Thread by @KrishanaSankar

Updated guide from the @COVIDSciOntario to Vaccine-Induced Immune Thrombotic Thrombocytopenia #VITT Following Adenovirus Vector COVID-19 Vaccination!
Thank you for this lay summary! @MPaiMD
Key takeaways 🧵⤵️ 1/ #science #MedTwitter #scicomm #COVID19 #COVID19Vaccine

https://twitter.com/MPaiMD/status/1390775799041691649

▶️ Blood clots can occur 4 to 28 days post 💉 & associated w/ ⬇️ platelets
▶️ These clots...are more aggressive and are more likely to cause death or severe disability...
▶️ Rate of VITT in Canada has been estimated to be ~1/ 100k doses 2/

Re: contraindication: It may be possible... people with a history of HIT or CSVT w/ ⬇️ platelets are at ⬆️ risk of VITT; they should receive an mRNA vaccine (Pfizer or Moderna) rather than an adenoviral vector vaccine. 3/

You should speak to a health care professional if you have unusual or severe symptoms after any COVID-19 vaccine. If you experience the following symptoms that start between 4 and 28 days after 💉, it might indicate that you have VITT: list here on website 4/

If you have severe symptoms such as those listed [on the website], you should go to the nearest ER immediately. If you have other symptoms that are not severe, you can discuss them (virtually or in-person) with your primary healthcare professional 5/

Health care professionals and scientists in Ontario have been working with experts in Canada, and around the world, to better understand VITT. 6/

There have been > 1.1M #COVID19 cases of diagnosed in Canada, COVID-19 has killed > 24,000 Canadians, about 1 in 100 Canadians who get COVID-19 end up needing intensive care. 7/ #COVID19 #COVID19Vaccine

The AstraZeneca/COVISHIELD and Janssen/Johnson & Johnson vaccines are both effective at reducing hospitalization and severe illness from COVID-19, and at reducing the chance you could pass the SARS-CoV-2 virus on to others. 8/ #COVID19 #COVID19Vaccine