RESPONSE TO DR. TU 11/16/19:
Thank you for your reply. Apparently, you posit that endometrial tissue &/or vascular masses impinge nerves within region of anterior sacrum to arouse pain. That is an interesting hypothesis, but not without faults...
Thank you for your reply. Apparently, you posit that endometrial tissue &/or vascular masses impinge nerves within region of anterior sacrum to arouse pain. That is an interesting hypothesis, but not without faults...
What is the mechanism of pain arousal? Idea that tissue-derived (endometrium) neurotactic inflammatory species arouse neural pain transducers is novel, but without model in the Endometriosis arena of pathology.
Idea that endometrial implants &/or vascular protrusions bio-mechanically impinge pre-sacral nerves seems improbable.
A theory of this sort reminds me of the long-held regard that Thoracic Outlet Syndrome was due to Scalene muscle impingement of neural tracts exiting cervical spine.
The idea that one soft tissue, muscle, impinged another, nerves, was a failed theory. We now know that impingement occurs between clavicle & first rib, two durable osseous structures.
Even massive cysts and cancer masses are not known for bio-mechanical impingement of contiguous soft tissues & to thereby arouse pain. Cancer tissues arouse pain by infiltration & destruction of other tissues.
To my mind, a better explanation for arousal of musculoskeletal pain & autonomic neural dysfunction (dysautonomia) is direct impingement of neural tracts by hard tissues (bone & ligaments, i.e., disks).
Laseques Sign is a model for this dynamic: dorsal flexion of the foot tugs on long neural tracts to grind them at sites of disk protrusion; at sites where the nerve tracts are fixed at the vertebral foramen.
This phenomenon should be observable by MRI images before & during dorsal foot flexion.
My regard is that subluxation of sacroiliac joints similarly tugs at sacral nerves; impinging them where they are fixed at sacral foramen. It’s soft tissue vs. bone within this pain arena.
Intermittent impingements at these sites include parasympathetic tracts that traverse the pre-sacral plexus contiguous to the ventral sacroiliac joint sulcus.
It is these autonomic neural tract impingements that arouse organ dysfunctions of intestine & bladder (IBS & IC).
Bio-mechanical neural impingements are likely candidates to arouse pain via apathic nerves transferring neural pain signals to the brain; as motor & autonomic nerves are impinged or otherwise being injured.
REFERENCES?: Series of clinical papers, with both data & theory, I published every three years, absent 2010, since 2007; at series of Interdisciplinary World Congresses on Low Back & Pelvic Pain; hosted by Dr. Andre Vlemming, world-class sacroiliac joint expert.
It is at these conferences that one encounters world-class clinical & surgical minds interested in sacroiliac joint dysfunction. At the 2013 Congress in Dubai, I presented two cases of women who experienced remission of Interstitial Cystitis (IC) after sacroiliac joint fusion.
Unfortunately, although I have made a yeoman’s effort to study the sacroiliac joint & to publish my clinical data, others have not taken up leads I have provided; so that there is precious little confirmation of my findings & hypotheses.
I suggest that if you want to study the elusive so-called endometriosis phenomenon & pelvic pain, you should keep your clinical antenna out for women with hypermobile tissues.
These women are commonly found within clinical categories currently denoted by Hypermobility Spectrum Disorder (HSD) & hypermobile Ehlers-Danlos Syndrome (hEDS). They have pelvic pain in spades.
Interestingly, you are the first professional & clinician who has ever given regard or suggestion of interest in my theories & clinical findings. I have often thought that my explanations of natural clinical phenomenon are too simplistic to be believable.
@jennywren_10, would you be so kind as to help me transform this into a thread reader & then DM me & explain how you turn these essays into thread readers?
