I've been asked how I'd respond to #COVID right now:

a THREAD:

5 goals:

1) See curve: deploy tests efficiently
2) Flatten curve: Reduce transmission
3) Prepare for curve: Increase healthcare capacity
4) Catch curve: Contact trace below a threshold
4) Save livelihoods

1/
GOAL #1: SEE CURVE -

We don't have good visibility for 2 reasons:

a) our tests are being used mainly on ppl who already presumptive(+) because we're using them at point of care for sick pts.
b) there's a huge gap btwn when ppl are infected & when we get their test outcomes

2/
So instead of using tests at point of care when it doesn't change management:

1) I'd be saving 5-10% of our #COVID tests to deploy in a small representative sample of the population to better understand the spread of disease, and the burden that's on its way

3/
2) I'd screen every responder/provider on the frontlines of #COVID-care by testing at 5-day intervals. They'd be isolated if (+) so not to spread. Not a perfect screen, but better than no test or symptomatic tests.

3) Most tests would deploy at triage in goal 3 (see tweet 12)
4/
The random sample tests may sound like a waste of resources.

But they're CRITICAL: they help to model where the disease is headed, which allows us to "skate to where the puck is going," rather than just where it is right now.

That way, we're not constantly catching up.

5/
GOAL #2: FLATTEN CURVE -

I agree w/ "Stay at home" orders.

Would add:

1) require curbside protocols + no touch payment (online/phone) + social distancing workplace rules

2) require gas stations to wipe stations between customers

6/
I would also set a clear guideline for a phased let-down of #socialdistancing protocols as we meet certain points on the epidemic curve on the way down--creating a transparent, science-based answer to "when are we done with this" that the community can track and understand

7/
GOAL #3: PREPARE FOR CURVE -

The whole point of #SocialDistancing is to reduce the peak of the crest of #COVID patients. But the other thing we have to do is INCREASE the # of patients we can care for.

That's the whole point here. We have to PREPARE for the rush.

8/
At BEST, that means setting up an alternative #COVID-care system.

In every major metro + some rural communities, I'd ID a hotel, a dorm, or convention center to start preparing as a hospital now.

No one in the state should be more than 1 hr from a #COVID-care facility.

9/
That's where I'd be sending all the #COVID patients. There, a team of MDs/NPs/PAs would oversee a team of folks trained specifically to manage #COVID19 patients.

Could train EMTs, MAs, and other health pros. If well managed, a few MDs/NPs/PAs could manage many others.

10/
How to decide who goes to #COVID-care? An algorithm and a system of triage centers in front of every ER + urgicare.

First, set up triage centers to segregate folks into the usual healthcare system (for non-COVID) vs. the #COVID19 system

11/
Second, create an algorithm to ID #COVID probability. Using temp, # of COVID exposures, & chest x-ray/CT result--calculate probability score

For very high/low #COVID probability, no test.

Test mid-range probability.

All high probability & (+) patients go to #COVID-care.

12/
Segregating #COVID has several advantages:
1) We don't overwhelm usual healthcare system
2) We reduce contamination of COVID(-) sick in the usual system
3) We concentrate where we send COVID resources (#PPE, #ventilators) to facilitate logistics

13/
Resource procurement for #COVID-care is key. First, #POTUS needs to activate #DefenseProductionAct, which appears to be happening now for #ventilators.

But we also need it for #PPE and #tests.

Most of my messaging/time would be focused on getting resources to COVID-care

14/
GOAL #4: CATCH THE CURVE

It's a misnomer that we can't "contain" #COVID19. We just can't contain it NOW. Once case # falls, contact tracing/containment can begin again.

Along w/ transparent easing of #SocialDistancing as cases fall, I'd ramp containment up, a new phase.

15/
We'd need to start stockpiling tests & training up a large staff of contact-tracers beforehand to be ready to contact-trace at scale once case # falls below a certain number. That would require us to contact-trace all new cases beyond a point on the epi curve.

16/
It would mean a new strategic deployment of tests vs what I discussed above, focusing on testing contacts of cases who aren't already recovered (and presumed immune--though need more data on this point).

Would enforce isolation for all exposed & (+) so no rebound case jump

17/
GOAL #5: SAVE LIVELIHOODS:

Along w/ resources, I'd be spending a lot of time lobbying for relief on the economic front.

That's full UBI, waived healthcare costs, small business grants.

That's holding corps accountable for lost jobs/broken bargaining agreements/buybacks.

18/
I'm grateful to the state & local public officials on the front lines rn. I wish I were there with you. I can only imagine the stress & sleepless nights. Thank you - you're heroes.

I hope this can be a helpful resource from one epidemiologist/former health director.

19/19
AND - gaming this from the luxury of my #quarantine is SUPER different than doing it real life. SO I very much appreciate that, as @MikeTyson said:

"Everyone's got a plan, until they get punched in the mouth."

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More from @AbdulElSayed

Jul 8, 2021
What I wish people understood about the #DeltaVariant is that it's not the same old COVID.

Even if you've had COVID before, data suggests that this variant's figured out how to evade your immune response.

We should probably stop calling it COVID-19 & update to COVID-21.
Lemme clarify a bit: it’s not that vaccines don’t work against #Delta, there’s good evidence to suggest that in full doses they do.

It’s that NATURAL immunity is less protective.
nature.com/articles/s4158…
One of the main points used to argue against being vaccinated is that natural immunity is enough.

And though natural immunity has conferred against some degree of immunity against other variants, available evidence suggests it confers less against #delta
Read 4 tweets
Dec 20, 2020
Awful take, habibi.

Tell me @NateSilver538, what’s “actual science”?

Political polling is in shambles, why don’t you stick to that and let “actual” scientists handle this, mmkay?
habibi, what’s actually happening is that you’re just arrogant enough to misinterpret models you don’t understand & write whole damn tweet thread about it. And you forget this isn’t sports or politics. Trust matters here, & you’re undermining it out of ignorance/arrogance.
So while we’re at it, take some notes: predictive modeling, which you do, is not the same as causal modeling, which we do.

We don’t just throw a bunch of variables into a model to maximize fit. We ask how variables may explain impacts of other variables.
Read 6 tweets
Jul 22, 2020
When you read #COVID19 headlines like this, the key takeaways should be that:

1) we’re not testing enough
2) we’re testing the wrong people
3) asymptomatic & low symptomatic spread are a big issue

1/
statnews.com/2020/07/21/cdc…
Our lack of testing has been a consistent problem (nevermind what the politicians tell you) since day 1.

But it’s also about *who* gets a test. A test is only as good as the info it tells you. So you don’t want to use it to tell you something you already know.

2/
For example, if I told you I had a test to tell you your eye color, would you take it? No. Because it doesn’t tell you anything new.

But testing strategy in the US has been used this way too.

Especially early on, but even now, we mostly test symptomatic ppl w/ exposure.

3/
Read 6 tweets
Jul 21, 2020
Fascism is a word so often misused, that it immediately elicits eye rolls from serious ppl.

But it has a meaning: ultranationalist, dictatorial gov’t that deploys fear of the other, both inside & outside the nation, to consolidate power.

Trump is accelerating fascism.

1/
Think about the way Trump talks about #BLM protests as an “anti-American” Force, not out to promote racial equality, but to tear down American “heritage.”

His deployment of CBP paramilitary on the streets in #Portland is a profound escalation acting on that narrative.

2/
Consider the fact that he continues to call #COVID19 the “China virus” and stoked conspiracies that it had been developed in a lab in Wuhan to reinforce the narrative that they are the enemy abroad.

3/
Read 20 tweets
Jul 19, 2020
A thread of @realdonaldtrump quotes about #Coronavirus in chronological order for context the next time he calls #DrFauci "alarmist":

1/30 - "We only have five people. Hopefully, everything’s going to be great."

2/2 - "We pretty much shut it down"
2/10 - "Looks like by April, you know, in theory, when it gets a little warmer, it miraculously goes away."

2/24 - “The Coronavirus is very much under control in the USA."

2/26 - “When you have 15 people...that’s a pretty good job we’ve done.”
2/28 - "Now the Democrats are politicizing the coronavirus...And this is their new hoax.”

3/6 - "Anybody that wants a test can get a test."

3/10- "we’re doing a great job with it. And it will go away. Just stay calm. It will go away"
Read 7 tweets
Jul 13, 2020
No, scientists & doctors didn't "lie" to you about #masks.

To think so requires a fundamental misunderstanding of science & public health policy.

Scientific knowledge changes. Public health policy changes with it.

Mask policy is an example.

A thread:

1/
Science is not a body of knowledge. It doesn't *say* anything.

Science is a process.

We propose hypotheses about how something works in the world, then use experiments that try to disprove those hypotheses. If we can't disprove them, we assume them to be true--for now.

2/
The novel #Coronavirus is "novel" because it only emerged in humanity at the end of last year. Obviously, that's not a lot of time to study & understand this virus.

When it first emerged, the science community reasonably inferred it would behave like other coronaviruses...

3/
Read 10 tweets

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