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Exponential increase in cases in US and in the 🌍 since our last IBD live.
Recent @CDCgov prelim US data as of 03/16: 45% of hospitalizations, 53% of ICU admissions and 80% deaths among patients >65yo 2/
As prev. discussed, studies show SARS-CoV-2 can be found in the stool of patients with #COVID19. This more recent study shows stool tests stay + for a mean or 11 days after resp samples have become neg. 1 stayed + up to 47 days after symptom onset! 3/
What are implications for endoscopy? Likely multiple transmission routes in the endo unit. Important to use the right #PPE for your cases. 4/
Digestive symptoms are common. Up to 50% of patients with #COVID19 have GI symptoms on admission. In another study, 16% of patients with #COVID19 only presented with GI symptoms. 5/
Anosmia and dysgeusia have been reported with COVID19, no published data so far, but these symptoms have been described with other coronaviruses. Keep this in mind! 6/
Liver enzymes are often elevated in patients with #COVID19, and even more so in patients with severe disease 7/
Does the blood group matter? This is a preprint, NOT peer-reviewed yet. 8/
Are men more affected by #COVID19? 9/
Treatment updates: lopinavir-ritonavir not helpful in an RCT @NEJM. (Hydroxy)chloroquine promising but unclear if clinical benefit. Other agents under investigation, including possibly adalimumab? in an RCT in China 10/
#COVID19 and IBD: interesting preprint on preventive measures taken by an IBD Center in Wuhan. 11/
We now have more data on IBD and #COVID19 via the SECURE-IBD registry. 87 patients reported as of 3/25. Data posted on covidibd.org. Thank you @ryanungaro and team for the updates this AM! 12/
#IBD and #COVID19: There are some great resources for health care providers and patients by @CrohnsColitisFn @AmCollegeGastro. Awaiting #IOIBD recommendations to help guide management. 13//
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