3/ "There is a pressing and urgent need for action. COVID-19 infections and deaths recently reached record levels. The roll-out of vaccines that started out in December rocky and slow is now improving, but it will be months before most of the population is vaccinated."
4/ " In the meantime, more transmissible variants are projected to become the dominant strains by March and may pose significant challenges to the efficacy of first-generation vaccines and monoclonal antibodies."
5/ "While COVID-19 infections and deaths have started to decline in recent weeks, they remain at a very high level and, unless strengthened precautionary measures are implemented, the new variants will likely bring an explosion in new infections."
6/ "Stronger protective measures are needed immediately to limit exposure and transmission of the SARS-CoV-2 virus to control and end the COVID-19 pandemic."
7/ "For many months it has been clear that transmission through inhalation of small aerosol particles is an important and significant mode of SARS-CoV-2 virus transmission. The gravity of this problem was emphasized this week by an editorial in the journal Nature."
8/ "Numerous studies have demonstrated that aerosols produced through breathing, talking, and singing are concentrated close to the infected person, can remain in air and viable for long periods of time and travel long distances within a room and sometimes farther."
9/ "Gatherings in indoor spaces without adequate ventilation place participants at particularly high risk, an important component of which is driven by asymptomatic and pre-symptomatic viral shedding of infected individuals."
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1/x Just can't shake my disappointment in yesterday's #CDC school opening guidelines: "Operational Strategy for #K12 Schools through Phased Mitigation"
3/ So many lines of thought to follow, but I will direct you to short thread yesterday by @CorsIAQ for a good summary. The gist is simply that the #CDC guidelines leave out some of the most important, obvious help b/c they ignore the airborne component.
2/ "In times when classes were conducted with windows and door closed, the aerosol concentration was reduced by more than 90% within less than 30 min. when running the purifiers (air exchange rate 5.5 ACH). The reduction was homogeneous throughout the room ..."
[note log y-scale]
3/ Figure 3: Highly reproducible reduction in aerosol particle concentration [uCPC] in a closed classroom without air purifiers (blue line) and with 3 or 4 air purifiers operating at speed 3 or 4 (max).
1/ You've surely seen constant recent messaging & articles imploring you to improve quality of both #mask fit & filtration, in part b/c of worrying COVID variants.
Good news that the #CDC is catching up w/ those messaging efforts w/ updated guidance today.
3/ One good example summarizing the new #CDC guidance changes on masks, w/ helpful infographics, interviews, and short video w/ CDC chief Dr. Walensky.
This is why research & #scicomm now about virus transmission is so critical
"We’re going to have to be in a world that is more thoughtful about protecting ourselves from respiratory infection than we have ever had to be before.” Dr. Bloom, @HarvardChanSPH pri.org/file/2021-02-0…
(Starting at 2:31): “This is a global infection. A mutant or variant anywhere is a threat everywhere. And so we can’t be complacent and say because hopefully we start to do well by summertime in the US we will not be invaded by a new variant. So we really have to ..."
".. continue public health measures: wearing masks, reducing opportunities for spread, and being very careful, because even with vaccines, they’re not perfect, no vaccine has ever been perfect. ..."
1/ In context of extra precautions against new COVID variants, some new questions pop up about #masks.
Article by @cwarzel@zeynep asks/answers some good questions to start. Other thoughts in a 🧵, e.g. N95s, fit (Tw7+ ⬇️), when to replace (Tw25 ⬇️), etc. nytimes.com/2021/01/29/opi…
2/ Countless recent articles w/ interviews from relevant experts imploring people to still take mask-wearing & overall airborne COVID health seriously.
1/ Public admission by @mvankerkhove of #WHO that COVID transmission "goes through the air" is a *huge* turn-around from strong, incorrect statements to the contrary.
Strikes me as significant, even if subtle & played off as "we knew all along."
2/ Earlier messages #WHO put out were blatantly wrong & dangerous ⬇️.
Many scientists globally have been working tirelessly to pressure @WHO to retract dangerously misleading statements like this & adequately educate that #COVIDisAirborne.
3/ Again, messaging efforts by WHO are critical b/c of their exposure & reach. By openly saying COVID isn't in the air & having press conferences w/o masks, have been undermining efforts to #MaskUp & prevent spread.