, 16 tweets, 11 min read
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Today in CRISPR
brief tweet thread from researcher behind this @davidrliu
@davidrliu reaction from jaded fellow genome engineer
@davidrliu Long person profile of Liu from last year by Ryan "Science Boss" Cross, who has a knack for hero stories. cen.acs.org/biological-che…
@davidrliu I've gotten a bunch of blank stares when I try to point out the personal fortunes being made in CRISPR improvements. But blank stares don't stop me!

From the Beam Therapeutics S-1. Estimating individual scientist stake worth $50 million pre-IPO
@davidrliu A Harvard Professor I guess has 1 day a week free for consulting. There have been approximately 170 fridays since base editing first published in May, 2016. $50 million divided by 170 is $294,117 a day, not considering other startups.

Good work if you can get it!
@davidrliu Here is the S-1 for Beam Therapeutics, a base editing company (and a little prime editing, too) Full of interesting info. sec.gov/Archives/edgar…
@davidrliu and a link to the Nature paper in which the scienctific result is summarized. c/o @jason_pontin
@davidrliu @jason_pontin can't access this story but gets into weird overlap between two companies Beam and Prime. Simple answer is probably same venture funds (ARCH and F-PRIME) behind both companies.
@davidrliu @jason_pontin a back-handed compliment from Tweet-master and tastemaker @EricTopol
@davidrliu @jason_pontin @EricTopol voice of reason from inside the machine, aka another gene editing lab at Broad.
@davidrliu @jason_pontin @EricTopol And if you want the "prime editor" follow the link below.

It's practically one-click shopping at @addgene

@davidrliu @jason_pontin @EricTopol @Addgene Significant comment thread characterizing Nature publication (a rush job, btw, published early without final editing) as part of a financially motivated PR operation.
@davidrliu @jason_pontin @EricTopol @Addgene A Nature reviewer defending decision to accept this paper. Not really in question since it's super cool. But I guess overt enthusiasm now must be qualified, questioned, checked all around.
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