Vitamin D deficiency is a risk factor for dynapenia (poor muscle strength)
1. Dynapenia is an important risk factor for disability and death later in life. A 4-year follow up study looked at association between #VitaminD deficiency and #dynapenia in 3205 people aged 50 or more.
1. Dynapenia is an important risk factor for disability and death later in life. A 4-year follow up study looked at association between #VitaminD deficiency and #dynapenia in 3205 people aged 50 or more.
2. Vitamin D deficiency (< 30 nmol/L or <12 ng/mL) increased the risk of the incidence of dynapenia by 70% after 4 years. The risk was even higher in people aged 70-79 (4-times higher) and those aged 80 or more (8 times higher)
#MedTwitter
link.springer.com/article/10.100…
#MedTwitter
link.springer.com/article/10.100…
3. Vitamin D participates in both biochemical processes for the maintenance of muscle mass & muscle contraction kinetics. Through its genomic effects, vitamin D exerts an influence on the expression of contractile proteins & differentiation of muscle fibers, which affects the +
4. quantity of muscle mass. Through its non-genomic effects, it participates in the regulation & transport of calcium, which exerts an influence on muscle contraction kinetics. Therefore, through 2 distinct mechanisms, vitamin D plays a role in the generation of muscular strength
5. Take home message
*Good muscle strength in older people is associated with lesser risk of serious diseases and greater longevity.
*Vitamin D should be checked and supplementation started if there is vitamin D deficiency (<12 ng/mL).
*Good muscle strength in older people is associated with lesser risk of serious diseases and greater longevity.
*Vitamin D should be checked and supplementation started if there is vitamin D deficiency (<12 ng/mL).
• • •
Missing some Tweet in this thread? You can try to
force a refresh
