Thoughts on upcoming #COVID19#serology tests:
This is actually quite a challenge! (#Diagnostics often involve a lot of complexities). There is a lot of pressure to roll these tests out, but they need to perform well, or we do more harm than good. #MicroRounds (A thread)
WHY we need these soon: 1. Contact tracing. 2. Can be used to test if a vaccine is working during a clinical trial (70 of them ongoing right now, I believe) 3. Inform public policy makers about rate of asymptomatic cases + previous infections/exposures =informed decision making
How is developing a #PCR different than developing a #serology test? 1. #PCR tests detect viral RNA/DNA (in this case RNA) and can be pretty straight-forward in terms of development 2. #Serology relies on knowing about the #SARSCoV2 structure and how the human body responds.