, 19 tweets, 13 min read Read on Twitter
HISTORIC Livestream Tonight: 7:30pm ET, Nov 26

#GeneEditSummit

In vitro (in the glass) genetic manipulation of artificially inseminated human eggs and sperms.

2nd: Hong Kong -- Nov, 27-29, 2018
nationalacademies.org/gene-editing/2…

1st: Wash DC -- Dec, 1-3, 2015
nationalacademies.org/gene-editing/G…
#GeneEditSummit Update 1 for citizen journalists covering 'medical': Definitely listen Dana Carroll's presentation (when archived). After listening, if it still seems too technical, then also read this book (learn their 'terms of art'!):

amazon.com/Crack-Creation…
#GeneEditSummit Update 2 for citizen journalists: transcript of Dana Carroll's presentation -- "genes genomes genetic variation" -- here: diyhpl.us/wiki/transcrip…

HT to @kanzure for the transcript.
#GeneEditSummit Update 3 for citizen journalists: follow @derek___so's live tweeting... Slightly technical, but will definitely stimulate your imagination to dig in! Full Speaker List here -- to ref his tweets against: nationalacademies.org/hk/index.html
#GeneEditSummit Update 4 for citizen journalists: Listen to Mohammed Ghaly's presentation (once archived) on the Islamic perspective of germline cell editing. Great way to transcend the 'amoral Western/ChiComm thought-box'... Summit Agenda via: nationalacademies.org/gene-editing/2…
#GeneEditSummit Update 5 for citizen journalists: referencing the "Lula and Nana" birth in China...
#GeneEditSummit Update 6 for citizen journalists: a question from audience member to "Social and Philosophical Reflections [...]" panel regarding (in vitro) "artificial wombs" for women not wishing to give birth as a (non-medical) lifestyle choice? Note to get archive/transcript.
7) #GeneEditSummit for citizen journalists: check out these two threads from biochemist Sam Sternberg (@shsternberg) regarding scientist Jiankui He and the "Lula and Nana" CRISPR babies allegedly born in China...



8) #GeneEditSummit LIVE STREAM 11/27, 10:30pm ET, 11:30am HK: panel on "Human Embryo Editing" will include Jiankui He -- the scientist behind "Lula and Nana" -- the genetically modified (CRISPR) IVF Chinese babies (twins)...

here: nationalacademies.org/gene-editing/2…
9) #GeneEditSummit Meet the Press...
10) #GeneEditSummit sidebar: Page 235 of "A Crack in Creation" (by Doudna, Sternberg) notes that, putting aside germline cell gene editing, "...the [40 year old] practice of in vitro fertilization [IVF]... never underwent formal clinical trials or FDA review." / [~4mil babies].
11) #GeneEditSummit Follow and read @derek___so and @kanzure
12) #GeneEditSummit LIVE STREAM: Jiankui He -- the scientist behind "Lulu and Nana" -- the genetically modified (CRISPR) IVF Chinese babies (twins) -- to speak soon... #CRISPRbabies #CRISPRbaby

here: livestream.com/accounts/70363…
13) #GeneEditSummit Day1, Session 2, 1h44m57s: atJennyMerchant asks atM_Balis...

"If artificial uteruses... become a reality one day will [that] solve all the gender problems and the heavy weight put on women to bear children?"

Answered at 1h48m29s.

nationalacademies.org/gene-editing/2…
14) #GeneEditSummit Day1, Session 3, 0h12m57s -- 0h31m45s: "Base" vs "CRISPR" gene editing

Not surprised to see (non-black budget) US Military (DARPA) monies behind open-source gene-editing research -- as evidenced here:

[at]DavidRLiu [at]BroadGenomics

nationalacademies.org/gene-editing/2…
16) #GeneEditSummit homework: Summit Bio of Kathy Niakan (of Crick) says she's 1st to use CRISPR on human [pre-implantation] embryos (see also Day2, Session3, Talk2). Book "Crack in Creation" (at pg214) says Junjiu Huang (of Guangzhou) was first.

nature.com/news/chinese-s…
17) #GeneEditSummit Parking this here for now. A must read investigation by @Preetika_Rana and @Lucy_Craymer. Much more on this later.

MUTANTS: Deformities Alarm Scientists Racing to Rewrite Animal DNA...

wsj.com/articles/defor…
18) #GeneEditSummit THE ANIMAL FARM: artificially inseminate sperm & egg in glass, germ-line gene-edit it using CRISPR, insert zygote into adult female. To bring forth offspring -- that make it to term, with $-margin-increasing 'traits' -- deformities notwithstanding...
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