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Chilla
@ChillaPharmD
, 4 tweets, 3 min read Read on Twitter
#Tramadol, a game of analgesic roulette, will it work or won’t it? Will your patient obtain analgesic effects or will they have a seizure, respiratory depression, or various other side effects...🤷🏼‍♀️that’s why it’s been nicknamed #Tramadont! Its variable effects are (1/3)
attributable to hepatic enzyme CYP2D6;unless you know your pt’s CYP2D6 genetic polymorphism (which I haven’t come across anyone who does)AND a comprehensive list of all of their home meds, don’t prescribe it!🙅🏼‍♀️
#pharmacyeducationboard #twitterx #medtwitter #pharmacogenomics (2/3)
Thank you to our #pharmacyresident for putting this one up, and to @DavidJuurlink & @ToxAndHound for the inspiration. 🙂💡 (3/3)
Thanks everyone!! I have been reading all the comments and feeling a little overwhelmed at the attention this board has gotten, I promise I will respond to all of you I’m just a parent working full time so it might take me a bit to get back to everyone lol
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More from @ChillaPharmD see all

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Chilla
@ChillaPharmD
“#Tramadont”, a #tweetorial

In response to the last #pharmacyeducationboard about tramadol- some are still doubting whether it has earned the moniker “Tramadont”. Points have been made that as tramadol is metabolized by CYP2D6 in the liver, so are other drugs. Should we (1/11)
just not prescribe anyone anything metabolized in the liver? Touché. The problem with CYP2D6 specifically is that it happens to have the most polymorphisms of all the CYPs enzymes. What does this mean? It means it has the greatest potential variability in activity (2/11)
from one person to another. Not only this, but unlike the other CYPs, it’s expression can vary from being absolutely nonfunctional to being an ultrarapid metabolizer because of the very unique ability of it to be duplicated! No other CYP enzyme does this!! (3/11)
Read 11 tweets

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Son 35 yrs. Undetected spondylolysthesis and other musculoskeletal issues uncovered at 13 yrs due primarily to onset of pain during a period of rapid growth.
2/ First emergency spine fusion at 15 yrs after 2 yrs of medical profession denying that kids have pain. Teens are an invisible health care population.
Columbine happened in this period.
Every teenage boy in America had a target on their forehead.
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Ẹjańlá of Talk 🎙️
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Depression
😔😔😔
is a real deal fam!

Let's do a thread. Shall we?

#Depression #EmdeeTiamiyu #YouHaveARightToBeMotivated
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© Emdee Tiamiyu

#EmdeeTiamiyu #YouHaveARightToBeMotivated
Many of us are legit raising up depressed KIDS or living with depressed "Family" members. I grew up struggling with Emotional Imbalance. In my 100 Level, I had an opportunity to OPEN UP to someone for the first time.
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fight4theyouth
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Depression is more than just feeling down.

It's a lack of motivation, increased negative emotions (anger, anxiety), a lack of concentration and memory, negative thoughts about oneself and the world (hopelessness, worthlessness), social anxiety, feeling trapped, dark imagery.
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Over 100 mil of us suffer from it.

It's existed as long as there have been human records.

Was first named as a condition 2400 years ago, by Hippocrates (in the West).

Non-human mammals can be depressed.

#mentalhealth #mentalillness
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Other negative feelings that can increase are sadness, guilt, shame, envy, and jealousy.

#mentalhealth #mentalillness #mentalhealthawareness
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IG sindivanzyl 🇿🇼🇿🇦
@sindivanzyl
When I started chronic medication for #depression , I was started on:

• Fluoxetine/ Prozac : antidepressant
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Tanmoy Goswami
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Every day next few days I'll share one #depression/#anxiety insight from my own experience. If it helps anyone a wee bit, it'll be worth it.
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