Hot take about this meme. It works so well comedically, because we read it from right to left. In cinematography for sitcoms. Regular plot devices enter from left e.g Rachels apartment. Crazy plot devices enter from right e.g Chandlers apartment 
This is the XY axis in cinematography. Easily digestible, or likeable, normal, "good guys" enter from left X axis.Because in the west we read easily from left to right. Eccentric, conflict driven information or "bad guys"enter right to left, so we give the Y axis extra attention
To test this out.Try watching something like Fawlty towers flipped horizontally. It feels weird,& doesn't work as well.Basils desk is on the left, he maintains control here.Crazy problems enter from the restaurant on the right and create conflict.Flip it, and it's uncomfortable.
I should have done a fucking podcast on this and not wasted it on a tweet. Also, forget the Y axis above. That's for vertical information. It's the left and right of x axis that this meme operates on.
Comedy at its most basic is conflict. Think of Seinfeld too. Jerrys Couch where basic setup information is presented, happens comfortably on the left. Then Boom, in comes George or Kramer from the right, with a conflict that creates the jokes.
Also, I could go full blown cultural marxist on this and argue that the world map, as presented to us, and created by Western colonial powers feeds into a visual narrative of good things coming from the left of x axis (west), and bad,weird things coming from the right (east)
