Yan Leyfman, MD Profile picture
#Medicine| Dir. & Host @MedNewsWeek| Research #Oncology #COVID19 #Immunotherapy #celltherapy #tcellrx #CART #bmtsm| About Me: https://t.co/PZG3UGoJrh & https://t.co/N0ksOsqkUj
Mar 9 6 tweets 17 min read
Thank you to our Keynote Speakers from COAST-to-COAST for their insightful presentations & to the 8,752 participants who attended @MedNewsWeek Conference in February 2022. It was a pleasure learning from everyone. I would also like to thank our great team that helped to make this event possible.
@etahmed @CParkMD @drysilay @LVento @lexyv717 @MedNewsWeek @evolusean_
Mar 9 4 tweets 7 min read
Study looking at the impact of vaccine misinformation found:

-66% of U.S. adults say they would be likely to recommend vaccinating a hypothetical 5-11 yr olds in their household who is eligible for the #Covid19 #vaccine. -39% of the vaccinated-but-not-boosted hold high levels of misinformation about the effects and safety of #vaccines
-the more that unvaccinated adults worry about getting #long #Covid, the more likely they are to say they will get vaccinated
Mar 8 4 tweets 7 min read
Study from @salkinstitute found that partial reprogramming using the #Yamanaka transcription factors (#Oct4, #Sox2, #Klf4 & #cMyc) for short periods of time:

-restored a youthful #epigenetic signature to #aging cells & extends the life span of a #premature #aging mouse model. -long-term partial reprogramming led to rejuvenating effects in different tissues, such as the #kidney & #skin, and at the #organismal level; duration of the treatment determined the extent of the beneficial effects.
Mar 8 6 tweets 16 min read
Happening now!

A discussion about Gastroenterology & the latest developments chronic diarrheal syndrome from one of GI’s global leaders-- Dr. Paul Feuerstadt from @Yale (@DrPaulGastro)

Youtube stream:

Clubhouse link: clubhouse.com/event/maWRBOp8… @lexyv717 @etahmed @LVento @drysilay @CParkMD @evolusean_ @MedNewsWeek

@Yale @YaleUniver @YaleAlumAssocNY @cpgYALE
Mar 8 6 tweets 16 min read
Happening now!

A discussion about Gastroenterology & the latest developments chronic diarrheal syndrome from one of GI’s global leaders-- Dr. Paul Feuerstadt from @Yale (@DrPaulGastro)

Youtube stream:

Clubhouse link: clubhouse.com/event/maWRBOp8… @lexyv717 @etahmed @LVento @drysilay @CParkMD @evolusean_ @MedNewsWeek

@Yale @YaleUniver @YaleAlumAssocNY @cpgYALE
Mar 8 6 tweets 14 min read
MedNews Week Conference - Infectious Disease & Gastroenterology - Dr. Paul Feuerstadt (Yale) twitter.com/i/broadcasts/1… Happening now!

A discussion about Gastroenterology & the latest developments chronic diarrheal syndrome from one of GI’s global leaders-- Dr. Paul Feuerstadt from @Yale (@DrPaulGastro)

Youtube stream:

Clubhouse link: clubhouse.com/event/maWRBOp8…
Mar 7 6 tweets 7 min read
Study from #England looking at the impact of #SARSCoV2 on #brain #pathology in 785 UK Biobank participants (aged 51–81) imaged twice found:

-brain changes in the following regions: --greater reduction in grey matter thickness and tissue-contrast in the orbitofrontal cortex & parahippocampal gyrus
--greater changes in markers of tissue damage in regions functionally-connected to the primary olfactory cortex
--greater reduction in global brain size.
Mar 7 4 tweets 7 min read
Study from @Yale looking at the association between the #Pfizer #COVID19 #vaccine and #SARSCoV2 positivity among 542 adolescents when the Delta variant of SARS-CoV-2 was predominant and within 4 months of the vaccine rollout for adolescents showed: -estimated effectiveness of the #pfizer vaccine was 91%, with 93% protection against symptomatic infections & 85% effectiveness against asymptomatic infection
Mar 6 4 tweets 6 min read
Study evaluating 29 patients with symptoms that persisted for at least 4 weeks after #COVID19 showed:

-had reported fatigue, muscle pain, dyspnea, inappropriate tachycardia, and low-grade fever
-previous #COVID19 was mild in 55% of the cases -13 patients (45%) had positive plasma RT-PCR results and 51% were positive in at least one RT-PCR sample (plasma, urine, or stool)
-18 patients (62%) received antiviral treatment.
Mar 6 4 tweets 6 min read
A study applied Mendelian randomization including >3,000 blood proteins as exposures to identify potential biomarkers that may indicate risk for hospitalization or need for respiratory support or death due to #COVID19 found: -Higher blood levels of 5 proteins associated with an increased risk of #hospitalization, need. of respiratory support or death due to #COVID19: GCNT4, CD207, RAB14, C1GALT1C1, & ABO.