Thread by @vipintukur

What happens if we allow #SARS2 to become endemic? What’s going to happen to us & what’s going to happen to the virus?

If we allow it to become endemic—and some would argue that it is already endemic—this does not mean that it is going to attenuate, not whatsoever. 1/

It is not true that more transmissible versions of #SARS2 will be more benign. What we are seeing is more aggressive, more transmissible versions which are creating more severe illness. And the virus is still adapting to our physiology. It’s doing it at a fantastic rate 2/

What we’re going to see is that it will continue to work against our immune systems, meaning become more immune evasive. It’s going to become more chronic as an infection. 3/

For this virus to become #endemic, we would see a lot of *maimed* people with #autoimmunity. And with immune memory, that is not able to fully prevent mild and moderate infections again. 4/

The damage could be cumulative. The virus can also cause vascular injury like what we see with Feline CoV in a disease called feline infectious peritonitis, which is fatal for cats where it causes very small capillaries to become what’s called “string vessels” and get blocked 5/

Additionally, it can potentially “kill off” parts of the vascular system, especially in the brain.
For this thing to become endemic also means these disease-causing mechanisms are not going away. 6/

In summary, the virus is causing severe immune dysregulation, meaning the ability for B-cells & T-cells to communicate and provide an appropriate response is being severely impacted. 7/

And, additionally, the #dysregulation is causing T-cells that don’t routinely attack your own body to now create the potential for an #autoimmune disorder to develop in people who have been infected by this virus. 8/

There was a recent study that found it was 20,000 years ago that an ancient #coronavirus etched its imprint into our DNA. It selected traits in us that we’re better at surviving the infection. So, it selected us & exerted a selection pressure on us 9/

sciencedirect.com/science/articl…

The study found evidence that a previously unknown ancient CoV infected people in east Asia: China, Japan & Vietnam.

The discovery that a CoV outbreak lasted for approximately 20,000 years has very important implications for the current pandemic. 10/

wsws.org/en/articles/20…

What is going on right now might be going on for generations and generations. 11/

Modern science has enabled humanity to understand viruses & intervene to predict & control any pandemic, but this scientific knowledge has been ignored by the political elite as they impose a herd immunity program that has allowed the virus to proliferate almost unhindered. 12/

Summary: What happens with endemic #Covid:
1-SARS2 will not become benign
2-We may see a lot of maimed people w/ autoimmunity
3-Vascular injury & “string vessels" blocking capillaries
4-Further decreases in life expectancy
5-Herd immunity approach will be disastrous 13/

The above thread is based on a recent interview of T cell immunologist @fitterhappierAJ 👇 14/end

wsws.org/en/articles/20…