Discover and read the best of Twitter Threads about #pharmacogenomics

Most recents (3)

Part 5 #Tramadont #tweetorial
(in which #Tramadont remains a hilariously accurate descriptor of tramadol!)
@NarouzeMD @EMARIANOMD @toby_ashken @DavidJuurlink

CYP2D6 & tramadol is not overrated at all.
Here is a picture of the tramadol metabolism pathway (PMID 11454734) (1/7)
We can agree that M1 is the metabolite which provides opioid analgesic effects. (PMID 10961373) (2/7)
M1 is metabolized by CYP3A4 & CYP2B6 (not CYP2D6 as you suggested) to M5. (PMID 24849324) (3/7)
Read 7 tweets
#Tramadol, a game of analgesic roulette, will it work or won’t it? Will your patient obtain analgesic effects or will they have a seizure, respiratory depression, or various other side effects...🤷🏼‍♀️that’s why it’s been nicknamed #Tramadont! Its variable effects are (1/3)
attributable to hepatic enzyme CYP2D6;unless you know your pt’s CYP2D6 genetic polymorphism (which I haven’t come across anyone who does)AND a comprehensive list of all of their home meds, don’t prescribe it!🙅🏼‍♀️
#pharmacyeducationboard #twitterx #medtwitter #pharmacogenomics (2/3)
Thank you to our #pharmacyresident for putting this one up, and to @DavidJuurlink & @ToxAndHound for the inspiration. 🙂💡 (3/3)
Read 4 tweets
I was born & raised in #Medellin Colombia, an amazing & vibrant city in the middle of the mountains.

Please do not mention #Narcos or #Escobar when you hear Medellin!

Medellin is much more than that #eternalspring #innovation #Entrepreneurship #mountains #coffee #greatpeople
I was born & raised in #Medellin Colombia, an amazing & vibrant city in the middle of the mountains.

Please do not mention #Narcos or #Escobar when you hear Medellin!

Medellin is much more than that #eternalspring #innovation #Entrepreneurship #mountains #coffee #greatpeople
Went to a great school in #medellin & at 17 started #medicine not because I wanted to be a clinician but because I liked the #science & my family and #mentors told me #medicine was broader and could open more doors for me #VoicesIWS #Thread☝️@IWS_Network
Read 21 tweets

Related hashtags

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just three indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3.00/month or $30.00/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!