Thread by @andreaprinzi

1/ I loved writing this new @ASMicrobiology article. I talked to Dr. Derick Kimathi (@Toinoti, medical researcher in Kenya), about using fractional doses of yellow fever #vaccine. I hope you find this as interesting as I did #IDtwitter #epitwitter
asm.org/Articles/2021/…

2 / This is a follow up article to the one I wrote back in May that briefly detailed the history of #YellowFever in the United States, and how the development of #diagnostics for the disease as well as modern research stemmed from that #history.
asm.org/Articles/2021/…

3/ The #YellowFever #outbreak that started in Angola in 2015 ravaged major cities like Luanda & Kinshasa, and resulted in 11 imported cases in China - a country that harbors the mosquito that spreads the yellow fever virus and has a population immunologically naïve to YF.

4 / This particular #YellowFever #outbreak exhausted the global supply of #vaccine and sparked initiatives by @WHO @gavi @UNICEF that evaluate how to best ensure that everyone who needs a life-saving vaccine gets one.

5 / @Toinoti and fellow researchers at @KEMRI_Wellcome have been leading clinical trials that assess the safety and efficacy of the use of fractional doses for #YellowFever #vaccine. This important #research is laying the groundwork that supports the future use of this method.

6 / I was so honored to speak with @Toinoti about the amazing work being done in Kenya, and I learned so much from writing this article. Give it a read to learn more about why we should all care about preventing #YellowFever, how fractional dosing performs, and what's next.

7/ asm.org/Articles/2021/…

#CoSPHIDEpi2021 #IDTwitter #EpiTwitter #PublicHealth #Vaccines #globalhealth

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