Discover and read the best of Twitter Threads about #ihcpath

Most recents (5)

A mini case: sections from the wall of the gallbladder with the following diagnosis 🎯
Questions in the thread...
#pathology #IHCpath
Q1: How do you interpret the p53 IHC stain? (hint: if you say "positive" then I failed as a teacher 😀😱)
Q2: In what other instances do you perform a p53 IHC?
It turns out that it is not a clear cut case in the provided pictures...AIS extending in Rokitansky-Aschoff sinuses has to be considered... not a gallbladder guy 😀 At the same time I would have a hard time signing out an AIS extending in RA sinuses diagnosis...
Read 30 tweets
30♀️ posterior chest wall mass. Good example of this entity. IHC in next tweet. #dermpath #pathology
#IHCpath: CD4 is also a myelomonocytic marker, so weak staining is expected in macrophages. Only strong CD4 positivity is counted as genuine for T-cells.
Full #IHCpath:
➕ Pan T-cell markers (CD3, CD2, CD5, CD7), CD8, perforin, TIA, beta-F1 (TCR beta)
➖ CD4 CD30 CD56
Read 6 tweets
#GUpath puzzler time!
(for those of you familiar with this case, please keep 🤫!)

middle aged M found to have bilateral breast enlargement. Work-up revealed elevated serum PSA. MRI-guided prostate biopsy done of abnormal area seen on imaging.

my DDx:
▶️Gleason 5+5 prostatic adenocarcinoma (for all new bx cases, I always do confirmatory prostate #IHCpath)
▶️plasmacytoid urothelial carcinoma
▶️signet ring GI tract adenocarcinoma
▶️metastatic lobular carcinoma
not shown but negative were:
NKX3.1/PSAP, CK20, uroplakin2
Read 9 tweets
Are you new to Twitter? Are you a pathology resident or a pathologist? Are you wondering what to tweet about or where to start? This brief tutorial is for you. Pathology on Twitter is awesome 👍🏾❤️✅

#Tweetorial = Tutorial of tweets

#pathtweetorial = Pathology version
First step, check out this awesome guide to social media for newcomers. SUPER useful.…

It had great tips, like this one: ALWAYS include a picture of yourself on your profile. He’s right: please do it NOW! It’s essential. Just use a selfie 😊
Follow a few pathologists. Use this handy guide created by @RoseannIWu to begin with, and then just follow people whose tweets you like. Following is a friendly gesture on Twitter, and conveys that you are interested that person’s tweets.
Read 27 tweets
Tweetorial on carcinoid tumor of the lung. I’ll add to it little by little every week 😊

#pathology #pulmpath

Carcinoid tumor is the lower grade end of the spectrum of neuroendocrine tumors in the lung.

Caution: lung terminology is different from GI tract terminology
In the lung, the terminology is
✴️ Typical carcinoid tumor
✴️ Atypical carcinoid tumor
✴️ Small cell carcinoma
✴️ Large cell neuroendocrine carcinoma

We don’t terms such as “well differentiated NET” because...this is #pulmpath and we are special 😜
Carcinoid tumors are very similar on H&E to low grade NE tumors in the GI tract or pancreas. Nesting, odd patterns, bland cytology, granular chromatin (“salt and pepper”)

Read 16 tweets

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