Thread by @AllenInstitute

In a new study out in @nature, our researchers make a big step forward in our quest to map the brain. Study findings lay the groundwork to better understand brain disorders & diseases such as #Alzheimers and #schizophrenia.

alleninstitute.org/what-we-do/bra…

This new study describes a high-resolution expansion of our #openscience Allen Mouse Brain Connectivity Atlas-- the most detailed map of connections in a mammalian brain to date. Access via: connectivity.brain-map.org

Using a computational approach, our researchers found that different sections of the cortex and thalamus can be mapped into a hierarchy, much like a company’s org chart – although not all connections followed this hierarchical structure. #brainmapping

Inspired by these findings, our researchers are now exploring a similar map of connections in a mouse model of #Alzheimers to investigate how the wiring diagram — and its underlying organization — might change in this prevalent form of #dementia.

@harrisjuliea Read our latest study out in @nature.
"Hierarchical organization of cortical and thalamic connectivity"
nature.com/articles/s4158…