Thread by @RajlabN

#COVID19 #VariantDashboard - #UnitedStates

Interesting tug of war between BQ.1.1 & XBB.1.5

TOP lineages (#15DAYTRENDS):

27.0% XBB.1.5 👀
14.7% BQ.1.1
8.4% BQ.1
4.1% BQ.1.22
3.9% XBB.1
2.2% BQ.1.1.4

Tracker: tinyurl.com/mryj4uu7

#OmicronUpdates 12/31/22

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Sequence count by US State

New York has submitted a lion's share of sequences with specimen collection dates in the last 15 days.

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Granular details -#VariantDashboard #USA #15DayTrends

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.@CDCgov updated variant proportions estimates on 12/30/2022 (updated every Friday)

Several BQ* are circulating at >1% especially BQ.1.22 is a good candidate to be included in CDC's Nowcast estimates next week!

https://twitter.com/RajlabN/status/1608877190632071168

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#Global #VariantSoup 12/31/2022

Top lineages with at least 5 key convergent #Spike mutations (#30DayTrends):

BQ.1.1 (24.45%)
BQ.1 (9.38%)
BQ.1.22 (4.14%)
XBB.1 (4.09%)
CH.1.1 (2.71%)👀
BQ.1.2 (2.29%)
XBB.1.5 (2.26%)👀
BQ.1.1.4 (2.04%)
BN.1.3 (1.81%)
BQ.1.1.20 (1.65%)

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Predicted Immune Escape and ACE2 binding of top lineages in USA (relative to BA.2)

Bivalent boosters (OG/Omicron.BA.5) will potentially protect the boosted from getting severe disease/hospitalizations.

Please get #boosted ASAP!

public.tableau.com/app/profile/ra…

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#Hospital #Capacity - (by State/Division)

All hospitalizations not just COVID-19

public.tableau.com/app/profile/ra…

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#COVID19 #Hospitalizations in the #UnitedStates

Please get #boosted (especially > 50 yr old and immune compromised) and #MaskUP!

Hospital Tracker (by States, by age group): public.tableau.com/app/profile/ra…

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Status of the latest #COVID19 Wave in #NewYork #BellwetherState

XBB.1.5 is the dominant #SARSCoV2 lineage in NY

Top Lineages (#15DAYTrends):

XBB.1.5 (52.5%)👀🚀
BQ.1.1 (10.7%)
XBB.1 (6.5%)
BQ.1 (5.3%)
BQ.1.1.4 (2.6%)
BQ.1.3 (1.6%)
XBB.2 (1.5%)

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Rise of highly immune evasive XBB* family of lineages especially XBB.1.5 (Key mutation: Spike F486P) in NY is concerning

fortune.com/well/2022/11/0…

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BQ* Hotspots - #USA #15DayTrends

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Recombinant lineage hotspots - #USA #15DayTrends

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Tracking the current #COVID19 wave, variant soup and #Hospitalizations in #California

BQ.1.22 👀, BQ.1 and BQ.1.1 are the top circulating lineage in CA

[low sequence count]

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Tracking the current #COVID19 wave, variant soup and #Hospitalizations 👀 in #Massachusetts

XBB.1.5 is the top circulating lineage in MA

[low sequence count]

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more on #Massachusetts's XBB.1.5 wave

bostonglobe.com/2022/12/28/met…

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Tracking the current #COVID19 wave, variant soup and #Hospitalizations 👀 in #Connecticut

XBB.1.5 is the top circulating lineage in CT

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Tracking the current #COVID19 wave, variant soup and #Hospitalizations in #NewJersey

XBB.1.5 is the top circulating lineage in NJ

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Tracking the current #COVID19 wave, variant soup and #Hospitalizations in #Pennsylvania

XBB.1.5 and BQ.1.1 are the top circulating lineages in PA

[low sequence count]

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Tracking the current #COVID19 wave, variant soup and #Hospitalizations in #Florida

[low sequence count]

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Tracking the current #COVID19 wave, variant soup and #Hospitalizations in #Tennessee

Only 3 sequences with sample collection dates in the last 15 days available from TN

Not sure which variant is responsible for the surge!

[low sequence count]

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