Yes! The differential dx for this is anything that may block blood flow, mainly vasculitis and vasculopathy. So, how exactly do you make the dx?
✔️Calciphylaxis is from impaired blood flow in skin arterioles +/- thrombosis
✔️It's crazy painful & terrible for patients
✔️Evaluation includes RFs (mainly ESRD on HD), skin bx, labs, & ruling out other causes
✔️Mortality is high, largely from sepsis