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Dr Harsh Vardhan Profile picture
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3 Jan, 6 tweets, 5 min read
Disgraceful for anyone to politicise such a critical issue.

Sh @ShashiTharoor, Sh @yadavakhilesh & Sh @Jairam_Ramesh don't try to discredit well laid out science-backed protocols followed for approving #COVID19vaccines

Wake up & realise you are only discrediting yourselves !
Vaccines approved globally based on gene encoding spike proteins have protective efficacy of over 90%
However, COVAXIN based on whole inactivated virus has other antigenic epitopes in addition to spike protein
So,it’s likely to have similar protective efficacy reported for others
COVAXIN is more likely to work against newer variants like N501Y Variant (UK variant) & any other that may arise due to antigenic drift as it contains immunogens (epitopes) from other genes in addition to those from Spike protein
Inactivated virus from NIV also had D614G mutation
The data from COVAXIN Phase I & II clinical trials reveals that it not only produces neutralizing antibodies in all participants but also sensitises  CD4 T lymphocytes that imparts durable immune response

@BharatBiotech @PMOIndia @ICMRDELHI @icmr_niv @MoHFW_INDIA @DBTIndia
Our experience with inactivated vaccines not having serious adverse events was also observed in Phase II done among 380 study participants in BBV152 trial in 21280 Person days follow up.
No serious adverse events seen. Only 7% persons receiving 6 microgram dose had mild symptoms.
There were no seroconversions in those who were provided vaccines in Phase II as well as Phase I of COVAXIN clinical trials.
@ICMRDELHI @MoHFW_INDIA @icmr_niv @DBTIndia @BharatBiotech

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More from @drharshvardhan

Dr Harsh Vardhan Profile picture
25 Nov 20
#LucknowUniversity परिवार को 100 वर्ष पूरा होने पर हार्दिक बधाई। सौ वर्ष के इस सफ़र में अनेक उपलब्धियों का एक जीता जागता इतिहास जुड़ा है।

विश्वविद्यालय के #CentennialFoundationDay पर आज PM श्री @narendramodi जी की उपस्थिति और उनका आशीर्वाद काफ़ी मायने रखता है।

@myogiadityanath
University सिर्फ़ उच्च शिक्षा का ही केंद्र नहीं होती, ये ऊंचे संकल्पों, ऊंचे लक्ष्यों को साधने की एक बहुत बड़ी ऊर्जा भूमि होती है।

#LucknowUniversity के #CentennialFoundationDay पर PM श्री @narendramodi जी के एक-एक शब्द छात्रों और शिक्षकों के भीतर की ताक़त को जगाते प्रतीत हुए।
PM श्री @narendramodi जी का छात्रों को शानदार संदेश -

छात्र जीवन को Enjoy भी कीजिए, Encourage भी कीजिए।

#LucknowUniversity #CentennialFoundationDay @PMOIndia
Read 4 tweets
Dr Harsh Vardhan Profile picture
24 Nov 20
The world has become increasingly reliant on STI for its progress.

Exhorted the astute scientists at the 1st SCO Young Scientist Conclave to 'Innovate, Patent, Produce & Prosper' to lead our countries towards faster development.

@IndiaDST @csiriict @MEAIndia
Initiatives like MANAK, ATAL Tinkering Labs are inculcating scientific temper among our youth.

We are providing young scientists with opportunities & exposure to challenging leadership roles at our specialised research labs for AI, smart materials & other new technologies.
India is marching on with the mantra of "Innovation for the people & by the people"

Various policy measures & an enabling STI ecosystem has helped India improve its ranking to 48 on the Global Innovation index.

We are now 3rd in terms of number of publications filed.

@IndiaDST
Read 4 tweets
Dr Harsh Vardhan Profile picture
24 Nov 20
माननीय PM श्री @narendramodi जी, #कोरोना के खिलाफ़ लड़ाई में सभी राज्यों व संघ शासित प्रदेशों को साथ लेकर चलने की आपकी पहल के लिए हृदय से आभार। अदम्य साहस और अटूट समर्पण के साथ तूफ़ान से लड़ना और संकट की घड़ी में सबको साथ लेकर चलना यही तो आपकी पहचान रही है।

@PMOIndia #COVID19 ImageImageImageImage
PM श्री @narendramodi जी ने #कोरोना की स्थिति पर सभी राज्पों के CMs व संघ शासित प्रदेशों के साथ संवाद कर संकट की घड़ी में विश्वास का भाव भरने की कोशिश की है।

उनकी चिंता देश के लोगों को जल्द #vaccine उपलब्ध कराने की है, लेकिन उन्हें लोगों की Safety की भी चिंता है।
@PMOIndia
#CovidVaccine प्राथमिकता के आधार पर किसे लगाई जाएगी, ये राज्यों के साथ मिलकर तय किया जाएगा।

PM श्री @narendramodi जी की नीति हर राज्य के सुझाव को महत्व देना है, क्योंकि आख़िरकार उनको अंदाज़ा है कि उनके राज्यों में कैसे काम होगा।

@PMOIndia
Read 5 tweets
Dr Harsh Vardhan Profile picture
29 Aug 20
It was noted that despite being resource constrained and densely populated, timely #lockdown & rapid augmentation of infrastructure by India have helped to keep the case/ million & deaths/million considerably lower as compared to other countries

@PMOIndia @MoHFW_INDIA
Within the country, eight States (#Maharashtra, #Karnataka, #AndhraPradesh, #TamilNadu, #UttarPradesh, #WestBengal, #Odisha and #Telangana) contribute to around 73% of the active caseload, as of today

@PMOIndia @MoHFW_INDIA #GoM
Moreover, seven States (#Maharashtra, #Delhi, #TamilNadu, #AndhraPradesh, #Karnataka, #UttarPradesh and #WestBengal) account for 81% of total deaths.

@PMOIndia @MoHFW_INDIA #GoM #COVID19 #IndiaFightsCorona
Read 4 tweets
Dr Harsh Vardhan Profile picture
16 Jul 20
ZyCoV-D, the plasmid DNA vaccine designed & developed by @ZydusUniverse & partially funded by @DBTIndia has initiated Phase I/ II clinical trials in healthy subjects, making it the first indigenously developed vaccine for #COVID19 to be administered in humans in India.@IndiaDST
The adaptive Phase I/ II dose-escalation, multi-centric study will assess the safety & immunogenicity of the #vaccine. The human dosing of the vaccine marks a key milestone since the launching of the accelerated vaccine development programme for #COVID19 in Feb 2020. @DBTIndia
This is an important milestone for #AtmaNirbharBharat. I hope that the vaccine continues to show positive outcomes as it has done so far in the pre-clinical phase where it was found to be safe, immunogenic and well-tolerated.

@DBTIndia @IndiaDST @ICMRDELHI
Read 4 tweets
Dr Harsh Vardhan Profile picture
27 Jun 20
आज #GoM की बैठक में #COVID19 से लड़ने की तैयारियों और आगे की रणनीतियों के बारे में विस्तार से चर्चा हुई। @ICMRDELHI के DG @ProfBhargava जी ने #testing Labs के बारे में जानकारी दी।

@DDNewsHindi
@PMOIndia @MoHFW_INDIA
Only 8 States (Maharashtra, Tamil Nadu, Delhi,Telangana, Gujarat,UP, Andhra & WBengal) are contributing 85.5% of active caseload & 87% of total deaths

15 Central Teams consisting of public health experts/epidemiologists/clinicians & a JS deployed to provide tech support
#GoM
A Central Team is currently visiting Gujarat,Maharashtra & Telangana to strengthen ongoing efforts wrt #Covid_19

#GoM also briefed on role of #ITIHAS & #AarogyaSetu in contact tracing & prediction of potential hotspot areas
Both are being extensively used in containment strategy
Read 6 tweets

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