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Tue Kragstrup
@KragstrupTW
, 7 tweets, 5 min read Read on Twitter
Selection of the main clinical studies that have impacted care of patients with RA.

Rheum core content.

#Chapter4, @eular_org online course #EULARonlinecourseOnRheumaticDiseases.

@EMEUNET initiative #EMEUNETonCourse, to promote knowledge-sharing in rheumatology.
PROMPT study.

Efficacy of methotrexate treatment in patients with probable rheumatoid arthritis: a double-blind, randomized, placebo-controlled trial.

Graphs show seropositive and seronegative patients. Something with MTX and B cells!

onlinelibrary.wiley.com/doi/epdf/10.10…
GUEPARD trial.

Evaluation of two strategies (initial methotrexate monotherapy vs its combination with adalimumab) in management of early active rheumatoid arthritis: data from the GUEPARD trial.

No long-term superiority of the MTX + ADA combination.

academic.oup.com/rheumatology/a…
BeSt trial.

Comparison of treatment strategies in early rheumatoid arthritis: a randomized trial.

Initial differences in disease activity and structural progression did not seem to persist after 10 years.

annals.org/aim/fullarticl…
RACAT trial.

Therapies for active rheumatoid arthritis after methotrexate failure.

Triple therapy added to methotrexate was noninferior to etanercept plus methotrexate in patients with MTX refractory RA.

nejm.org/doi/pdf/10.105…
ROC trial.

Non-TNF-Targeted Biologic vs a Second Anti-TNF Drug to Treat Rheumatoid Arthritis in Patients With Insufficient Response to a First Anti-TNF Drug.

Non-TNF targeted biologic showed better efficacy.

jamanetwork.com/journals/jama/…
DRESS trial.

Disease activity guided dose reduction and withdrawal of adalimumab or etanercept compared with usual care in rheumatoid arthritis.

It is indeed possible to taper TNFi therapy.

bmj.com/content/350/bm…
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Aglaia Berlutti
@Aglaia_Berlutti
Gente, para completar el hilo de ayer sobre cursos de escritura Online, hoy incluyo algunos en inglés: (todos los he revisado o al menos, escrito para saber que tal, puedo ayudarlos si se animan)
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Chris Geidner
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This was some great timing. 😊
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Matthew J. Sikora
@mjsikora
Clinical trials design for #lobular #breastcancer patients are finally available! Let's look for a moment at the Pitt Neoadjuvant Endocrine therapy trial.
lobularbreastcancer.org/clinical-trial…
#bcsm 1/
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Tinu lalala lala la la
@Tinu
Here's my lastest update Twitter #Disability & #ChronicIllness Hashtags - previous update 10.17.18

Please share it.
I'll have a PDF version of this for download on my Ko-fi by this time tomorrow. Link at the end.
HASHTAGS FOR PERSONAL NARRATIVES

These hashtags are for sharing your stories & experiences. Also good for crowdsourcing solutions.

#InvisibleIllness
#MySpoons
#MyPainDay
#ShareOurPain
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Rich Harris
@Rich_Harris
Happy to oblige! The biggest reason that a few frameworks dominate the landscape is probably straightforward inertia. Most devs (those of use who chat about this stuff on Twitter are NOT representative) don't want to investigate and learn alternatives; they have better things 1/
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Jon Hislop, MD, PhD
@HislopMD
1/n
 Dear naturopaths,

You seem to have no idea how much trouble you cause for patients, MDs, & society in general. This trouble is getting worse, & it has to STOP. Since you seem to have no insight into these issues, here are some of the (many) problems you create for us all...
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 Naturopaths, STOP making patients think they NEED lab tests from MDs! If we disagree, it can compromise our relationship with our patients by making them think they’re being denied something you just told them they HAD to have! You are SETTING US UP for a conflict with them!
3/n
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