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People have talked about 3D printing as a buffer against supply chain shocks since forever. It certainly won't do everything, but it might be an option for mechanical parts if your Chinese vendor has shut down.
stratasysdirect.com/resources/info…
Separately but relatedly, all the blockchain supply chain transparency work will finally have its moment.

This crisis gives an object lesson to everyone on the financial importance of knowing your supplier, and your supplier's supplier, and so on.
www2.deloitte.com/us/en/pages/op…
Alternatively, here's @ricfulop on why 3D printers may not be that helpful even in supply chain shock, not even for spare parts (assuming printer still around). Not my area at all, but v interesting.
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More from @balajis see all

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Balaji S. Srinivasan
@balajis
👍

Btw, one reason this approval went fast is because Roche has good reputation given body of work.

This suggests an alternate regulatory paradigm: clear the company, not every drug/device.

Similar to how CLIA works, where a lab is cleared and then can roll out new tests.
That clearance would need to be maintained, but it works for labs.

Normally, a CLIA lab director can roll out a new laboratory developed test without submitting it for “pre-market review”.

In this emergency, FDA CDRH gained ability to bottleneck this normally fast process.
One secret of regulatory review is that it’s not fully based on rule-of-law or even science.

A huge part of it is the *reputation* of applicant in regulator’s eyes, as well as regulator’s rep with public.

This book is “pro FDA” but discusses this thesis.
press.princeton.edu/books/paperbac…
Read 3 tweets
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Balaji S. Srinivasan
@balajis
This is where I disagree with Matt.

The federal government has failed. CDC can’t run tests at scale. FDA doesn’t understand what an emergency is.

Biopharma can manufacture drugs and vaccines, Labcorp/Quest can run tests, Google can certainly build websites.

Let them get at it.
The ideal would be a competent federal government like Singapore, Israel, Estonia, Taiwan.

We don’t have that. We aren’t going to get that. In a life or death situation we need to be real.

The requisite technical expertise is simply not present in the US federal government.
State and local governments do have a role to play. @GovInslee of WA should have said “week” rather than “day” in the clip below, and he’s off by one in the math, but directionally he shows a greater understanding of the problem than the feds.
Read 7 tweets
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Balaji S. Srinivasan
@balajis
The virus crisis is now also a financial crisis.

The dynamics described in the post below are now underway. As is the printing.

Just like people were forced to switch to remote everything before it was ready, there’s a chance crypto may have to step up next. It’s not yet ready.
I’d encourage everyone in crypto to look past price fluctuations.

Plan for the *possible* scenario where the (understandable) efforts to stabilize the economy destabilize it in certain ways, such that folks need crypto.

Not the way we wanted to build this but need to be ready.
Here are a few scenarios:

1) Flight to dollars increases demand for stablecoins like DAI, USDC

2) Too much dollar printing causes a flight to BTC (obvious)

3) Shortages cause people to resort to marketplaces like @openbazaar

4) Censorship may necessitate IPFS and the like
Read 3 tweets

Related threads

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Per Axbom
@axbom
1) In Digital Compassion I outline seven ways in which people experience negative impact from tech and digital services. Number six is what I call ”neglect of ecosystem”.
2) "Neclect of ecosystem" is harm based on the failure of an organisation to assume responsibility for people occupying the extended ecosystem necessary for the development and use of its services and products.
3) For example, many thousands of miners in the Democratic Republic of Congo work each day to excavate cobalt by hand, for the benefit of lithium-reliant companies such as Apple, Alphabet (Google), Microsoft and Tesla. Roughly 60% of the world's cobalt originates in DR Congo.
Read 30 tweets
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IndoPacific_SCS_Info
@IndoPac_Info
#China backtracked on nearly all aspects of #US trade deal - All of us that follow & know China knew that this was never going to fly. You can't negotiate with a rogue, predatory state like China. This is for the better. mobile.reuters.com/article/amp/id…
The diplomatic cable from Beijing arrived in Washington late on Friday night, with systematic edits to a nearly 150-page draft trade agreement that would blow up months of negotiations. The document was riddled with reversals by China that undermined core US demands, sources said
In each of the 7 chapters of the draft trade deal, China deleted its commitments to change laws to resolve core complaints that caused the US to launch a trade war: theft of US IP & trade secrets; forced tech transfers; competition policy; access to financial services, etc, etc.
Read 43 tweets
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Richard James
@RichJamesBits
I have reached a whole new level of #PISSEDOFF.

I didnt think such a #dark and #scary state, or level, could be reached. It may top 12-14-17's causation. It's. That. Bad. So, I've prepared a statement...

docs.google.com/document/d/1_J…

#PascoSheriff #HaveYouAllNoShame @CigarCityBeer
Dear @FBI,
I must implore you ask your colleauges in @FBITampa to help research this new level of #PISSEDOFFNESS. As locals, they may offer a special indepth knowledge of this new level I have reached. This is not fair & law enforcement must #investigate. No one deserves this.
This is my #apogee of #Pissedoffness.
If #motherfuckers & #tears werent a noticable level.
If #HUSH or #INTIMIDATION tactics being deployed didnt strike a chord.
If #EVIDENCE, PROOF, or 30k Bonds didnt #WOW YOU.
If posting mom with no shred of investigatable value wasnt enough...
Read 463 tweets
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SCM Consultant
@oarhtanirs
Make in India (MII)
A pre commercial run of Vande Bharat Express stopped for a brief while for some technical snag n all wizards in Ind started giving gyaan on how MII has failed n what must b done 2 fix it.
well, wht exactly is MII?
Let me try to explain it here..

1/n
MII is not a short term project but long term deep thought on looking to make things in india instead of importing it from outside or making it on foreign soil for our export market..

Its like a challenge thrown by PM to our manufacturers..

2/n
Let's look at simplest of things like a serial set of lights that we use for various functions n events
There r many attractive models of these available in the market that serve the purpose well..

3/n
Read 35 tweets
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Esfandyar Batmanghelidj
@yarbatman
1. The conventional wisdom has been that #China's strategic trade + energy interests would see it defy US secondary sanctions on #Iran. Our new @BourseBazaar report, drawing on recent China-Iran trade data, suggests that the conventional wisdom is wrong.
bourseandbazaar.com/research-1/201…
2. The years when #Iran was under multilateral sanctions were boom years for China-Iran trade. China openly flouted US sanctions by purchasing historic volumes of Iranian oil while exporting a wide range of goods, winning marketshare as European traders pulled back.
3. At the heart of this trade was Bank of Kunlun, a subsidiary of state oil giant CNPC. Kunlun was the "bad bank" designated by the Chinese government to facilitate payments for trade with Iran. The bank thrived as it carried billions of dollars of trade on its ledgers.
Read 20 tweets
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Joseph Stalin
@StalinIsBack
1/8 My favorite #quote by #JosephStalin, which explains the scientific, #DialecticalMaterialist explanation of true freedom in material reality, not just as an abstract ideal. #StalinIsBack #StalinLives #JVStalin #Stalin #StalinQuote #StalinQuotes #Truth #MELS #MarxismLeninism
2/8 Having an #objective, #rational, #ScientificSocialist, #Dialectical, & #Materialist viewpoint allows us to accurately see & evaluate & analyze #Truth & #Reality as they truly materially exist in this universe.
3/8 An idealistic, dogmatic viewpoint, which capitalists have, however, makes one irrational enough to 'see' freedom where freedom stays trapped on a piece of paper while people are oppressed in their actual lived lives.
Read 586 tweets

Trending hashtags

#NightmareOfFascists #tomorrow #Syrian #deBlasio #Chinese #Victory #against #MELS #PowerToThePeople #alone #judicial #mainstream #CPIML #NoWarOnIran #Engels #OperationPaperclip #RedArmy #GDR #Gori #SoHelpMeGod #TrudeauResign #PrimaryElection #EveningTroll #Libyan #CCP

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