Thread by @RajlabN

#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

69.3% XBB.1.5
6.8% XBB.1.16
4.8% XBB.1.9.1
1.4% XBB.1.5.15
1.4% XBB.1.5.1
1.2% XBB.2.3
1.1% XBB.1.9.2
1.0% XBB.1.5.17

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7 Updated: 04/18/23

1/n

Use "Airport Surveillance" (AS) pull-down menu to easily track variant proportions Nationally or by State with or without AS sequences

Top lineages (#15DayTrends w/o AS seqs):

XBB.1.5 (73.3%),
XBB.1.9.1 (4.8%),
XBB.1.16 (3.0%),
XBB.1.5.15 (1.7%),
XBB.1.5.1 (1.4%)

2/n

Sequence count by US States

#NewYork, #California, #Florida, #Arizona, #NorthCarolina and #NewJersey have submitted a big share of sequences with specimen collection dates on or after 04/03/2023

XBB.1.5 is still at the top spot; followed by XBB.1.9.1, XBB.1.16, XBB.1.5.15

3/n

Granular details -#VariantDashboard #USA #15DayTrends

XBB.1.5* (VOI -@WHO) is still ahead of the other lineages!

4/n

.@CDCgov updated variant proportions estimates on 04/14/2023 (updated every Friday)

XBB.1.16, XBB.1.9.2 and FD.2 make an entry!

Prudent to start tracking XBB.1.5.13 (parent of EK.1* and EK.2*) and XBB.2.3 as well

https://twitter.com/RajlabN/status/1646893592084901888

4/n

XBB.1.16 has the potential to outcompete all other circulating lineages.

Everyone is closely watching XBB.1.16 hotspots for clues

Tracker: public.tableau.com/app/profile/ra…

5/n

XBB.1.16 is one of the fittest variant in circulation right now.. and is picking up additional mutations... "its the one to watch"

H/T @ErinMPrater @WellatFortune
@FortuneMagazine

fortune.com/well/2023/03/3…

6/n

What to know about the XBB.1.16 COVID variant causing concern in India

H/T @ingridhein @medpagetoday

abcnews.go.com/Health/xbb116-…

7/n

Predicted Immune Escape and ACE2 binding of top lineages in USA (relative to BA.2)

Bivalent boosters (OG/Omicron.BA.5) will potentially protect the boosted from getting severe disease/ hospitalizations.

Get updated if you haven't already!
public.tableau.com/app/profile/ra…

8/n

.@US_FDA amended the emergency use authorizations (#EUAs) of the @moderna_tx and @pfizer -@BioNTech_Group #COVID19 #bivalent #mRNA #vaccines to simplify the vaccination schedule for most individuals.

https://twitter.com/RajlabN/status/1648351465830842368

9/n

#Hospital #Capacity - (by State/Division)

All hospitalizations not just COVID-19

public.tableau.com/app/profile/ra…

10/n

#COVID19 #Hospitalizations in the #UnitedStates

>60 yr old & immunocompromised Have a good look at @CDCgov info on #Boosters!

#Ventilate Indoor spaces

Sick? --> Wear a good quality #Mask!

Hospital Tracker (by States, by age group): public.tableau.com/app/profile/ra…
11/n

Circulating recombinant lineages - USA #15DayTrends

XBB.1.5* is still the top recombinant in circulation!

12/n

Status of the latest #COVID19 Wave in #NewYork

Top circulating lineages in NY (#15DayTrends)

XBB.1.5 (66.4%)
XBB.1.16 (8.2%)
XBB.1.9.1 (4.9%)
XBB.1 (3.7%)
XBB.1.5.1 (2.9%)
XBB.1.5.15 (1.2%)
XBB.2.3 (1.2%)
XBB.1.9.2 (1.2%)

13/n

Status of the latest #COVID19 Wave in #California

Top circulating lineages in CA (#15DayTrends)

XBB.1.5 (64%)
XBB.1.16 (12.9%)
XBB.1.9.1 (4.9%)
XBB.1.9.2 (2.2%)
EG.1 (1.3%)
XBB.1.5.15 (1.3%)

14/n

Status of the latest #COVID19 Wave in #Texas

Top circulating lineages in TX (#15DayTrends)

XBB.1.5 (70.8%)
XBB.1.9.1 (7.7%)
XBB.1.5.1 (4.6%)
XBB.1.5.15 (3.1%)
XBB.1.5.17 (3/1%)
XBB.1.16 (1.5%)
EG.1 (1.5%)

15/n

USA Airport surveillance update #15DayTrends

222 sequences from 6 US States (#California, #NewYork, #Washington, #NewJersey, #Georgia and #Virginia) from @CDCgov's Traveler-Based Genomic Surveillance Program.

*Includes pooled swabs & Many bad QC seqs

16/n

As COVID Tracking Wanes, Are We Letting Our Guard Down Too Soon?

"Closing up shop too early could mean we are blindsided" “You have to maintain a base level of sequencing for new variants"

H/T @DohenyKathleen @WebMD
webmd.com/covid/news/202…

17/n