweets
Apr 21
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

52.8% XBB.1.5
9.5% XBB.1.16👀
4.7% XBB.1.9.1
2.6% XBB.1.16.1👀
2.3% XBB.1.9.2
1.3% EG.1
1.2% XBB.2.3
1.2% XBB.1.5.15

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7 Updated: 04/20/23

1/n Image
Use "Airport Surveillance" (AS) pull-down menu to easily track variant proportions Nationally or by State with or without AS sequences

Top lineages (#15DayTrends w/o AS seqs):

XBB.1.5 (64%),
XBB.1.9.1 (3.8%),
XBB.1.16 (3%),
XBB.1.5.19 (1.6%),
XBB.1.9.2 (1.4%)

2/n Image
Sequence count by US States

#NewYork & #California have submitted a big share of sequences with specimen collection dates on or after 04/05/2023

XBB.1.5 is still at the top spot; followed by XBB.1.9.1 and XBB.1.16

3/n Image
Read 17 tweets
Apr 20
Tracking #SARSCoV2 lineage XBB.1.16* (#Arcturus) over time - Globally

Total Sequences : 4,837 (circulating in 37 countries)

Tracker: public.tableau.com/app/profile/ra…

Note: Recent Epi weeks are incomplete; Includes seqs from targeted & Airport surveillance
Updated:04/20/23 Image
New entrant: #Bulgaria Image
Tracking #SARSCoV2 lineage XBB.1.16.1 over time - Globally

Total Sequences : 1003

racker: public.tableau.com/app/profile/ra…

Note: Recent Epi weeks are incomplete; Includes seqs from targeted & Airport surveillance

Updated: 04/20/23 Image
Read 4 tweets
Apr 20
#VariantDashboard #India - #30DayTrends

Top lineages:

XBB.1.16 (62.8%)
XBB.1.16.1 (9.2%)
XBB.2.3 (7.8%)
XBB.1.16+NS3_V13L (4.7%)
XBB.1.5 (3.2%)
XBB.2.3.2 (3%)
XBB.1.9.1 (1.4%)
XBB.1 (1.3%)
XBB.2.3.4 (1.3%)

Tracker:public.tableau.com/app/profile/ra…

Updated: 04/19/23 Image
Granular details - #VariantDashboard #India - #30DayTrends

XBB.1.16* (76.6%) is still the dominant variant group in #India, followed by XBB.2.3* (14%)

Note: Data limited to few States that are sequencing and rapidly submitting data Image
#VariantDashboard #30DayTrends - #Delhi

XBB.1.16 (51.2%)
XBB.1.16+NS3_V13L (11.7%)
XBB.1.16.1 (9.6%)
XBB.2.3 (7.5%)
XBB.2.3.2 (4.7%)
XBB.1.5 (3.6%)
XBB.1.9.1 (2.8%) Image
Read 9 tweets
Apr 20
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

60.7% XBB.1.5
7.3% XBB.1.16👀
4.1% XBB.1.9.1
1.3% XBB.1.5.1
1.3% XBB.1.9.2
1.2% XBB.1.5.19
1.1% XBB.1.16.1👀
1.0% XBB.1.5.31

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7 Updated: 04/19/23
1/n Image
Use "Airport Surveillance" (AS) pull-down menu to easily track variant proportions Nationally or by State with or without AS sequences

Top lineages (#15DayTrends w/o AS seqs):

XBB.1.5 (65.9%),
XBB.1.9.1 (4.2%),
XBB.1.16 (3.4%),⬆️👀
XBB.1.5.19 (1.4%),
XBB.1.5.1 (1.3%)

2/n Image
Sequence count by US States

#NewYork, #California, #Arizona, #NorthCarolina and #Utah have submitted a big share of sequences with specimen collection dates on or after 04/04/2023

XBB.1.5 is still at the top spot; followed by XBB.1.9.1 and XBB.1.16

3/n Image
Read 18 tweets
Apr 18
#VariantDashboard #India - #30DayTrends

Top lineages:
XBB.1.16 (62.6%)
XBB.1.16.1 (9.3%)
XBB.2.3 (6.7%)
XBB.1.16 + NS3_V13L (4.7%)
XBB.2.3.2 (4%)
XBB.1.5 (3.8%)
XBB.1 (1.9%)
XBB.2.3.4 (1.2%)
XBB.2.3.3 (0.9%)
XBB.2.3.5 (0.7%)

Tracker:public.tableau.com/app/profile/ra…
04/18/23 Image
Granular details - #VariantDashboard #India - #30DayTrends

XBB.1.16* (76.7%) is still the dominant variant group in #India, followed by XBB.2.3* (13.5%) Note: Data limited to few States that are sequencing and rapidly submitting data Image
#VariantDashboard #30DayTrends - #Delhi

XBB.1.16 (50.8%)
XBB.1.16+NS3_V13L (11.7%) 👀
XBB.1.16.1 (10.1%)
XBB.2.3 (6.8%)
XBB.2.3.2 (5.6%)
XBB.1.5 (4.5%)
XBB.1.9.1 (3.1%) Image
Read 7 tweets

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