Thread by @cispt2

This article on a 'miracle cure' for cancer has me so angry. How can unpublished, non-peer reviewed tripe get any attention at all? Some of the issues are in the thread below:
jpost.com/HEALTH-SCIENCE…

First, the experimental theraputic modality is based on phage-display-derived peptides against various targets that are apparently coupled together with a 'peptide toxin'. Presumably the peptide toxin is Monomethyl auristatin E

Next, the article states they have "concluded its first exploratory mice experiment, which inhibited human cancer cell growth and had no effect at all on healthy mice cells".

THIS MAKES SENSE! Human-target-specific peptide will recognize human epitopes no the tumor xenograft cells, but possibly not the mouse epitopes. That's why ADCs and CAR-T cells look awesome in mouse models - highly specific binders to implanted human cells w low mouse off-targets

And then the kicker piece of BS hype: "Aridor added: “Our results are consistent and repeatable.”
THEY JUST SAID THEY FINISHED THE FIRST EXPERIMENT!

The website for aebi-bio.com itself is truly a sight to behold. A mix of hype, quotes, with no pipeline shown. Possibly my fave:

Or maybe the series of cracking inspirational quotes

At any rate, this is a classic perfect storm of an arbitrary article or media release being picked up by the media for absolutely no reason I can see, leading to this:

https://twitter.com/7NewsMelbourne/status/1090419140622376961

@Dereklowe see thread above. @whereisdaz

And @Dr_Ginni - whoever you are - give yourself an uppercut.

You say MuTaTo, I say MuTaTo

(Multi-Target Toxin)