Clinical Case for junior #doctors and residents
17-year old girl, 1 year history of imbalance while walking, sways to either side. Tendency to fall while washing her face. Hearing impairment for 6 months. No positive family history
Diet: Pure #vegetarian
#MedTwitter #neurotwitter
Patient was asked to do tandem gait
Patient was asked to stand with feet close together and eyes closed.
What are the signs shown? Differential diagnosis? Tests needed to confirm diagnosis? Treatment plan?
Thank you everyone for answering, most of the answers are correct and accurate. MRI Brain was normal. MRI Spine showed classical features of SACD. NCS showed sensori-motor axonal neuropathy. Vitamin B12 level was very low (40 pg/ml). I started her on vitamin B12 injections.
Hearing loss may occur in B12 deficiency, slightly more commonly in children and elderly. Considered Friedreich ataxia, but the clinical/imaging features were more in favor of SACD due to B12 deficiency. Patient showed clinical improvement with B12 therapy.

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More from @hyderabaddoctor

Nov 16
Brain #stroke caused during cold water bath in a 68-year old person with High BP

1. Winters are here and many people need to take bath in cold water. #Cold water #bathing can also be a part of cultural ritual. It is safe; however, in some cases; it can lead to serious diseases.
2. Here, I am sharing my experience of treating a person with stroke (which he suffered during cold water bath). 68-year old man was brought with a history of right-sided weakness and inability to speak for 26 hours.
#MedTwitter #neurotwitter #internalmedicine
3. Symptoms started within minutes of him taking dip in a holy river as part of cultural ritual. He was previously well except for #hypertension, for which he was taking medicines. He was initially treated at a local hospital and referred one day later as he did not improve.
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Nov 14
#diabetes and #Neurology
1. Peripheral #neuropathy can be the first manifestation of diabetes. 50-70% of diabetics suffer from neuropathy. Pain and burning sensation of feet are common symptoms. Numbness of feet can predispose to ulcer formation.
#WorldDiabetesDay #Medtwitter
2. Diabetes is a common risk factor of #stroke, seen in 30% of stroke cases. Diabetes leads to poorer outcome in stroke patients- longer length of hospital stay, higher risk of complications, higher risk of death due to stroke and greater disability in stroke survivors.
3. Diabetes is associated with higher risk of dementia including Alzheimer's disease. The risk of mild cognitive impairment (MCI) and conversion of MCI to dementia is higher in diabetics. Longer duration of diabetes and uncontrolled diabetes further increase the risk of dementia.
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Nov 12
How I (a #neurologist) helped a student pass in #Mathematics, which his Mathematics teacher couldn't manage

1. A 15-year old boy was brought to my clinic by his parents asking for some "pill" that would improve his interest and skill in mathematics, enabling him to pass exams
2. He was a bright class 10th kid doing well in all the subjects except in mathematics. His scores were 85-90% in other subjects, with <30% in mathematics. This appeared odd to me. On enquiry, the boy told "my mind switches off when solving complex mathematical problems".
3. The boy continued "my mind keeps on lapsing into absent-mindedness several times during exams" and "before I realize- the time is up". As per his teachers & parents, his answer sheet had many areas of ineligible scribbling. The initial part of answer would be correct though.
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Nov 11
Relationship of #distance #run per week to coronary #Heart disease risk factors

1. Guidelines recommend 30 minutes of vigorous #exercise on most days, if not all days. What is the effect if one exceeds these limits? Is it beneficial or harmful?
#running #fitness #marathon
2. Compared with runners who ran less than 16 km (10 miles) per week, long-distance runners (≥80 km/wk) showed:
#2.5 times higher prevalence of HDL>60 (protective against heart disease)
#50% reduction in hypertension
#>50% reduction in need to BP or cholesterol lowering drugs
3. Estimated age-adjusted 10-year coronary heart disease (CHD) risk was 30% lower in runners who averaged more than 64 km/week than in those who averaged less than 16 km/week (42 vs 61 events per 1000 men).
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Nov 11
What can patients do to lower #cholesterol levels, if they can not take #statin due to any reason?

1. They can take #garlic and #lemon juice, if statins are contraindicated or causing any #adverse effects such as myalgia or muscle weakness.
#MedTwitter

doi.org/10.4103%2F2008…
2. High cholesterol level is a risk factor for stroke and heart attacks. Statins are commonly prescribed drugs to lower cholesterol levels. However, some patients can not take statins due to adverse effects such as muscle pain and muscle weakness.
#Diet #nutrition #healthydiet
3. In a study, 20 gram of raw garlic and one tablespoon of lemon juice was given daily for 8 weeks in people with high chol. Total cholesterol reduced by 41 mg/dl, LDL cholesterol reduced by 30 mg/dl and BMI reduced by 1.6. (Ref: International Journal of Preventive Medicine 2016)
Read 4 tweets
Nov 10
Correlation between resting #heart rate (HR) at admission and long-term #Survival in patients admitted with #stroke
1. High resting HR is a risk factor for stroke and death. In a recent study, patient's HR at admission after stroke was correlated with long term survival & death. ImageImageImage
2. Compared with the reference group (mean heart rate < 60 bpm), risk of #death was 23% higher for mean heart rate 60–69 bpm, 74% higher for mean heart rate 70–79 bpm, 116% higher for mean heart rate 80–89 bpm, and 183% higher for mean heart rate ≥ 90 bpm.
#MedTwitter
3. Compared with the reference group (mean heart rate < 60 bpm), the risk of cardiovascular death was 18% higher for mean heart rate 60–69 bpm, 57% higher for mean heart rate 70–79 bpm, 98% higher for mean heart rate 80–89 bpm, and 136% higher for mean heart rate ≥ 90 bpm.
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