#JNJ Vaccine Cerebral Venous Sinus Thrombosis Surveillance🧵after @CDCgov #ACIP (for now ...):
1⃣Watch for symptoms like headache, aphasia, paresis, papilledema, seizure, mental status changes
2⃣High-risk groups *seem* to be young women (~20-50), 6-20 days after #JNJ vaccine
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1⃣Watch for symptoms like headache, aphasia, paresis, papilledema, seizure, mental status changes
2⃣High-risk groups *seem* to be young women (~20-50), 6-20 days after #JNJ vaccine
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https://twitter.com/amarkelkar/status/1382428822268694535
3⃣True #CVST event rate is TBD (as is the true background rate)
4⃣PF4 IgG ELISA in all patients for screening (#publichealth reporting) & management (avoiding heparin if positive)
5⃣Consider IV steroids & IVIg for thrombocytopenia
#HemeTwitter
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4⃣PF4 IgG ELISA in all patients for screening (#publichealth reporting) & management (avoiding heparin if positive)
5⃣Consider IV steroids & IVIg for thrombocytopenia
#HemeTwitter
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6⃣Report any suspicious events to #VAERS vaers.hhs.gov/reportevent.ht…
7⃣Remember that these are RARE events and the proposed cause of #VITT remains theoretical. This pause is proof that the safety/surveillance system works!
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7⃣Remember that these are RARE events and the proposed cause of #VITT remains theoretical. This pause is proof that the safety/surveillance system works!
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8⃣🧵the 🪡 on Thrombotic Thrombocytopenia ... There's a LOT to consider, but we should not forget the harms from a long pause on #JNJ vaccines, especially for those who cannot travel for multiple doses or can access a clinic with an appropriate freezer, and #vaccinehesitancy.
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9⃣#mRNA vaccines remain highly safe and effective!
🔟Side Note: Maybe it should be called adenovirus vaccine-related thrombotic thrombocytopenia (AVRTT) given this was seen in both #JNJ and #AstroZeneca vaccines and NO #mRNA vaccines. #VITT is too broad!
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🔟Side Note: Maybe it should be called adenovirus vaccine-related thrombotic thrombocytopenia (AVRTT) given this was seen in both #JNJ and #AstroZeneca vaccines and NO #mRNA vaccines. #VITT is too broad!
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And there's much more to come on this topic from @US_FDA @CDCgov @HHSGov #ACIP and more ...
6/fin
6/fin
https://twitter.com/amarkelkar/status/1382446055455854592?s=20
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