Would you like to know about a randomized crossover trial that used a modified #ketogenic diet in #Alzheimers disease? 1/9
26 patients with clinically confirmed #Alzheimers disease were randomly assigned to a modified ketogenic diet or a usual diet supplemented with low-fat “healthy” eating guidelines and enrolled them 2/9
in a single-phase, assessor-blinded, two-period crossover trial. That means (2) 12-week treatment periods, separated by a 10-week washout period. 3/9
Primary outcomes were mean within-individual changes in assessments over 12 weeks. The assessments included a standardized cognitive exam and assessments of daily functioning and quality of life. 4/9
Secondary outcomes measured changes in cardiovascular factors and any adverse effects of the diet. 5/9
Improvement in cognitive function was not statistically significant but was definitely there. Improvements in functioning and quality of life were statistically significant. This is a breakthrough study. 6/9
Because they found that compared with the usual diet supplemented with low-fat healthy eating guidelines, patients on the ketogenic diet improved in daily function and quality of life. 7/9https://link.springer.com/article/10.1186/s13195-021-00783-x
If this #RCT had been a drug study, it would have been all over the news as a revolutionary treatment. But because there is no profit motive in #ketogenic diets, I bet nobody told you. 8/9
There are zero medications that do this for people suffering from #Alzheimers disease. Please retweet the first in the Tweet thread so someone suffering or their family members watching them suffer knows this is a way they can feel better. 9/9
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