"#Thermodynamics of Far-From-Equilibrium Systems, #Biochemistry, and #Life in a Warming World"

Today's SFI Virtual Seminar by Mark Ritchie of @SyracuseU

Streaming now – follow this thread for highlights.

facebook.com/santafeinstitu…

#Biology #Ecology #GlobalWarming
"If we look at the temperatures at which most biological #enzymes fall apart, it's upward of 50º — but most enzymatic activity fails well below that. What's causing this decline? The Standard Model doesn't account for this."

Mark Ritchie of @SyracuseU:
facebook.com/santafeinstitu… ImageImageImage
Here's why #GlobalWarming is not just going to be "great for plants":

Thermodynamic constraints on living systems mean rising temperatures affect diffusion and transport of molecules across membranes, and too much heat messes with #photosynthesis.

Mark Ritchie of @SyracuseU: ImageImage
Some like it hot — but everyone has a "too hot," considering the thermodynamics of molecular transport and diffusion in living systems.

Even as rates of catalysis keep going up, entropy production eventually declines. Models by Mark Ritchie of @SyracuseU, speaking at SFI now: ImageImageImage
Element concentration is temperature-dependent, and availability of key ingredients like N & P matter to the optimal rates of biochemical reactions — suggesting new estimates for #climate-dependent #biodiversity.

Mark Ritchie of @SyracuseU offers a counterintuitive hypothesis: ImageImageImageImage
"A lot of people have noticed that as things have gotten warmer, the nutritional content of vegetables has declined (controlling for all other variables)."

Mark Ritchie (@SyracuseU) on how to make more nuanced models of biological temperature-dependence:
facebook.com/santafeinstitu… Image

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More from @sfiscience

7 Dec 20
This week at SFI: "#Complexity and the Structure of #Music: Universal Features and Evolutionary Perspectives Across Cultures", an #interdisciplinary working group assembled to explore new frameworks for understanding music. Stay tuned for highlights!

santafe.edu/events/complex…
"Every pitch class set is connected to every other pitch class set."

– @mbnUNT, co-organizer of this week's #musicology working group, presents on how to understand the #topology of #harmonic structures in music with #network diagrams (e.g. Pic 4 with #JSBach's BWV 66):
Once you represent a musical composition as a network, it is possible to examine the evolutionary dynamics of its harmonic content over time, as explained by @mbnUNT in his opening talk for this week's SFI #musicology working group.

(Ironically, this #Beethoven is #scalefree:)
Read 21 tweets
25 Nov 20
Today's talk is with neuroscientist #KarlFriston of @ucl, who will offer a heuristic proof suggesting that life is an inevitable emergent property of any weakly mixing random dynamical system that possesses a #Markov blanket.

Tune in here at 12:15 PM MT:
santafe.edu/events/me-and-…
...and because it's 2020 and nothing is ever simple, we are having technical issues with the stream. The talk is recorded and we will upload it across all of our platforms ASAP. Our apologies!
Spatial boundaries are statistical boundaries: #KarlFriston on #MarkovBlankets, the reciprocal interfacing between internal and external states.

Follow this thread for more highlights from the talk and stay tuned for the video link...
Read 11 tweets
21 Aug 20
@aeonmag @C4COMPUTATION @MelMitchell1 "Simple cause-effect reasoning, to which the human mind can default, is not a good policy tool. Instead of attempting to narrowly forecast and control outcomes, we need to design systems that are robust and adaptable enough to weather a wide range of possible futures."
@aeonmag @C4COMPUTATION @MelMitchell1 "All human societies are collective & coupled. Collective, meaning our combined behaviour gives rise to society-wide effects. Coupled, in that our perceptions & behaviour depend on the perceptions & behaviour of others & on the social & economic structures we collectively build."
Read 11 tweets
18 Aug 20
Streaming now: @michaelmina_lab of @HarvardBiz gives today's SFI Seminar on "#Testing our way out of #COVID19: A bumpy but possible path forward."

facebook.com/santafeinstitu…

Feat. work with Former SFI Postdoc @DanLarremore.

Follow this thread for highlights...
Now may be the best window to squash #COVID19 before flu season begins, but pandemic surveillance—especially in the US—has been a mess.

What are the relative strengths of virus testing vs. serological testing?

@michaelmina_lab speaking at SFI right now:
facebook.com/santafeinstitu… ImageImageImage
"Really baseline testing doesn't give you enough information. If it tells you there is 5% infection in a nursing home it doesn't tell you if the virus is increasing. But serological testing can. These are complementary tools."

@michaelmina_lab at SFI now:
facebook.com/santafeinstitu… Image
Read 10 tweets
27 May 20
Mimicking Simple Life Without Biochemistry

Follow this thread for insights from today's SFI Seminar by Juan Pérez-Mercader (SFI + @Harvard), which you can watch live on our FB page. Recording will be saved for later viewing at this link, as well as YT:

facebook.com/santafeinstitu…
More info about today's seminar by SFI External Professor Juan Pérez-Mercader (@Harvard) on Mimicking Simple Life Without Biochemistry:

santafe.edu/events/mimicki…

#astrobiology #biochemistry #complexity
What properties characterize life? The search for a fundamental theory of #biology continues to face some serious challenges:
• n = 1
• no unified math
• can't modify carbon experimentally
• biology is still process-description
BUT: ✨ info-metabolism-replication-evolution ✨
Read 10 tweets
29 Apr 20
Today at SFI:

External Professor @DaniSBassett (@Penn) on addressing #inequity in the scientific community caused by #bias in #citation practices—focusing on the evidence of a growing #gender imbalance in the reference lists of #neuroscience research.

santafe.edu/events/citing-…
The proportion of #neuroscience papers with woman first or last authors grew from 1995 to 2018, but the undercitation of female authors actually *increased* in that time.

SFI's @DaniSBassett (@Penn) on #gender #inequity in the scientific community:
Undercitation of #neuroscience research with first or last woman authors appears to be driven predominantly by the reference lists of papers written by male-male teams.

This is not to say, however, that all men undercite women, or that women do not also undercite women:
Read 7 tweets

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