Discover and read the best of Twitter Threads about #crohn

Most recents (7)

Intestinal Ultrasound
#GITwitter #MedEd

We will start with normal Normal #IUS #anatomy superficial mucosa (white) ...
#IBDtwitter

In ileocecal #Crohn’s disease, typically all bowel wall layers are involved. #IUS shows marked mural thickening, predominantly in the terminal ileum, cecum & appendix can also be involved.

🔗: ncbi.nlm.nih.gov/pmc/articles/P… Image
Bowel wall thickening is most prominent in the hyperechoic submucosal layer, representing deposition of fat and fibrous tissue as a result of chronic bowel inflammation Image
Read 56 tweets
⚠️ Esiste un legame tra #intestino e #cervello?🧠 La risposta è sì. Ma vediamola nel dettaglio. Prendetevi qualche minuto, ne varrà la pena. #Thread in arrivo. 1/17🧵
#nonsolocovid
#Depressione e #ansia accompagnano spesso chi soffre di #malattie croniche intestinali, come la #colite ulcerosa e la malattia di #Crohn, tant’è che la comunità scientifica è d’accordo da anni nel ritenere che ci sia un legame tra intestino e cervello (ancora da definire). 2/17
Su Science,il team coordinato dalla prof.ssa Rescigno (ed in collaborazione con altre unità dell'Humanitas e del CNR) ha pubblicato i risultati dello studio che apre alla conoscenza del funzionamento di una delle barriere fra circolo sanguigno e cervello, il plesso coroideo. 3/17
Read 17 tweets
1/ New paper out w/ @bnrome @Beatrice__Brown @akesselheim @PORTAL_Research examines how top-performing hospitals mark up prices on clinician-administered drugs.

🧵 below.

jamanetwork.com/journals/jamai…
2/ As of January 1, 2021, hospitals must now post payer-specific prices for all goods and services, including clinician administered drugs.

nejm.org/doi/full/10.10…
3/ Early compliance with the rule has been sluggish. See great work from @suhas_gondi @AdamLBeckman @averyofoje @JMichaelMcW

jamanetwork.com/journals/jamai…
Read 30 tweets
@MondayNightIBD @ibdnaik @SobiaMujtabaMD @ibdleuven @DCharabaty 1/29 yo M, smoker, presents with RLQ abscess w fistula to the TI; he undergoes abscess drainage & then ileocecal✂️w primary ileocolonic anastomosis. Path c/w #Crohns, margins free of disease. You see him for f/up 2 weeks post-op, What's the next ? #MondayNightIBD #Back2Basics
@MondayNightIBD @ibdnaik @SobiaMujtabaMD @ibdleuven @DCharabaty 2/ Let’s talk #Crohn’s intestinal complications
CD can present w stricturing/perforating complications
50-60% CD will develop strictures, fistulas or abscesses over time
70% require surgical✂️by 15yrs of dx
Surgery not curative, most pts will have endo recurrence 1 yr post-IC✂️
@MondayNightIBD @ibdnaik @SobiaMujtabaMD @ibdleuven @DCharabaty 3/ Natural course of CD recurrence post- IC ✂️

📌Histologic e/o CD within 3 wks post-op !!

📌70-90% pts w endo recurrence at 1 year

📌30-60% pts w clinical recurrence by 3 & 5 yrs

📌50% will need ✂️by 5 yrs

@MRegueiroMD
Read 12 tweets
Dear #NEISvoid/twitter, I am VINDICATED (&, uh, still hyper on steroids, FWIW). Awesome Sleep/RespDoc is of the educated &firm opinion (upon reviewing my hospital discharge summary, lung function test results...which the hospital still hadn’t passed on yet as of this morning? 🙄)
...that I have NOT suddenly & completely coincidentally managed to develop asthma for the first time in my life at the tender age of 39 (although he thinks it does sound like a bronchospasm cough, which is literally how I was describing it when it first started happening.
Nor do I seem to have any kind of lung problem, nor a recent past upper/lower resp tract infection). Although apparently he hadn’t received the results of either of the sputum culture tests from the hosp. I’m assuming they were boringly negative or I’d have heard by now, though.)
Read 37 tweets
Llevo 24h con el vídeo de la señora en la tienda y ya no me puedo callar más. Ignoro las circunstancias del vídeo, pero ¿sabéis quién ha cagado unas cuantas veces en la vía pública en los últimos 20 años? YO.

Es un melón desagradable, pero abrámoslo.
#EII #Crohn
Y sí, en este hilo voy a hablar de cacas y es desagradable. Pero fijaos que Igmar Bergman, el director de cine, lo explica muy bien en sus memorias. (Él Tenía Colon Irritable)
Somos varios cientos de miles de personas con EEI o colon irritable pero también cualquiera con una gastroenteritis, con una indigestión. Nos puede pasar a todos. Y sí, normalmente hay un baño a mano.

Hasta que un día no lo hay.
Read 21 tweets
Hey! I have some thoughts on the paper below that attempts to position #ME/CFS as an “autoimmune disease” by associating 2 SNPs with very small odds ratios to differences b/t infectious & noninfectious disease onset (OR=0.54 & OR=0.64): frontiersin.org/articles/10.33…
2/ The team didn’t study the #ME/CFS immune response itself, but instead measured several common #SNPs associated w/ certain “autoimmune” conditions in their ME/CFS subjects. For example SNPs in the gene PTPN22 (connected to #Crohn’s, type 1 #diabetes etc)
3/ PTPN22 is a gene that, in simple terms, plays a role in regulating B and T cell activity. It’s actually just a gene that impacts the immune response (there doesn’t HAVE to be anything “autoimmune”-inducing about PTPN22 activity)
Read 10 tweets

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