There are positive effects of the #ketone body beta hydroxy-butyrate (BHB) on vascular function. Why? Very likely, the following things that we already know BHB does. And quite frankly, there are likely additional mechanisms that haven't even been discovered yet. 🧵(1/10)
BHB lowers high blood sugar, and that reduces the production of reactive oxygen species #ROS and #inflammation mediators. In other words, BHB reduces Oxidative Stress (2/10)
BHB increases endogenous #antioxidant production by upregulating gene expression in those pathways. So yes, #BHB reduces Oxidative Stress from that mechanism as well. (3/10)
BHB may also lower sympathetic activation of endothelial cells and reduce #vascular resistance. (4/10)
Why is all that super good for #brain health? Reducing oxidative stress reduces inflammation in your veins and capillaries. This keeps inflammation down and protects those tiny blood vessels in the brain. (5/10)
Reduced vascular inflammation means you don't burn through your #micronutrients so darn fast, and you maybe get to use more of them to #levelup instead of always dealing with chronic inflammation. I mean, it's nice to have those for other things. Right? (6/10)
Reducing vascular resistance means your brain gets better blood flow. It's important to understand that recurrent and chronic #brainfog and early symptoms of #dementia can often have a vascular component. (7/10)
Once again, I don't make this stuff up. Here is a journal article talking about the vascular benefits of the BHB ketone body. The administration for this study was a BHB Ester. (8/10)…
Now, somebody, please do a study where you put people on ketogenic diets for 5 years and do measures of vascular, heart, and brain health! 🧠 (9/10)
I can only imagine what a nice, steady flow of BHB produced through a longer-term #ketogenic diet would do for the health of these vital tissues! (10/10)

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More from @KetoCounselor

Feb 7
Wondering what research to print out and bring to your doctor when you discuss the use of a ketogenic diet to treat your mental illness? Trying to put together your team to support you in your goal to feel better? Let's do a thread! 🧵 (1/8)
You can also print out the first page abstracts (some articles are really long), and some of you even have ways to send these via email to your docs. Here we go! (2/8)
Sethi, S., & Ford, J. M. (2022). The Role of Ketogenic Metabolic Therapy on the Brain in Serious Mental Illness: A Review. Journal of psychiatry and brain science, 7(5).… (3/8)
Read 8 tweets
Feb 7
All psychiatric medications need to be carefully monitored by a prescriber when their patient is moving to a ketogenic diet as a treatment for mental illness or neurological disorder. (1/6)
Two important psychiatric medications to pay attention to when using a ketogenic diet are anticonvulsants and lithium. Their blood levels can change early on in treatment. (2/6)
You can learn more about medications and ketogenic diets by listening to @GeorgiaEdeMD on this video by @Metabolic_Mind (3/6)

#psychiatricmeds #anticonvulsants #lithium #mentalhealth
Read 6 tweets
Feb 7
Some of you want to consider the ketogenic diet to treat your mental illness or neurological symptoms, but hearing about the potential for the Keto Flu has scared you off! Let's talk about how to avoid it. (1/6)
It's a common experience for those starting a ketogenic diet, especially if you have drastically cut carbs very quickly trying to get into a state of ketosis. Gradually reducing carbohydrates and increasing healthy fats can also help minimize symptoms. (2/6)
Luckily, keto flu symptoms can be treated. First, you need to increase your water intake and be very diligent about your electrolytes. Sodium, potassium, and magnesium. (3/6) #electrolytes
Read 6 tweets
Feb 6
Can a professional in #neurology please explain to me why we don't put people on ketogenic diets post-stroke to help their recovery? (1/4)
In aged-rats they found cognitive function was improved with ketosis under normal and hypoxic conditions and that ketosis induced the development of new blood vessels and increased brain capillary density. (2/4)
This suggests that a ketogenic diet could revitalize the neurovascular unit and improve cognitive functioning after hypoxic injuries. (3/4)
Read 4 tweets
Feb 6
Thread Alert! 🧵Starting the conversation with your doctor about using a #ketogenic diet to treat mental illness can be daunting, but it's important to be proactive about your health. #bipolar #depression #schizophrenia #ocd #anxiety (1/9)
Mention the information you've heard from other doctors and the specific mental health condition you are hoping to treat with the #keto diet. (2/9)
Express your eagerness to try the diet, but also emphasize your concern for safety and your willingness to work closely with your doctor. (3/9)
Read 9 tweets
Feb 5
Some of you who are on a ketogenic diet may not feel very well after your protein shake, especially whey protein. (1/5)
But it's not necessarily because you are having a reaction to dairy. More likely, it's the amino acid profile and amount. (2/5)
Leucine, alanine, cysteine, glycine, arginine, serine, and proline are ketogenic amino acids that can affect serum glucose concentration and insulin sensitivity. (3/5)
Read 5 tweets

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