Here’s a #tweetorial to explain our #LesionSegregation findings...
biorxiv.org/content/10.110…
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- Mutagens generate lesions on each DNA strand and segregate during replication.
- Daughter cells have non-overlapping lesions, which are then resolved into full mutations.
- Lineages with drivers undergo clonal expansion.
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🇬🇧🇪🇸🇮🇳🇩🇪🇪🇪🇬🇷🇳🇱🇮🇪🇱🇻🇺🇸
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