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@AGA_Gastro highlights #NASH #NAFLD first up @VidalPuig Where do the fatty acids go? sciencedirect.com/science/articl…
#NAFLD #NASH How much does the clock matter for pathophysiology or therapeutics #circadian sciencedirect.com/science/articl…
“Lost in Translation” or Utility at Last? NASH biomarkers #genetics and risk prediction beyond PNPLA3 sciencedirect.com/science/articl…
“Metabolic inflammation is the engine that drives cellular dysfunction, cell death and deleterious remodelling within various body tissues” NAFLD #NASH #T2D #CVD sciencedirect.com/science/articl…
A worldwide prevalence of 25%. An update on the epidemiology, clinical and prognostic features and diagnostic approach to patients with #NAFLD sciencedirect.com/science/articl…
Do we understand mechanisms sufficiently to develop safe and effective targeted therapeutics beyond #weightloss #NASH #NAFLD @AGA_Gastro sciencedirect.com/science/articl…
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#NASH #NAFLD #circadian #genetics #T2D #CVD #weightloss

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Amy Proal
@microbeminded2
Incredibly important hypothesis piece published today 👉 “Proposed here is a theory that #microorganisms from within the #brain and elsewhere in the body contribute to the long-term #neurological deterioration characteristic of traumatic brain injury”: sciencedirect.com/science/articl…
From paper 👉 1. “First, since the normal human #brain is not sterile, but is host to a variety of microorganisms, blows to the #skull may dislodge them from their accustomed local environments, in which they have been living in quiet equilibrium with neighboring #brain cells”
2. “2nd, upon impact commensal #microbes already resident on surfaces of the nose, mouth + eyes, and potentially harmful organisms from the environment, may gain access to the #brain through the distal ends of the olfactory + optic #nerves or even a disrupted blood-brain barrier”
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Dr. Cecilia Tomori
@DrTomori
@sophiejrigney @elizabethmoya @makesmilk @babyfriendly Anthropologist here - I have written about changing ideas about #time and about the regulation of infants quite a bit. These are #culturalideologies that came about in late 19th-early 20th century in response to social changes 1/n
@sophiejrigney @elizabethmoya @makesmilk @babyfriendly the rise of industrial #capitalism changed labor practices and emphasized efficiency and predictability. The #clock was particularly important in this regard.
@sophiejrigney @elizabethmoya @makesmilk @babyfriendly There was a fundamental reworking of #time from a very different understanding - agricultural labor has a very different rhythm (EP Thompson famously wrote about this) jstor.org/stable/649749?…
Read 9 tweets
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Manoj Doss
@ManojDoss
First real microdosing study reveals that low doses of #LSD increase estimation of time intervals:
link.springer.com/article/10.100…
The authors refer to to this as "temporal dilation." However, similar to drug studies in episodic memory, there's an encoding vs. retrieval problem here. 1/n
If participants encode the initial interval in a temporally dilated state (time is perceived to be longer), then their reproductions will be longer. However, if the passage of time feels longer during reproduction, then shorter intervals should be reproduced. 2/n
For example, let's pretend you thought to yourself that an initial interval felt like 3 seconds (and it actually was). When you're reproducing it under a state in which time feels twice as long, you would think that 3 seconds passed when actually only 1.5 seconds had passed. 3/n
Read 14 tweets
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yestiseye
@yestiseye
@OskaArcher @MarkDuffett So a slight delay… my team of simians jetted in from Japan overnight where it looks like they had a quite lovely time… they had to drop off a NEG at Labor Party HQ en route however 😼
@OskaArcher @MarkDuffett I figured in the end that the "contour" format was best with a large dataset. Full year's correlation data for SA with other states (Qld though only recently introduced wind generation into the mix, so I used the "shade" format instead)
@OskaArcher @MarkDuffett Next I'll get Queensland out of the way since other than showing what one, then what looks like a second wind farm coming on stream looks like, the correlations have limited value. #whtr
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Valerie tweets progress.
@SfPRocur
Good morning!

Today I want to talk about #TheDarkSideOfScience.

More specifically about the fact that *science is hard*
1. Because it really helps to know that you're not alone, you're not a failure, you are in fact - a genius. All of you!
2. Non-scientists don't always know that a lot of research is redoing an experiment that hasn't quite worked yet. Or obtaining negative results*

*By the way, negative results are still results!
Read 12 tweets
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Bob Berwyn
@bberwyn
mountains, snow, avalanches and climate at #ISSW2018
Now sitting in on a session with @oeav on excessive ski area development in Tirol.
Lots of ski areas in Tirol, more lifts planned as resorts try to outrace #globalwarming. But it’s too much, says @oeav - seele-der-alpen.at
Read 51 tweets

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