Our final paper from ST-K's series on heart disease is the Strong Heart Study published in 2006 by Xu. This was a study of 3k people in Arizona, Oklahoma and the Dakotas. Conducted through the IHS, it used 24 hour dietary recall.
The patients were followed for about a decade, those with angina or known MI in the past were excluded. In patients under 60, there was a strong association between SFA and heart disease, that disappeared in those over 60. Trans fats had no association in all groups.
The risk ratios for those under 60 were quite significant, with SFA leading to a 5-fold higher rate of coronary death in the highest vs. lowest quartile in that age group. Curiously, MUFA led to a 3-fold increase in risk ratio. ncbi.nlm.nih.gov/pubmed/17023718 
As we have reviewed these studies, there have been several where TFA was not associated with CHD to a statistically significant level. One wonders if using S-T & K's method we could produce a meta-analysis exonerating them. Hard to say.
If we plug the raw numbers from all age groups into a meta-analysis, this study will look like there is no significant relationship between SFA and death from CHD, but let's examine what percentage of heart disease patients are under 60.
The average age at first heart attack in the US is 63 for men. So those patients were excluded at a high rate in the over 60 group, but not in the under 60 group. This alone would cause one to focus more on the under 60 group. ncbi.nlm.nih.gov/books/NBK45688/
This is the final study looking at CHD in S-T & K's paper. Even a cursory evaluation of these papers would cause you to think there was definitely a connection between SFA and heart disease. But S-T & K decided to complicate things by adding stroke, we'll get to that next.
