1/ Do I need the vaccine if I’ve already been infected w/ COVID-19? Isn’t natural immunity better?

A: COVID-19 vaccines produce STRONGER & MORE CONSISTENT antibody responses than natural infection, meaning EVERYONE can benefit from the protection.

💥Don’t give away your shot!
2/ As more people become eligible for the COVID-19, we’ve heard some people who’ve already been infected, especially younger people, doubting whether they need the vaccine.
3/ We now have good evidence that vaccines produce HIGHER antibody levels on average against SARS-CoV-2 than natural infection, & people vaccinated after previous infection get a BIG boost.
4/ In fact, a single dose of vaccine after a COVID-19 infection provides a boost of immunity in many cases HIGHER than the immune response for never infected individuals after two doses of the #vaccine.

@florian_krammer

medrxiv.org/content/10.110…?
5/ There are still many unknowns about natural #immunity to SARS-CoV-2. Natural immunity is highly variable-for many it is high & durable, but some people produce low levels of #antibodies or ones that fall quickly.

thelancet.com/journals/lanmi…
6/ Vaccines also likely protect better against the new variants. A study found that blood from previous COVID-19 patients was less effective at neutralizing the B.1.351 variant.
7/ After 1 dose of vaccination w/ Pfizer or Moderna shot, those antibodies rose a 1000-fold and could neutralize the new variant…. as well as the original SARS-CoV-1 virus from 2003 (WOW!).

medrxiv.org/content/10.110…?
8/ A recent studyt tested how well blood from previously infected COVID-19 patients compared to vaccinated individuals could neutralize 4 different SARS-CoV-2 variants including the more transmissible B.1.1.7.

jamanetwork.com/journals/jama/…?
9/ This figure shows that antibodies from vaccinated individuals on average had much higher neutralizing activity against all variants than did blood from people previously infected with COVID-19.
10/ Finally, a recent study in pregnant women also found that vaccine-induced immune responses were significantly higher than the response in pregnant women with natural infection.

pubmed.ncbi.nlm.nih.gov/33758889/
11/ Even better, vaccinated women passed on much higher levels of protective antibodies to their fetus or newborn than the women with antibodies from previous COVID-19 infection.

#pregnancy @BumpClubBeyond
12/ ⬇️ BOTTOM LINE:

💥COVID-19 vaccination provides stronger & less variable antibody response than natural SARS-CoV-2 infection.

💥 Getting a vaccine after a COVID-19 infection provides a turbo-boost of immunity, which may be particularly helpful against new variants.
13/ 💥 Even if you’ve had a confirmed previous infection, getting vaccinated can dramatically increase your protection.

Don’t give away your shot!

Love,
Those Nerdy Girls

#vaccines #antibodies #immunology #variants #NerdyGirlNation
14/ Additional links: nejm.org/doi/10.1056/NE…?

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Dear Pandemic

Dear Pandemic Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @DearPandemic

29 Mar
1/ A: Make a copy, share it with your primary care provider, think before sharing it on social media, probably best not to laminate the original, and don’t panic if you lose it. 📱👛🍩
2/ 👌 DO THIS with your COVID-19 Vaccination Record Card:

📷 Take a photo of the card.

Snap a photo of your official #CDC or other government-issued #vaccinationcard in case it gets lost. Take a photo after the first shot, and another one after your second shot.
3/ 👩‍⚕️Send it to your primary care provider.

Upload a copy of the completed vaccination card to main clinician or to your online medical chart so it can be included in your official vaccination records.
Read 14 tweets
27 Mar
1/ Q: What is going on with the results from the United States AstraZeneca trial?

A: Despite a *strange* communication week, the new trial results show that the #Oxford/#Astrazeneca is safe & effective. GOOD NEWS!
2/ TLDR: The first results this week were based on data collected in the U.S. through a pre-specified end date for interim analysis of Feb 17th. They continued to collect data beyond that date & have now released updated results..spoiler alert..they are very similar (76% vs 79%). Efficacy Table from Dr. Eri...
3/ On March 22nd, @AstraZeneca reported results (by press release) but received push-back on March 23rd from the U.S. Data Safety & Monitoring Board who claimed the press release efficacy was not based on full data. astrazeneca.com/media-centre/p…
Read 10 tweets
10 Mar
Time to meet another Nerdy Girl! Introducing Dr. @shoshiaronowitz! Dr. Aronowitz is a researcher & clinician studying low-barrier substance use treatment, innovative delivery of harm reduction supplies, racial disparities in pain treatment in the context of the overdose crisis...
2/...the intersection of criminal justice and healthcare, and reproductive/sexual health.

Here at Dear Pandemic, Dr. Aronowitz is the lead on our (rather amazing) Instagram account. We have her to thank for the pithy, graphical & lovable Insta feed.

instagram.com/dear_pandemic/
3/ Prior to the pandemic, Dr. Aronowitz described herself as a nurse researcher focused on health equity, a clinician providing reproductive healthcare and substance use care, and a harm reduction community organizer. sciencedirect.com/science/articl…
Read 27 tweets
9 Mar
1/ It’s Good News Tues!

Yesterday, the United States @CDCgov issued new guidelines stating that 👏🏼 fully 👏🏼vaccinated 👏🏼 people can safely:

1️⃣ Visit other #vaccinated people indoors--without wearing masks or physically distancing! 😷
2/ 2️⃣ Visit unvaccinated people--without wearing masks or physical distancing, as long as the unvaccinated people (& the people they live with) are low risk for severe #COVID!

bit.ly/3qymfgT
3/ 3️⃣ Skip #quarantine & testing if they are exposed to someone who has #COVID19! But, do monitor for symptoms for 14 days, get tested, & start quarantining if symptoms develop. Remember, symptoms can be all over the map, & might be quite mild (especially after vaccination).
Read 20 tweets
8 Mar
1/ A: Celebrate the mild #flu season & take what we have learned this year to inform future behavior. Harmful germs are not going away. 🦠 Illness from bacteria & viruses that make us sick do not “strengthen” the #immune system & contribute to significant complications & death. Image
2/ The lack of infectious illnesses will not #weaken your #immunesystem. Public health measures to combat #COVID19 including social distancing, masks, & extra hand washing greatly reduced the incidence of some bad microbes that cause common infectious illnesses such as the flu.
3/ More than 15,000 US deaths attributed to the #flu were averted this year. Other common viruses, like rhinoviruses, did not decrease as consistently. #Bacteria & #viruses that cause illness will continue to exist. go.nature.com/2OxkiUv
Read 9 tweets
4 Mar
1/ Q: Can I go back to my indoor #fitness classes? 🚴‍♀️

A: The #NerdyGirls LOVE your efforts to stay fit 💪, but best to hang on to those online or outdoor workouts a bit longer.

TL;DR: Heavy breathing, no masks, and indoors is the perfect recipe for #SARSCoV2 #transmission.
2/ A recent U.S. @CDCgov report described an #outbreak linked to an unnamed fitness facility in #Chicago in which *55 out of 81* attendees of an indoor high-intensity fitness class in Chicago were infected over the course of a week in August 2020.
3/ ❓What precautions were being taken?

➡️ The classes were at <25% capacity, with masks 😷, temperature & symptom checks required at entry. 🤒 Exercise mats were spaced 6 feet/2 meters apart. ↔️
Read 13 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!

Follow Us on Twitter!